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ALX-620-054 Revised 11-Oct-06
4AF DA
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SYNONYMS 4-Aminofluorescein diacetate
PRODUCT LINE Nitric Oxide Pathway
PRODUCT CATEGORY Nitric Oxide & NOS Detection/Related Products
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ALX-620-054-M001   1 mg 136.00 USD Add To Cart
Product Specification
FORMULA: C24H17NO7
MW: 431.4
PURITY: ≥99% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in DMSO.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HANDLING: Protect from light. Keep under inert gas.

Product Description
Negative control compound for the fluorescent probes DAF-2 (Prod. No. ALX-620-052) and DAF-2 DA (Prod. No. ALX-620-056).
Product Specific Literature References
Direct evidence of NO production in rat hippocampus and cortex using a new fluorescent indicator: DAF-2 DA: H. Kojima, et al.; Neuroreport 9, 3345 (1998) Abstract
Further Categories Containing This Product:
Dyes/Stains/Fluorescent Probes/Fluorescent Labels
 
 
ALX-620-029 Revised 05-May-08
ABD-F
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SYNONYMS 4-Fluoro-7-sulfoamoylbenzofurazan
PRODUCT LINE Other Products
PRODUCT CATEGORY Dyes/Stains/Fluorescent Probes/Fluorescent Labels
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ALX-620-029-M010   10 mg 95.00 USD Add To Cart
ALX-620-029-M050   50 mg 320.00 USD Add To Cart
Product Specification
FORMULA: C6H4FN3O3S
MW: 217.2
CAS NUMBER: 91366-65-3
PURITY: ≥99%
APPEARANCE: White to yellow powder.
SOLUBILITY: Soluble in acetonitrile.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light and moisture.

Product Description
Highly reactive fluorogenic reagent for labelling thiol compounds. Selectively labels protein cysteine residues without side chain modification or N-terminal blockage. Potent vasorelaxant.
Product Specific Literature References
New Fluorogenic Reagent Having Halogenobenzofurazan Structure for Thiols: 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole: T. Toyo'oka and K. Imai; Anal. Chem. 56, 2461 (1984)
Isolation and characterization of cysteine-containing regions of proteins using 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole and high- performance liquid chromatography: T. Toyo'oka and K. Imai; Anal. Chem. 57, 1931 (1985)
Amino acid composition analysis of minute amounts of cysteine- containing proteins using 4-(aminosulfonyl)-7-fluoro-2,1,3- benzoxadiazole and 4-fluoro-7-nitro-2,1,3-benzoxadiazole in combination with HPLC: T. Toyo'oka, et al.; Biomed. Chromatogr. 1, 15 (1986) Abstract
Fluorometric assay of thiols with fluorobenzoxadiazoles: K. Imai and T. Toyo'oka; Meth. Enzymol. 143, 67 (1987) Abstract
 
 
ALX-350-255 Revised 03-Apr-08
(+)-cis,trans-Abscisic acid
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SYNONYMS (S)-5-(1-Hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methyl-[2Z,4E]-pentadienoic acid
(+)-cis,trans ABA
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Natural Products - Plant Research Reagents
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ALX-350-255-C500   500 µg 90.00 USD Add To Cart
ALX-350-255-M001   1 mg 160.00 USD Add To Cart
ALX-350-255-M005   5 mg 620.00 USD Add To Cart
Product Specification
FORMULA: C15H20O4
MW: 264.3
CAS NUMBER: 21293-29-8
MERCK INDEX: 14: 11
SOURCE/HOST: Isolated from Curvularia lunata.
PURITY: ≥97%
APPEARANCE: Off-white powder.
SOLUBILITY: Soluble in ethanol or DMSO.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Protect from light.

