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ALX-380-299 Revised 29-Jul-08 New product
Prulifloxacin
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SYNONYMS 6-Fluoro-1-methyl-7-[4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]-1-piperazinyl]-4-oxo-1H,4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid
NM441
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-380-299-M250   250 mg 90.00 USD Add To Cart
ALX-380-299-G001   1 g 270.00 USD Add To Cart
Product Specification
FORMULA: C21H20FN3O6S
MW: 461.5
CAS NUMBER: 123447-62-1
MERCK INDEX: 14: 7908
PURITY: ≥98% (Assay)
APPEARANCE: White to yellow crystalline solid.
SOLUBILITY: Slightly soluble in dimethyl formamide, 0.1M NaOH or glacial acetic acid; insoluble in water or methanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C

Product Description
Fluoroquinolone with broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria.
Product Specific Literature References
In vivo evaluation of NM441, a new thiazeto-quinoline derivative: M. Ozaki, et al.; Antimicrob. Agents Chemother. 35, 2496 (1991) Abstract; Full Text
Studies on pyridonecarboxylic acids. 1. Synthesis and antibacterial evaluation of 7-substituted-6-halo-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3- carboxylic acids: J. Segawa, et al.; J. Med. Chem. 35, 4727 (1992) Abstract
Pharmacokinetics and safety of NM441, a new quinolone, in healthy male volunteers: M. Nakashima, et al.; J. Clin. Pharmacol. 34, 930 (1994) Abstract
Randomized, double-blind study of prulifloxacin versus ciprofloxacin in patients with acute exacerbations of chronic bronchitis: C. Grassi, et al.; Respiration 69, 217 (2002) Abstract; Full Text
Pharmacologic characteristics of prulifloxacin: M.G. Matera; Pulm. Pharmacol. Ther. 19, 20 (2006) Abstract
Prulifloxacin: a new fluoroquinolone for the treatment of acute exacerbation of chronic bronchitis: M. Cazzola, et al.; Pulm. Pharmacol. Ther. 19, 30 (2006) Abstract
Prulifloxacin: a new antibacterial fluoroquinolone: G. Prats, et al.; Expert. Rev. Anti. Infect. Ther. 4, 27 (2006), (Review) Abstract
Further Categories Containing This Product:
Antibiotics - Topoisomerase Inhibitors • Antibiotics - DNA Replication Inhibitors
 
 
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