ALEXIS Biochemicals: Polyclonal Antibody to Glucocorticoid Receptor

ALX-210-155

Revised 11-Nov-05

Polyclonal Antibody to Glucocorticoid Receptor
SYNONYMS	anti-GR PAb
PRODUCT LINE	DNA Regulation / Transcription
PRODUCT CATEGORY	Glucocorticoids & Glucocorticoid Receptors / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-155-R200		200 µl	355.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Rat
SOURCE/HOST:	From rabbit.
FORMULATION:	Liquid. Antiserum diluted in PBS containing 0.05% sodium azide.
IMMUNOGEN:	Synthetic peptide corresponding to aa 150-175 (A¹⁵⁰PIEKEIPKIHSDVSSEQQHLKGQTG¹⁷⁵) of human GR (glucocorticoid receptor).
SPECIFICITY:	Recognizes human and rat GR. Detects a band of ~97kDa by Western blot.
APPLICATION:	Gel Supershift Assay Immunocytochemistry (1:100) Immunoprecipitation Western Blot (1:100)
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
HANDLING:	Avoid freeze/thaw cycles.

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General Information

Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Glucocorticoids are a family of steroids necessary for the regulation of energy metabolism and the immune and inflammatory responses. These compounds exert their effect through their interaction with the glucocorticoid receptor (GR) and that complex's subsequent association with DNA. All normal mammalian tissues examined to date have been shown to contain glucocorticoid receptor.

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Polyclonal Antibodies

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