Product Description
Natural and active isomer of the abscission accelerating plant hormone.
Product Specific Literature References
Metabolism and physiology of abscisic acid: J.A.D. Zeevaart & R.A. Creelman; Annu. Rev. Plant Physiol. Plant Mol. Biol. 39, 439 (1988), (Review)
Molecular responses to drought and cold stress: K. Shinozaki & K. Yamaguchi-Shinozaki; Curr. Opin. Biotechnol. 7, 161 (1996), (Review) Abstract
Abscisic acid and signal transduction: J. Leung & J. Giraudat; Annu. Rev. Plant Physiol. Plant Mol. Biol. 49, 199 (1998), (Review)
ABA signal transduction: E. Grill & A. Himmelbach; Curr. Opin. Plant Biol. 1, 412 (1998), (Review) Abstract
Signal transduction networks and the biology of plant cells: M.J. Chrispeels, et al.; Biol. Res. 32, 35 (1999), (Review) Abstract
Abscisic acid: A.M. Hetherington; Curr. Biol. 9, R390 (1999), (Review) Abstract
Regulation of abscisic acid-induced stomatal closure and anion channels by guard cell AAPK kinase: J. Li, et al.; Science 287, 300 (2000) Abstract
Mitogen-activated protein kinase and abscisic acid signal transduction: S. Heimovaara-Dijkstra, et al.; Results Probl. Cell Differ. 27, 131 (2000) Abstract
Relay and control of abscisic acid signaling: A. Himmelbach, et al.; Corr. Opin. Plant Biol. 6, 470 (2003), Review Abstract
Nitric oxide induced by hydrogen peroxide mediates abscisic acid-induced activation of the mitogen-activated protein kinase cascade involved in antioxidant defense in maize leaves: A. Zhang, et al.; New Phytol. 175, 36 (2007) Abstract
Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger: S. Bruzzone, et al.; PNAS 104, 5759 (2007) Abstract
Further Categories Containing This Product:
Natural Products - Nitric Oxide Pathway Modulators • Plant Research Reagents/Related Products
 
 
ALX-630-093 Revised 23-Jul-08
Aflatoxin B1
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
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ALX-630-093-M001   1 mg 28.00 USD Add To Cart
ALX-630-093-M005   5 mg 110.00 USD Add To Cart
Product Specification
FORMULA: C17H12O6
MW: 312.3
CAS NUMBER: 1162-65-8
MERCK INDEX: 14: 180
RTECS: GY1925000
SOURCE/HOST: Isolated from Aspergillus flavus.
PURITY: ≥98% (HPLC)
APPEARANCE: White to yellow powder.
SOLUBILITY: Soluble in DMSO (20mg/ml) or methylene chloride (10mg/ml).
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HAZARD: VERY TOXIC. MAY BE CARCINOGENIC. MAY BE TERATOGENIC.

Product Description
Naturally occuring mycotoxin produced by many species of Aspergillus. Metabolized by the liver to the reactive intermediate aflatoxin M1. Exposure may produce acute necrosis, cirrhosis and carcinoma of the liver. Induces DNA damage.
Product Specific Literature References
Molecular dosimetry of aflatoxin exposure: contribution to understanding the multifactorial etiopathogenesis of primary hepatocellular carcinoma with particular reference to hepatitis B virus: C.P. Wild, et al.; Environ. Health Perspect. 99, 115 (1993) Abstract
A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People's Republic of China: G.S. Qian, et al.; Cancer Epidemiol. Biomarkers Prev. 3, 3 (1994) Abstract
Aflatoxin B1 induced lacI mutation in liver and kidney of transgenic mice C57BL/6N: effect of phorone: H. Autrup, et al.; Mutagenesis 11, 69 (1996) Abstract
Activation and detoxication of aflatoxin B1: F.P. Guengerich, et al.; Mutat. Res. 402, 121 (1998), (Review) Abstract
Hyperplasia, partial hepatectomy, and the carcinogenicity of aflatoxin B1: B.D. Roebu; J. Cell. Biochem. 91, 242 (2004), (Review) Abstract
Aflatoxin B1-induced DNA damage and its repair: L. L. Bedard & T. E. Massey; Cancer Lett. 241, 174 (2006), (Review) Abstract
General Information
Not for sale in U. S. A.
Further Categories Containing This Product:
Carcinogens & Tumor Promoters Other Products • Plant Research Reagents/Related Products • Natural Products - Plant Research Reagents • Natural Products - Other Tumor Promoters • Non-apoptotic Cell Death/Necrosis
 
 
ALX-630-103 Revised 10-Sep-07
Aflatoxin B2
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
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ALX-630-103-M001   1 mg 55.00 USD Add To Cart
ALX-630-103-M005   5 mg 260.00 USD Add To Cart
Product Specification
FORMULA: C17H14O6
MW: 314.3
CAS NUMBER: 7220-81-7
MERCK INDEX: 14: 180
RTECS: GY1722000
SOURCE/HOST: Isolated from Aspergillus flavus.
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in methylene chloride, DMSO or methanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HAZARD: VERY TOXIC. MAY BE CARCINOGENIC.

