ALEXIS Biochemicals: Polyketomycin

ALX-380-127

Revised 30-Jun-08

Polyketomycin
SYNONYMS	Antibiotic K99-5147
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antibiotics Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-127-M001		1 mg	100.00 USD

Product Specification

FORMULA:	C₄₄H₄₈O₁₈
MW:	864.9
CAS NUMBER:	200625-47-4
SOURCE/HOST:	Isolated from Streptomyces sp.
PURITY:	≥98% (HPLC)
APPEARANCE:	Orange to dark brown solid.
SOLUBILITY:	Soluble in DMSO, methanol or acetone.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
IDENTITY:	Identity determined by ¹H-NMR.

Product Description

Tetracyclic quinone glycoside. Displays antibacterial, antimalarial and antitumor activity.

Product Specific Literature References

Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1. I. Taxonomy, production, isolation, physico-chemical properties and biological activities: I. Momose, et al.; J. Antibiot. 51, 21 (1998) Abstract
Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1. II. Structure determination: I. Momose, et al.; J. Antibiot. 51, 26 (1998) Abstract
Biosynthesis of polyketomycin produced by Streptomyces diastatochromogenes Tü 6028: T. Paululat, et al.; J. Antibiot. 52, 96 (1999) Abstract
In vitro antimalarial activities of the microbial metabolites: K. Otoguro, et al.; J. Antibiot. 56, 322 (2003) Abstract
Synthesis of the polyketomycin disaccharide: D.S. Micalizzi, et al.; Tetrahedron: Asymmetry 14, 3183 (2003)

Further Categories Containing This Product:

Antibiotics - Antimalarial • Antitumor Antibiotics

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