• Home
  • Sitemap
  • Help
  • Technical Support
  • Contact
Calcium Signalling (Intracellular)
You are here: Product Lines > Signal Transduction > Calcium Signalling (Intracellular)
 
Toolbar - View Selection
 
 Items 140-160 of 193 Page 8 of 10 Select Page: << 1 2 3 4 5 6 7 8 9 10  >>  
ALX-163-003 Revised 06-Jun-03
NPY (human)
Add to Clipboard
SYNONYMS Neuropeptide Y (human)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Ca2+ Modulators
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-163-003-PC05   0.5 mg* 140.00 USD Add To Cart
ALX-163-003-P001   1 mg* 250.00 USD Add To Cart
Product Specification
SEQUENCE: H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
FORMULA: C189H285N55O57S
MW: 4271.7
CAS NUMBER: 90880-35-6
MERCK INDEX: 14: 6485
QUANTITY: *Sold as net peptide weight.
PURITY: ≥97%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Specific Literature References
Cloning, characterization, and DNA sequence of a human cDNA encoding neuropeptide tyrosine: C.D. Minth, et al.; PNAS 81, 4577 (1984) Abstract
Further Categories Containing This Product:
Leptin / Related Products • Peptides • Neuropeptides & Receptors Other Products
 
 
ALX-153-009 Revised 20-Sep-05
Ca2+/Calmodulin-dependent Protein Kinase II (281-289)
Add to Clipboard
SYNONYMS CaM Kinase II (281-289)
CAMK2 (281-289)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY CAM Kinases
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-153-009-M001   1 mg 70.00 USD Add To Cart
ALX-153-009-M005   5 mg 280.00 USD Add To Cart
Product Specification
SEQUENCE: H-Met-His-Arg-Gln-Glu-Thr-Val-Asp-Cys-OH
FORMULA: C43H71N15O16S2
MW: 1118.3
PURITY: ≥97%
APPEARANCE: White lyophilized powder.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Amino acid sequence defining the major Ca2+-dependent autophosphorylation site of Ca2+/calmodulin-dependent protein kinase II.
Product Specific Literature References
Regulatory interactions of the calmodulin-binding, inhibitory, and autophosphorylation domains of Ca2+/calmodulin-dependent protein kinase II: R.J. Colbran, et al.; J. Biol. Chem. 263, 18145 (1988) Abstract; Full Text
Functional determinants in the autoinhibitory domain of calcium/calmodulin-dependent protein kinase II. Role of His282 and multiple basic residues: M.K. Smith, et al.; J. Biol. Chem. 267, 1761 (1992) Abstract; Full Text
Ca2+/calmodulin-dependent protein kinase II is phosphorylated by protein kinase C in vitro: M.N. Waxham & J. Aronowski; Biochemistry 32, 2923 (1993) Abstract
Further Categories Containing This Product:
Peptides
 
 
ALX-153-018 Revised 16-Feb-05
[Ala288]-Ca2+/Calmodulin-dependent Protein Kinase II (281-289)
Add to Clipboard
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY CAM Kinases
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-153-018-M005   5 mg 60.00 USD Add To Cart
Product Specification
SEQUENCE: H-Met-His-Arg-Gln-Glu-Thr-Val-Ala-Cys-OH
FORMULA: C42H71N15O14S2
MW: 1074.3
PURITY: ≥97%
APPEARANCE: Lyophilized powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Further Categories Containing This Product:
Peptides
 
 
ALX-151-029 Revised 23-Nov-06
Autocamtide-2-Related Inhibitory Peptide
Add to Clipboard
SYNONYMS AIP
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY CAM Kinase Inhibitors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-151-029-M001   1 mg 75.00 USD Add To Cart
ALX-151-029-M005   5 mg 300.00 USD Add To Cart
Product Specification
SEQUENCE: H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH
FORMULA: C64H116N22O19
MW: 1497.8
PURITY: ≥98%
APPEARANCE: Lyophilized.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Highly specific and potent inhibitor of Ca2+/calmodulin-dependent protein kinase II without affecting cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and Ca2+/calmodulin-dependent protein kinase IV.
Product Specific Literature References
A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II: A. Ishida, et al.; BBRC 212, 806 (1995) Abstract
Stabilization of calmodulin-dependent protein kinase II through the autoinhibitory domain: A. Ishida & H. Fujisawa; J. Biol. Chem. 270, 2163 (1995) Abstract; Full Text
Further Categories Containing This Product:
Peptides
 
