ALEXIS Biochemicals: Prostaglandin J2, 15-Deoxy-Δ12,14-

ALX-340-022

Revised 29-Aug-08

Prostaglandin J2, 15-Deoxy-Δ12,14-
PRODUCT LINE	Inflammation
PRODUCT CATEGORY	Prostaglandins & Prostaglandin Analogs

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-340-022-C500		500 µg	85.00 USD
ALX-340-022-M001		1 mg	150.00 USD

Product Specification

FORMULA:	C₂₀H₂₈O₃
MW:	316.4
CAS NUMBER:	87893-55-8, 89886-60-2
CONCENTRATION:	1mg/ml
PURITY:	≥97%
FORMULATION:	Liquid. Solution in mehtyl acetate.
SOLUBILITY:	20mg/ml soluble in 100% ethanol, DMSO or dimethyl formamide; 2.7mg/ml soluble in PBS, pH 7.2
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 1 year after receipt when stored at -20°C. May polymerize in basic solutions. Keep aqueous solutions on ice and use within 12 hours.
HAZARD:	IRRITANT. FLAMMABLE.

Product Description

Suggested natural ligand for the γ-isoform of the nuclear peroxisome proliferator activated receptor (PPARγ).

Product Specific Literature References

Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro: F.A. Fitzpatrick and M.A. Wynalda; J. Biol. Chem. 258, 11713 (1983) Abstract; Full Text
9-Deoxy-delta 9, delta 12-13,14-dihydroprostaglandin D2, a metabolite of prostaglandin D2 formed in human plasma: Y. Kikawa, et al.; PNAS 81, 1317 (1984) Abstract
15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma: B.M. Forman, et al.; Cell 83, 803 (1995) Abstract
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation: S.A. Kliewer, et al.; Cell 83, 813 (1995) Abstract

General Information

BACKGROUND/TECHNICAL INFORMATION

To change the solvent, evaporate the methyl acetate under a gentle stream of nitrogen and immediately add the solvent of choice.

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