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G-Protein Coupled Receptor Signalling
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ALX-804-647 Revised 13-Oct-06
Monoclonal Antibody to Bradykinin (MBK3)
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PRODUCT LINE Neurobiology
PRODUCT CATEGORY Bradykinin Receptor / Related Products
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ALX-804-647-R100   100 µl 210.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
CLONE: MBK3
ISOTYPE: Mouse IgG1
FORMULATION: Liquid. Undiluted ascites.
IMMUNOGEN: Bradykinin (H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH).
SPECIFICITY: Recognizes bradykinin from various species.
APPLICATION: Western Blot (1:1’000-1:4’000)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Anti-idiotypic antibodies bearing the internal image of a bradykinin epitope. Production, characterization, and interaction with the kinin receptor: M. Haasemann, et al.; J. Immunol. 147, 3882 (1991) Abstract
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ALX-804-489 Revised 02-Jun-05
Monoclonal Antibody to CCL1 (human) (8P16-N4-L21)
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SYNONYMS anti-I-309 (human) MAb (8P16-N4-L21)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY CC Chemokines & Receptors / Related Products
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ALX-804-489-C100   100 µg 220.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 8P16-N4-L21
ISOTYPE: Mouse IgM
CONCENTRATION: 1mg/ml
PURITY DETAIL: DEAE purified.
FORMULATION: Liquid. In PBS.
IMMUNOGEN: Recombinant human CCL1 (I-309).
SPECIFICITY: Recognizes human CCL1.
APPLICATION: Immunohistochemistry (frozen sections (5µg/ml))
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-594 Revised 10-Jun-05
Monoclonal Antibody to CCL2 (human) (5J.1)
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SYNONYMS anti-MCP-1 (human) MAb (5J.1)
anti-Monocyte Chemotactic Protein-1 (human) MAb (5J.1)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY CC Chemokines & Receptors / Related Products
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ALX-804-594-C100   100 µg 220.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 5J.1
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS.
IMMUNOGEN: Recombinant human CCL2 (monocyte chemotactic protein-1; MCP-1).
SPECIFICITY: Recognizes human CCL2.
APPLICATION: Immunohistochemistry (frozen sections (5µg/ml))
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-465 Revised 29-Feb-08
Monoclonal Antibody to CCL2 (human) (5D3-F7)
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SYNONYMS anti-MCP-1 (human) MAb (5D3-F7)
anti-Monocyte Chemotactic Protein-1 (human) MAb (5D3-F7)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY CC Chemokines & Receptors / Related Products
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ALX-804-465-C100   100 µg 350.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 5D3-F7
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml
FORMULATION: Liquid. Purified antibody in PBS containing 0.1% sodium azide.
IMMUNOGEN: Recombinant human CCL2 (monocyte chemotactic protein-1; MCP-1).
SPECIFICITY: Recognizes human CCL2.
APPLICATION: ELISA (capture)
Immunocytochemistry (1:1'000)
Immunohistochemistry (frozen sections, paraffin sections (1:250-1:500))
Immunoprecipitation
Western Blot (1:1'000)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
A new monoclonal antibody (5D3-F7) which recognizes human monocyte chemotactic protein-1 but not related chemokines. Development of a sandwich ELISA and in situ detection of producing cells: G. Peri, et al.; J. Immunol. Methods 174, 249 (1994) Abstract
Analysis of the Gene Expression Profile Activated by the CC Chemokine Ligand 5/RANTES and by Lipopolysaccharide in Human Monocytes: M. Locati, et al.; J. Immunol. 168, 3557 (2002) Full Text
Human Pancreatic Islets Produce and Secrete MCP-1/CCL2: Relevance in Human Islet Transplantation: L. Piemonti, et al.; Diabetes 51, 55 (2002) Full Text
 
 
ALX-804-549 Revised 29-Feb-08
Monoclonal Antibody to CCL2 (human) (D9)
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SYNONYMS anti-MCP-1 (human) MAb (D9)
anti-Monocyte Chemotactic Protein-1 (human) MAb (D9)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY CC Chemokines & Receptors / Related Products
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ALX-804-549-C100   100 µg 220.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: D9
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml
FORMULATION: Liquid. Protein G purified antibody in PBS.
IMMUNOGEN: Recombinant human CCL2 (monocyte chemotactic protein-1; MCP-1).
SPECIFICITY: Recognizes human CCL2.
APPLICATION: Immunoprecipitation
Western Blot (5µg/ml)
Functional Application (blocks CCL2 [MCP-1]; 2µg/ml)
Not recommended for immunohistochemistry.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-470 Revised 10-May-06
Monoclonal Antibody to CCL22 (human) (152/11)
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SYNONYMS anti-MDC (human) MAb (152/11)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY CC Chemokines & Receptors / Related Products
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ALX-804-470-C250   250 µg 540.00 USD Add To Cart
ALX-804-470E-C250 Peroxidase 250 µg 580.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 152/11
ISOTYPE: Rat IgG
CONCENTRATION: ALX-804-470: 2.3mg/ml
ALX-804-470E:  0.36mg/ml
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: ALX-804-470: Liquid. In PBS, pH 7.4.
