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ALX-151-014
Revised 15-Dec-04
cAMP-dependent Protein Kinase Inhibitor (5-24)
SYNONYMS
PKA Inhibitor (5-24)
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKA Inhibitors
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-014-MC05
0.5 mg
90.00 USD
ALX-151-014-M001
1 mg
160.00 USD
Product Specification
SEQUENCE:
H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH
FORMULA:
C
94
H
148
N
32
O
31
MW:
2222.4
PURITY:
≥97%
APPEARANCE:
White to off-white powder.
FORMULATION:
Lyophilized.
SOLUBILITY:
Soluble in water or 5 % acetic acid.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Keep cool and dry.
Product Description
Potent inhibitor of cAMP-dependent protein kinase (PKA). The peptide corresponds to the active site of the skeletal muscle inhibitor protein.
Product Specific Literature References
A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase:
H.-C. Cheng, et al.; J. Biol. Chem.
261
, 989 (1986)
Abstract
;
Full Text
Phosphorylation of Avena phytochrome in vitro as a probe of light- induced conformational changes:
Y.S. Wong, et al.; J. Biol. Chem.
261
, 12089 (1986)
Abstract
;
Full Text
Further Categories Containing This Product:
Peptides
ALX-151-016
Revised 17-Jan-05
cAMP-dependent Protein Kinase Inhibitor (5-22) amide
SYNONYMS
PKA Inhibitor (5-22) amide
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKA Inhibitors
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-016-MC05
0.5 mg
110.00 USD
ALX-151-016-M001
1 mg
180.00 USD
Product Specification
SEQUENCE:
H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH
2
FORMULA:
C
84
H
137
N
29
O
26
MW:
1969.2
PURITY:
≥97%
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Potent inhibitor of cAMP-dependent protein kinase (PKA).
Product Specific Literature References
A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase:
H.-C. Cheng, et al.; J. Biol. Chem.
261
, 989 (1986)
Abstract
;
Full Text
Primary structural determinants essential for potent inhibition of cAMP- dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein:
D.B. Glass, et al.; J. Biol. Chem.
264
, 8802 (1989)
Abstract
;
Full Text
Further Categories Containing This Product:
Peptides
ALX-151-017
Revised 15-Dec-04
cAMP-dependent Protein Kinase Inhibitor (14-24) amide
SYNONYMS
PKA Inhibitor (14-24) amide
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKA Inhibitors
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-017-M001
1 mg
90.00 USD
ALX-151-017-M005
5 mg
360.00 USD
Product Specification
SEQUENCE:
H-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-NH
2
FORMULA:
C
49
H
86
N
24
O
15
MW:
1251.4
PURITY:
≥97%
APPEARANCE:
White powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Further Categories Containing This Product:
Peptides
ALX-151-018
Revised 13-Feb-06
cAMP-dependent Protein Kinase Inhibitor (5-24) amide
SYNONYMS
PKA Inhibitor (5-24) amide
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKA Inhibitors
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-018-MC05
0.5 mg
90.00 USD
ALX-151-018-M001
1 mg
160.00 USD
Product Specification
SEQUENCE:
H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-NH
2
FORMULA:
C
94
H
149
N
33
O
30
MW:
2221.4
PURITY:
≥97%
APPEARANCE:
White to off-white lyophilized powder.
SOLUBILITY:
Soluble in water or DMSO.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Specific Literature References
A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase:
H.-C. Cheng, et al.; J. Biol. Chem.
261
, 989 (1986)
Abstract
;
Full Text
Further Categories Containing This Product:
Peptides
ALX-151-019
Revised 15-Dec-04
cAMP-dependent Protein Kinase Substrate
SYNONYMS
PKA Substrate
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKA Substrates
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-019-MC05
0.5 mg
95.00 USD
ALX-151-019-M001
1 mg
165.00 USD
Product Specification
SEQUENCE:
H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH
FORMULA:
C
92
H
150
N
28
O
29
MW:
2112.4
PURITY:
≥95%
APPEARANCE:
White powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Derived from the RII subunit of cAMP-dependent protein kinase (PKA). Substrate for PKA. Has been used in a non-radioactive assay of calcineurin (protein phosphatase 2B) for screening purposes.
Product Specific Literature References
Dephosphorylation of cAMP-dependent protein kinase regulatory subunit (type II) by calmodulin-dependent protein phosphatase. Determinants of substrate specificity:
D.K. Blumenthal, et al.; J. Biol. Chem.
261
, 8140 (1986)
Abstract
;
Full Text
Nonradioactive assay for protein phosphatase 2B (calcineurin) activity using a partial sequence of the subunit of cAMP-dependent protein kinase as substrate:
A. Enz, et al.; Anal. Biochem.
216
, 147 (1994)
Abstract
Further Categories Containing This Product:
PP2B [Calcineurin] / Related Products
•
Peptides
ALX-151-021
Revised 14-Aug-02
H-Arg-Gly-Tyr-Ser-Leu-Gly-OH
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKA Inhibitors
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-021-M001
1 mg
40.00 USD
ALX-151-021-M005
5 mg
140.00 USD
Product Specification
FORMULA:
C
28
H
45
N
9
O
9
MW:
651.7
PURITY:
≥97%
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Substrate for cAMP-dependent protein kinase (PKA).