 
ALX-151-030 Revised 05-Feb-08
Autocamtide-2-Related Inhibitory Peptide (Myristoylated)
Add to Clipboard
SYNONYMS AIP Myristoylated
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY CAM Kinase Inhibitors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-151-030-MC05   0.5 mg 90.00 USD Add To Cart
Product Specification
SEQUENCE: Myr-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH
FORMULA: C78H142N22O20
MW: 1708.1
PURITY: ≥98%
APPEARANCE: Lyophilized.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Corresponds to Prod. No. ALX-151-029 but this one is N-terminal myristoylated to increase cell permeability.
Further Categories Containing This Product:
Peptides
 
 
ALX-153-006 Revised 20-Sep-05
Ca2+/Calmodulin-dependent Protein Kinase II (290-309)
Add to Clipboard
SYNONYMS CaM Kinase II (290-309)
CAMK2 (290-309)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY CAM Kinase Inhibitors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-153-006-MC01   0.1 mg 40.00 USD Add To Cart
ALX-153-006-M001   1 mg 120.00 USD Add To Cart
Product Specification
SEQUENCE: H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH
FORMULA: C103H185N31O24S
MW: 2273.9
PURITY: ≥98%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Potent inhibitor of Ca2+/calmodulin-dependent protein kinase II.
Product Specific Literature References
Calcium/calmodulin-dependent protein kinase II. Characterization of distinct calmodulin binding and inhibitory domains: M.E. Payne, et al.; J. Biol. Chem. 263, 7190 (1988) Abstract; Full Text
Further Categories Containing This Product:
Peptides
 
 
ALX-153-010 Revised 16-Feb-05
[Ala286]-Ca2+/Calmodulin-dependent Protein Kinase II (281-302)
Add to Clipboard
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY CAM Kinase Inhibitors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-153-010-MC01   0.1 mg 50.00 USD Add To Cart
ALX-153-010-M001   1 mg 190.00 USD Add To Cart
Product Specification
SEQUENCE: H-Met-His-Arg-Gln-Glu-Ala-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-OH
FORMULA: C111H191N39O29S2
MW: 2600.1
PURITY: ≥97%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Inhibitor of Ca2+/calmodulin-dependent protein kinase II catalytic fragment, competitive with ATP. The sequence for this product matches that of the original article describing this "CaM kinase II inhibitor" peptide.
Product Specific Literature References
Functional determinants in the autoinhibitory domain of calcium/calmodulin-dependent protein kinase II. Role of His282 and multiple basic residues: M.K. Smith, et al.; J. Biol. Chem. 267, 1761 (1992) Abstract; Full Text
Further Categories Containing This Product:
Peptides
 
 
ALX-151-023 Revised 23-Nov-06
Autocamtide-2
Add to Clipboard
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY CAM Kinase Substrates
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-151-023-M001   1 mg 80.00 USD Add To Cart
ALX-151-023-M005   5 mg 320.00 USD Add To Cart
Product Specification
SEQUENCE: H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-OH
FORMULA: C65H118N22O20
MW: 1527.8
PURITY: ≥98%
APPEARANCE: Lyophilized.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Very selective substrate for Ca2+/calmodulin-dependent protein kinase II.
Product Specific Literature References
Expression of a multifunctional Ca2+/calmodulin-dependent protein kinase and mutational analysis of its autoregulation: P.I. Hanson, et al.; Neuron 3, 59 (1989) Abstract
Further Categories Containing This Product:
Peptides
 
 
ALX-153-008 Revised 20-Sep-05
Ca2+/Calmodulin-dependent Protein Kinase IV Substrate
Add to Clipboard
SYNONYMS CaM Kinase IV Substrate
CAMK4 Substrate
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY CAM Kinase Substrates
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-153-008-M001   1 mg 70.00 USD Add To Cart
ALX-153-008-M005   5 mg 290.00 USD Add To Cart
Product Specification
SEQUENCE: H-Lys-Ser-Asp-Gly-Gly-Val-Lys-Lys-Arg-Lys-Ser-Ser-Ser-Ser-OH
FORMULA: C58H107N21O22
MW: 1450.6
PURITY: ≥98%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Very selective and potent substrate for a brain-specific Ca2+/calmodulin-dependent protein kinase IV over Ca2+/calmodulin-dependent protein kinase II. This peptide corresponds to aa 345-358 of Ca2+/calmodulin-dependent protein kinase II-δ.
Product Specific Literature References
Purification and characterization of a brain-specific multifunctional calmodulin-dependent protein kinase from rat cerebellum: O. Miyano, et al.; J. Biol. Chem. 267, 1198 (1992) Abstract; Full Text
Further Categories Containing This Product:
Peptides
 
