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ALX-340-028 Revised 25-Aug-08
Prostaglandin E2
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SYNONYMS Dinoprostone
PRODUCT LINE Inflammation
PRODUCT CATEGORY Prostaglandins & Prostaglandin Analogs
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-340-028-M001   1 mg 28.00 USD Add To Cart
ALX-340-028-M005   5 mg 123.00 USD Add To Cart
ALX-340-028-M010   10 mg 218.00 USD Add To Cart
Product Specification
FORMULA: C20H32O5
MW: 352.5
CAS NUMBER: 363-24-6
MERCK INDEX: 14: 7877
PURITY: ≥99%
APPEARANCE: White to off-white crystalline solid.
SOLUBILITY: 100mg/ml soluble in 100% ethanol, DMSO or dimethyl formamide; sparingly soluble in PBS, pH 7.2 (5mg/ml).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 2 years after receipt when stored at -20°C. Avoid basic solutions (pH > 7.4), since Prostaglandin E2 will degrade to PGA and PGB. We do not recommend storing aqueous solutions for more than one day.

Product Description
One of the primary cyclooxygenase (COX) products of arachidonic acid and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. Affinity constants (Kd) of PGE2 for these receptors range from 1-10nM depending on the receptor subtype and tissue.
 
 

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