ALEXIS Biochemicals: Reveromycin C

ALX-380-218

Revised 08-Apr-08

Reveromycin C
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antibiotics for Cell Cycle Research

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-218-MC25		0.25 mg	320.00 USD

Product Specification

FORMULA:	C₃₇H₅₄O₁₁
MW:	674.8
CAS NUMBER:	144860-69-5
SOURCE/HOST:	Isolated from Streptomyces sp. MST-AS5344.
PURITY:	≥95% (HPLC)
APPEARANCE:	White to tan solid.
SOLUBILITY:	Soluble in ethyl acetate, 100% ethanol, methanol, dimethyl formamide or DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Unstable in acidic conditions.

Product Description

Antibiotic. Minor component of the reveromycin complex with similar biological profile as reveromycin A (Prod. No. ALX-380-216), which is a G1 phase cell cycle inhibitor and induces apoptosis in osteoclasts. Generally more potent than reveromycin A. Inhibitor of the mitogenic activity of epidermal growth factor (EGF).

Product Specific Literature References

Reveromycins, new inhibitors of eukaryotic cell growth. I. Producing organism, fermentation, isolation and physico-chemical properties: H. Takahashi, et al.; J. Antibiot. (Tokyo) 45, 1409 (1992) Abstract
Reveromycins, new inhibitors of eukaryotic cell growth. II. Biological activities: H. Takahashi, et al.; J. Antibiot. (Tokyo) 45, 1414 (1992) Abstract

Further Categories Containing This Product:

Antibiotics - Apoptosis Inducers & Inhibitors • Bone Metabolism Other Products • EGFR Kinase Inhibitors • Cell Cycle Blockers & Inhibitors / Related Products • Antibiotics - Antifungal

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