ALEXIS Biochemicals: Proendothelin-1 (human) (recombinant)

ALX-201-032

Revised 08-Feb-06

Proendothelin-1 (human) (recombinant)
SYNONYMS	ProET-1 (human) (recombinant)
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Endothelins [ETs] & Endothelin Receptors/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-201-032-C004		4 µg	190.00 USD

Product Specification

MW:	~26kDa.
SOURCE/HOST:	Produced in XL1-Blue cells. Human proendothelin-1 (aa 18-212) is fused to a His-tag. The N-terminal peptide sequence Met-Arg-Gly-Ser-(His)₆ replaces the signal peptide.
PURITY:	~80% (SDS-PAGE)
FORMULATION:	Lyophilized. Contains no preservatives.
RECONSTITUTION:	Reconstitute in sterile water.
BIOLOGICAL ACTIVITY:	4µg (160pmoles) of recombinant human proendothelin-1 when cleaved with furin and chymosin has been shown to produce endothelin-1 mediated vasoconstriction of rat vas deferens and rabbit carotid artery.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	+4°C

Product Specific Literature References

Processing of proendothelin-1 by human furin convertase: J.-B. Denault, et al.; FEBS Lett. 362, 276 (1995) Abstract

General Information

BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link P25101: Endothelin-1 (human) (precursor)
AfCS Signalling Gateway link A000062: Endothelin-1 (mouse)

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