Product Specific Literature References
Synthetic hexapeptide substrates and inhibitors of 3':5'-cyclic AMP- dependent protein kinase:
B.E. Kemp, et al.; PNAS
73
, 1038 (1976)
Abstract
Synthetic peptide substrates of the cAMP-dependent protein kinase:
B.E. Kemp, et al.; Fed. Proc.
35
, 1384 (1976)
Further Categories Containing This Product:
Peptides
ALX-151-022
Revised 14-Aug-02
H-Arg-Gly-Tyr-Ala-Leu-Gly-OH
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKA Substrates
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-022-M001
1 mg
40.00 USD
ALX-151-022-M005
5 mg
140.00 USD
Product Specification
FORMULA:
C
28
H
45
N
9
O
8
MW:
635.7
PURITY:
≥97%
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Competitive inhibitor of cAMP-dependent protein kinase (PKA).
Product Specific Literature References
Synthetic hexapeptide substrates and inhibitors of 3':5'-cyclic AMP- dependent protein kinase:
B.E. Kemp, et al.; PNAS
73
, 1038 (1976)
Abstract
Further Categories Containing This Product:
Peptides
ALX-157-014
Revised 14-Dec-04
H-Gly-Arg-Gly-Leu-Ser-Leu-Ser-Arg-OH
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKA Substrates
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-157-014-M001
1 mg
50.00 USD
ALX-157-014-M005
5 mg
200.00 USD
Product Specification
FORMULA:
C
34
H
64
N
14
O
11
MW:
845.0
PURITY:
≥98%
APPEARANCE:
White lyophilized powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Substrate for cAMP-dependent protein kinase (PKA). The peptide corresponds to the amino acid sequence 106-113 of the human myelin basic protein.
Product Specific Literature References
Synthetic substrate for cyclic AMP-dependent protein kinase:
P. Daile, et al.; Nature
257
, 416 (1975)
Abstract
Further Categories Containing This Product:
Peptides
ALX-158-001
Revised 28-Feb-06
Histone H1-7 Substrate
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Histones / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-158-001-M001
1 mg
70.00 USD
ALX-158-001-M005
5 mg
280.00 USD
Product Specification
SEQUENCE:
H-Arg-Arg-Lys-Ala-Ser-Gly-Pro-OH
FORMULA:
C
31
H
58
N
14
O
9
MW:
770.9
PURITY:
≥98%
APPEARANCE:
White lyophilized powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Substrate for cAMP-dependent protein kinase (PKA). The peptide is derived from the phosphorylation site (Ser
38
) in calf thymus histone H1.
Product Specific Literature References
Studies on the mechanism of phosphorylation of synthetic polypeptides by a calf thymus cyclic AMP-dependent protein kinase:
A.H. Pomerantz, et al.; PNAS
74
, 4261 (1977)
Abstract
Further Categories Containing This Product:
Peptides
•
PKA Substrates
ALX-160-002
Revised 18-Dec-02
Kemptamide
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKA Substrates
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-160-002-M001
1 mg
50.00 USD
ALX-160-002-M005
5 mg
200.00 USD
Product Specification
SEQUENCE:
H-Leu-Arg-Arg-Ala-Ser-Leu-Gly-NH
2
FORMULA:
C
32
H
62
N
14
O
8
MW:
770.9
PURITY:
≥97%
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Amide analog of Kemptide (Prod. No.
ALX-160-006
).
Further Categories Containing This Product:
Peptides
ALX-160-006
Revised 04-Feb-05
Kemptide
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKA Substrates
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-160-006-M001
1 mg
30.00 USD
ALX-160-006-M005
5 mg
90.00 USD
Product Specification
SEQUENCE:
H-Leu-Arg-Arg-Ala-Ser-Leu-Gly-OH
FORMULA:
C
32
H
61
N
13
O
9
MW:
771.9
CAS NUMBER:
65189-71-1
PURITY:
≥97%
APPEARANCE:
White lyophilized powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Phosphate acceptor peptide. Substrate for cAMP-dependent protein kinase (PKA). The sequence defines the phosphorylation site of porcine liver pyruvate kinase.
Product Specific Literature References
Synthetic peptide substrates of the cAMP-dependent protein kinase:
B.E. Kemp, et al.; Fed. Proc.
35
, 1384 (1976)
Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase:
B.E. Kemp, et al.; J. Biol. Chem.
252
, 4888 (1977)
Abstract
;
Full Text
Studies on the mechanism of phosphorylation of synthetic polypeptides by a calf thymus cyclic AMP-dependent protein kinase:
A.H. Pomerantz, et al.; PNAS
74
, 4261 (1977)
Abstract
Adrenergic control of the cyclic AMP-dependent protein kinase and pyruvate kinase in isolated hepatocytes. Application of a synthetic peptide substrate for measuring protein kinase activity:
B.E. Kemp & M.G. Clark; J. Biol. Chem.
253
, 5147 (1978)
Abstract
;
Full Text
In vivo phosphorylation of a synthetic peptide substrate of cyclic AMP- dependent protein kinase:
J.L. Maller, et al.; PNAS
75
, 248 (1978)
Abstract
Optimal spatial requirements for the location of basic residues in peptide substrates for the cyclic AMP-dependent protein kinase:
J.R. Feramisco, et al.; J. Biol. Chem.
255
, 4240 (1980)
Abstract
;
Full Text
Further Categories Containing This Product:
Peptides
ALX-160-008
Revised 13-Jan-05
[Trp4]-Kemptide
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKA Substrates
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-160-008-M001
1 mg
50.00 USD
ALX-160-008-M005
5 mg
200.00 USD