Product Description
Potent hepatotoxic and hepatocarcinogenic mycotoxin.
Product Specific Literature References
Aflatoxin B2: Chemical Identity and Biological Activity: S.B. Chang, et al.; Science 142, 1191 (1963) Abstract
Accumulation of only aflatoxin B2 by a strain of Aspergillus flavus: H.W. Schroeder & W.W. Carlton; Appl. Microbiol. 25, 146 (1973) Abstract
In vitro metabolism of aflatoxin B2 by animal and human liver: B.D. Roebuck, et al.; Cancer Res. 38, 999 (1978) Abstract
Interaction of aflatoxin B2 with rat liver DNA and histones in vivo: J.D. Groopman, et al.; Carcinogenesis 2, 1371 (1981) Abstract
General Information
Not for sale in U. S. A.
Further Categories Containing This Product:
Plant Research Reagents/Related Products • Carcinogens & Tumor Promoters Other Products • Natural Products - Plant Research Reagents • Natural Products - Other Tumor Promoters • Non-apoptotic Cell Death/Necrosis
 
 
ALX-630-104 Revised 20-Mar-08
Aflatoxin G1
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
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ALX-630-104-M001   1 mg 65.00 USD Add To Cart
ALX-630-104-M005   5 mg 260.00 USD Add To Cart
Product Specification
FORMULA: C17H12O7
MW: 328.3
CAS NUMBER: 1165-39-5
MERCK INDEX: 14: 181
RTECS: LV1720000
SOURCE/HOST: Isolated from Aspergillus flavus.
PURITY: ≥98% (HPLC)
APPEARANCE: White to yellow powder.
SOLUBILITY: Soluble in DMSO (10mg/ml), methylene chloride (5mg/ml) or methanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HAZARD: MAY BE CARCINOGENIC. VERY TOXIC.

Product Description
Potent hepatotoxic and hepatocarcinogenic mycotoxin.
Product Specific Literature References
Mutagenic effect of aflatoxin G1 in comparison with B1: M.M. el-Zawahri, et al.; J. Environ. Pathol. Toxicol. Oncol. 10, 45 (1990) Abstract
Identification of an aflatoxin G1-serum albumin adduct and its relevance to the measurement of human exposure to aflatoxins: G. Sabbioni & C.P. Wild; Carcinogenesis 12, 97 (1991) Abstract
Effects of sterigmatocystin, deoxynivalenol and aflatoxin G1 on apoptosis of human peripheral blood lymphocytes in vitro: X.M. Sun, et al.; Biomed. Environ. Sci. 15, 145 (2002) Abstract
General Information
Not for sale in U. S. A.
Further Categories Containing This Product:
Plant Research Reagents/Related Products • Carcinogens & Tumor Promoters Other Products • Natural Products - Plant Research Reagents • Natural Products - Other Tumor Promoters • Non-apoptotic Cell Death/Necrosis
 
 
ALX-630-106 Revised 20-Jun-08
Aflatoxin G2
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
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ALX-630-106-M001   1 mg 150.00 USD Add To Cart
ALX-630-106-M005   5 mg 600.00 USD Add To Cart
Product Specification
FORMULA: C17H14O7
MW: 330.3
CAS NUMBER: 7241-98-7
MERCK INDEX: 14: 181
RTECS: LV1700000
SOURCE/HOST: Isolated from Aspergillus flavus.
PURITY: ≥98% (HPLC)
APPEARANCE: Off-white to yellow powder.
SOLUBILITY: Soluble in methylene chloride (5mg/ml), DMSO or methanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HAZARD: VERY TOXIC. MAY BE CARCINOGENIC.

