ALEXIS Biochemicals: Polyclonal Antibody to NALP1 (human) (AL176)

ALX-210-904

Revised 25-Jan-08

Polyclonal Antibody to NALP1 (human) (AL176)
SYNONYMS	anti-NACHT-, LRR- and PYD-containing Protein 1 (human) PAb (AL176) anti-DEFCAP (human) PAb (AL176) anti-NAC (human) PAb (AL176) anti-CARD7 (human) PAb (AL176) anti-Caspase Recruitment Domain-containing Protein 7 (human) PAb (AL176)
PRODUCT LINE	Inflammation
PRODUCT CATEGORY	Inflammasome

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-904-R100		100 µl	270.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human
SOURCE/HOST:	From rabbit.
PURITY:	Affinity purified.
FORMULATION:	Liquid. Neat serum.
IMMUNOGEN:	Synthetic peptide corresponding to aa 2-25 (A²GGAWGRLACYLEFLKKEELKEFQ²⁵) of N-terminal human NALP1 (NACHT-, LRR- and PYD-containing protein 1).
SPECIFICITY:	Recognizes human NALP1. Does not cross-react with mouse NALP1.
APPLICATION:	Western Blot
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 1 year after receipt when stored as recommended.
HANDLING:	Avoid freeze/thaw cycles.
POSITIVE CONTROL:	For Positive Control (Western blot) see Prod. No. ALX-840-603.

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Product Specific Literature References

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta: F. Martinon; Mol. Cell. 10, 417 (2002) Abstract

General Information

MANUFACTURER

Manufactured by Apotech Corporation.

General Literature References

Signalling: Initiation of pro-IL-1beta processing: E. Bell; Nat. Rev. Immunol. 2, 719 (2002), (Review) Abstract
The PYRIN-CARD protein ASC is an activating adaptor for caspase-1: S.M. Srinivasula, et al.; J. Biol. Chem. 277, 21119 (2002) Abstract
NALPS: a novel protein family involved in inflammation: J. Tschopp, et al.; Nat. Rev. Mol. Cell Biol. 4, 95 (2003), (Review) Abstract; Full Text

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Polyclonal Antibodies • Caspase Recruitment Domain [CARD] Proteins/Related Products

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