 
ALX-167-007 Revised 12-Jun-03
Syntide 2
Add to Clipboard
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY CAM Kinase Substrates
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-167-007-M001   1 mg 70.00 USD Add To Cart
ALX-167-007-M005   5 mg 280.00 USD Add To Cart
Product Specification
SEQUENCE: H-Pro-Leu-Ala-Arg-Thr-Leu-Ser-Val-Ala-Gly-Leu-Pro-Gly-Lys-Lys-OH
FORMULA: C68H122N20O18
MW: 1507.8
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Substrate for Ca2+/calmodulin-dependent protein kinase II and protein kinase C (PKC). The peptide sequence is homologous to the phosphorylation site 2 in glycogen synthase.
Product Specific Literature References
Calcium . calmodulin-dependent protein kinase II and calcium . phospholipid-dependent protein kinase activities in rat tissues assayed with a synthetic peptide: Y. Hashimoto & T.R. Soderling; Arch. Biochem. Biophys. 252, 418 (1987) Abstract
Further Categories Containing This Product:
Peptides • PKC Substrates
 
 
ALX-450-012 Revised 24-Oct-07
Valinomycin
Add to Clipboard
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Antibiotics - Ionophores
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-450-012-M005   5 mg 20.00 USD Add To Cart
ALX-450-012-M025   25 mg 60.00 USD Add To Cart
Product Specification
FORMULA: C54H90N6O18
MW: 1111.4
CAS NUMBER: 2001-95-8
MERCK INDEX: 14: 9910
SOURCE/HOST: Isolated from Streptomyces fulvissimus.
PURITY: ≥90%
APPEARANCE: White solid.
SOLUBILITY: Soluble in acetic acid, chloroform, DMSO or ether.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HAZARD: TOXIC.

Product Description
Potassium ionophore. Useful reagent for the measurement of K+ ions by electrode-based systems. Induces apoptosis in several cell lines.
Product Specific Literature References
Opposing interactions of ionophores (valinomycin and monensin) on calcium ion uptake in rat retinal preparations: J.B. Lombardini; Neurochem. Res. 10, 77 (1985) Abstract
Valinomycin-based K+ selective microelectrodes with low electrical membrane resistance: D. Ammann, et al.; Neurosci. Lett. 74, 221 (1987) Abstract
Alternative pathways of apoptosis induced by methylprednisolone and valinomycin analyzed by flow cytometry: C.L. Deckers, et al.; Exp. Cell. Res. 208, 362 (1993) Abstract
K+ ionophores inhibit nerve growth factor-induced neuronal differentiation in rat adrenal pheochromocytoma PC12 cells: H.Harada, et al.; Biochim. Biophys. Acta 1220, 310 (1994) Abstract
The effect of respiration on the permeability of the mitochondrial membrane to ions: S. Luvisetto, et al.; Biochim. Biophys. Acta 1186, 12 (1994) Abstract
Combination of the electrogenic ionophores, valinomycin and CCCP, can lead to non-electrogenic K+/H+ exchange on bilayer lipid membranes: V.N. Orlov, et al.; FEBS Lett. 345, 104 (1994) Abstract
Valinomycin induces apoptosis of ascites hepatoma cells (AH-130) in relation to mitochondrial membrane potential: Y. Inai, et al.; Cell Struct. Funct. 22, 555 (1997) Abstract
Induction of apoptosis by valinomycin: mitochondrial permeability transition causes intracellular acidification: I.J. Furlong, et al.; Cell Death Differ 5, 214 (1998) Abstract
Valinomycin-induced apoptosis of human NK cells is predominantly caspase independent: A. Paananen, et al.; Toxicology 212, 37 (2005) Abstract
Further Categories Containing This Product:
Antibiotics - Apoptosis Inducers & Inhibitors
 
 
ALX-200-005 Revised 12-Apr-07
Calmodulin (human brain) (high purity)