Product Description
Potent hepatotoxic and hepatocarcinogenic mycotoxin.
Product Specific Literature References
Combining Ability for Resistance to Field Aflatoxin Accumulation in Maize Grain: D.P. Gorman, et al.; Plant Breeding 109, 296 (1992)
Mutagenicity of aflatoxins related to their metabolism and carcinogenic potential: J.J. Wong & D.P. Hsieh; PNAS 73, 2241 (1976) Abstract
General Information
Not for sale in U. S. A.
Further Categories Containing This Product:
Plant Research Reagents/Related Products • Carcinogens & Tumor Promoters Other Products • Natural Products - Plant Research Reagents • Natural Products - Other Tumor Promoters • Non-apoptotic Cell Death/Necrosis
 
 
ALX-630-114 Revised 13-Jun-08
Aflatoxin M2
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SYNONYMS 4-Hydroxyaflatoxin B2
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
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ALX-630-114-MC01   0.1 mg 250.00 USD Add To Cart
Product Specification
FORMULA: C17H14O7
MW: 330.3
CAS NUMBER: 6885-57-0
MERCK INDEX: 14: 182
RTECS: GY1720000
SOURCE/HOST: Isolated from Aspergillus flavus.
PURITY: ≥98% (HPLC, TLC)
APPEARANCE: White to light yellow powder.
SOLUBILITY: Soluble in DMSO or methanol; insoluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light.
HAZARD: VERY TOXIC. MAY BE CARCINOGENIC.

Product Description
Potent hepatotoxic and hepatocarcinogenic mycotoxin. Metabolite of aflatoxin B2. DNA-damaging agent.
Product Specific Literature References
Milk of mammals fed an aflatoxin-containing diet.: H. De Iongh, et al.; Nature 202, 466 (1964) Abstract
Isolation and structure of aflatoxins M1 and M2: C.W. Holzapfel, et al.; Tetrahedron Lett. 25, 2799 (1966) Abstract
Acute toxicity of aflatoxins M1 and M2 in one-day-old ducklings: I.F. Purchase; Food Cosmet. Toxicol. 5, 339 (1967) Abstract
Occurrence of aflatoxins M(1) and M(2) in milk commercialized in Ribeirão Preto-SP, Brazil: N.S. Garrido, et al.; Food Addit. Contam. 20, 70 (2003) Abstract
Further Categories Containing This Product:
Plant Research Reagents/Related Products • Carcinogens & Tumor Promoters Other Products • Natural Products - Plant Research Reagents • Natural Products - Other Tumor Promoters
 
 
ALX-630-095 Revised 03-Apr-08
Aflatoxin M1
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
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ALX-630-095-MC01   0.1 mg 80.00 USD Add To Cart
Product Specification
FORMULA: C17H12O7
MW: 328.3
CAS NUMBER: 6795-23-9
MERCK INDEX: 14: 182
RTECS: GY1880000
SOURCE/HOST: Isolated from Aspergillus flavus.
PURITY: ≥95% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in methylene chloride (1mg/ml).
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HAZARD: MAY BE MUTAGENIC. MAY BE CARCINOGENIC. VERY TOXIC.

Product Description
Potent hepatotoxic and hepatocarcinogenic mycotoxin. Hydroxylated metabolite of aflatoxin B1.
Product Specific Literature References
Production and characterization of monoclonal antibodies against aflatoxin M1: N.A. Woychik, et al.; Appl. Environ. Microbiol. 48, 1096 (1984) Abstract; Full Text
Comparative binding and sequence interaction specificities of aflatoxin B1, aflatoxicol, aflatoxin M1, and aflatoxicol M1 with purified DNA: K. Marien, et al.; J. Biol. Chem. 262, 7455 (1987) Abstract; Full Text
Presence of aflatoxin M1 in commercial ultra-high-temperature-treated milk.: J.L. Blanco, et al.; Appl. Environ. Microbiol. 54, 1622 (1988) Abstract; Full Text
Distribution and stability of aflatoxin M1 during processing, ripening and storage of Telemes cheese: A. Govaris, et al.; Food Addit. Contam. 18, 437 (2001) Abstract
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