ALEXIS Biochemicals: Roquefortine C

ALX-350-342

Revised 18-Apr-08

Roquefortine C
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Neurotoxins

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-342-MC05		0.5 mg	320.00 USD

Product Specification

FORMULA:	C₂₂H₂₃N₅O₂
MW:	389.5
CAS NUMBER:	58735-64-1
RTECS:	UQ4730500
SOURCE/HOST:	Isolated from Gymnoascus reesii MST-FP1700.
PURITY:	≥95% (HPLC)
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HAZARD:	TOXIC.

Product Description

Potent neurotoxin produced by a diverse range of fungi, most notably Penicillium species. Inhibits growth of Gram-positive bacteria. Inhibits cytochrome p450.

Product Specific Literature References

Isolation of festuclavine and three new indole alkaloids, roquefortine A, B and C from the cultures of Penicillium roqueforti: S. Ohmomo, et al.; Agric. Biol. Chem. 39, 1333 (1975)
Antimicrobial action of roquefortine: B. Kopp-Holtwiesche and H.J. Rehm; J. Environ. Pathol. Toxicol. Oncol. 10, 41 (1990) Abstract
Molecular requirements for inhibition of cytochrome p450 activities by roquefortine: C. Aninat, et al.; Chem. Res. Toxicol. 14, 1259 (2001) Abstract
Inhibitory effects of roquefortine on hepatic cytochromes P450: C. Aninat and M. Delaforge; Adv. Exp. Med. Biol. 500, 331 (2001) Abstract
The effects of the Penicillium mycotoxins citrinin, cyclopiazonic acid, ochratoxin A, patulin, penicillic acid, and roquefortine C on in vitro proliferation of porcine lymphocytes: M. Keblys, et al.; Mycopathologia 158, 317 (2004) Abstract

Further Categories Containing This Product:

Cytochrome P450 [CYP450]/Related Products • Mycotoxins • Alkaloids

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