ALEXIS Biochemicals: Sarafloxacin . hydrochloride

ALX-380-301

Revised 04-Aug-08

Sarafloxacin . hydrochloride
SYNONYMS	6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid . hydrochloride A-56620

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-301-G005		5 g	50.00 USD
ALX-380-301-G025		25 g	150.00 USD

Product Specification

FORMULA:	C₂₀H₁₇F₂N₃O₃ . HCl
MW:	385.4 . 36.5
CAS NUMBER:	91296-87-6
MERCK INDEX:	14: 8370
PURITY:	≥98% (Assay)
APPEARANCE:	White to yellow crystalline solid.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
IDENTITY:	Identity determined by IR.

Product Description

Fluoroquinolone antibacterial agent. Inhibits bacterial DNA gyrase (topoisomerase). Effective against Mycobacterium tuberculosis.

Product Specific Literature References

Synthesis and structure-activity relationships of novel arylfluoroquinolone antibacterial agents: D.T. Chu, et al.; J. Med. Chem. 28, 1558 (1985) Abstract
In vivo evaluation of A-56619 (difloxacin) and A-56620: new aryl-fluoroquinolones: P.B. Fernandes, et al.; Antimicrob. Agents Chemother. 29, 201 (1986) Abstract; Full Text
In-vitro activity of six fluorinated quinolones against Mycobacterium tuberculosis: O.G. Berlin, et al.; J. Antimicrob. Chemother. 19, 611 (1987) Abstract
In vitro activities of A-56619 (difloxacin) and A-56620, two aryl fluoroquinolones: A. Digranes & W.L. Dibb; Chemotherapy 34, 298 (1988) Abstract
Determination of temafloxacin, sarafloxacin, and difloxacin in bulk drug and dosage forms by high-performance liquid chromatography: J.F. Bauer, et al.; Pharm. Res. 7, 1177 (1990) Abstract

Further Categories Containing This Product:

Antibiotics - Topoisomerase Inhibitors • Antibiotics - DNA Replication Inhibitors

another CS2 website

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.