ALEXIS Biochemicals: SANT-2

ALX-270-436

Revised 12-Aug-08

SANT-2
SYNONYMS	N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Hedgehog [Hh] Signalling Pathway

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-436-M001		1 mg	165.00 USD

Product Specification

FORMULA:	C₂₆H₂₆ClN₃O₄
MW:	480.0
CAS NUMBER:	329196-48-7
PURITY:	≥95%
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 6 months when stored at -20°C in the dark.
HANDLING:	Protect from light.
IDENTITY:	Identity determined by ¹H-NMR, ¹³C-NMR and MS.

Product Description

Cell permeable antagonist of the Smoothened (Smo) protein function. Inhibitor of SAG (Prod. No. ALX-270-426) activity. Chemical tool to study the Hedgehog (Hh) signalling pathway and to explore therapeutic uses for inhibitors of Smo.

Product Specific Literature References

Small molecule modulation of Smoothened activity: J.K. Chen, et al.; PNAS 99, 14071 (2002) Abstract; Full Text

another CS2 website

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