ALX-804-470E: Liquid. In PBS, pH 7.4, containing 0.2% bronidox and 0.05% phenol.
IMMUNOGEN: Recombinant human CCL22 (macrophage-derived chemokine; MDC).
SPECIFICITY: Recognizes human CCL22.
APPLICATION: ALX-804-470: Western Blot (2-4µg/ml)
Detection Limit: 0.2µg/lane.
ALX-804-470E: ELISA (detection (1-2µ/ml))
Use microtiter plates coated with primary antibody (Prod. No. ALX-804-469, MAb to CCL22 (human) (349/6) at 20µg/ml in 0.05M carbonate/bicarbonate buffer, pH 9.6) to detect human fractalkine.
Detection Limit: ~60pg/ml.
Substrate: 0.26mg/ml tetramethyl benzydine and 0.01% hydrogen peroxide stabilized in 0.05M citrate buffer, pH 3.8.
SHIPPING: SHIPPED ON BLUE ICE
USE/STABILITY: ALX-804-470: Short Term Storage: +4°C. Long Term Storage: After opening, prepare aliquots and store at -20°C.
ALX-804-470E: Long Term Storage: +4°C.
HANDLING: For maximum product recovery after thawing, centrifuge the vial before opening the cap.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-469 Revised 07-May-08
Monoclonal Antibody to CCL22 (human) (349/6)
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SYNONYMS anti-MDC (human) MAb (349/6)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY CC Chemokines & Receptors / Related Products
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ALX-804-469-C250   250 µg 540.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 349/6
ISOTYPE: Rat IgG
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant human CCL22 (macrophage-derived chemokine; MDC).
SPECIFICITY: Recognizes human CCL22.
APPLICATION: ELISA (capture (20µg/ml))
Use microtiter plates coated with this antibody in 0.05M carbonate/bicarbonate buffer, pH 9.6, in combination with secondary antibody (Prod. No. ALX-804-470, MAb to CCL22 (human) (152/11)) at 1-2µg/ml to detect human MDC.
Detection Limit: ~40pg/ml.
Substrate: 0.26mg/ml tetramethyl benzydine and 0.01% hydrogen peroxide stabilized in 0.05M citrate buffer, pH 3.8.
Western Blot (1-2µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Preservative may be added for storage at +4°C.
HANDLING: For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-591 Revised 20-Nov-06
Monoclonal Antibody to CCR3 (human) (5E8)
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SYNONYMS anti-C-C Chemokine Receptor 3 (human) MAb (5E8)
anti-Eotaxin Receptor (human) MAb (5E8)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY CC Chemokines & Receptors / Related Products
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ALX-804-591-C100   100 µg 220.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 5E8
ISOTYPE: Mouse IgG2a
CONCENTRATION: 1mg/ml
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS.
IMMUNOGEN: L1.2 cells expressing human CCR3 (C-C Chemokine Receptor 3).
SPECIFICITY: Recognizes human CCR3.
APPLICATION: Flow Cytometry
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-472 Revised 10-Feb-05
Monoclonal Antibody to CX3CL1 (human) (20/20)
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SYNONYMS anti-Fractalkine (human) MAb (20/20)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY CX3C Chemokines & Receptors / Related Products
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ALX-804-472-C250   250 µg 540.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 20/20
ISOTYPE: Rat IgG
PURITY DETAIL: Purified by protein G affinity chromatography.
FORMULATION: Liquid. In PBS, pH 7.4.
IMMUNOGEN: Recombinant human CX3CL1 (fractalkine).
SPECIFICITY: Recognizes human CX3CL1.
APPLICATION: ELISA (detection (1-2µg/ml))
Upon conjugation with a suitable label this antibody can be used with primary antibody (Prod. No. ALX-804-471, MAb to CX3CL1 (human) (28/31) at 20µg/ml) to detect human fractalkine.
Detection Limit: ~0.5ng/ml.
Western Blot (1-2µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap. After opening, prepare aliquots and store at -20°C.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-471 Revised 05-Aug-05
Monoclonal Antibody to CX3CL1 (human) (28/31)
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SYNONYMS anti-Fractalkine (human) MAb (28/31)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY CX3C Chemokines & Receptors / Related Products
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ALX-804-471-C250   250 µg 540.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 28/31
ISOTYPE: Rat IgG
PURITY DETAIL: Purified by protein G affinity chromatography.
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant human CX3CL1 (fractalkine).
SPECIFICITY: Recognizes human CX3CL1.
APPLICATION: ELISA (capture (20µg/ml))
Use microtiter plates coated with this antibody in 0.05M carbonate/bicarbonate buffer, pH 9.6, in combination with secondary antibody (Prod. No. ALX-804-472, MAb to CX3CL1 (human) (20/20) at 1-2µg/ml to detect human fractalkine.
Detection Limit: ~1ng/ml.
Substrate: 0.26mg/ml tetramethyl benzydine and 0.01% hydrogen peroxide stabilized in 0.05M citrate buffer, pH 3.8.
Western Blot (2-4µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap. After opening, prepare aliquots and store at -20°C.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-803-047 Revised 07-Mar-06
Monoclonal Antibody to Proendothelin-1 (184-203) (human) (154/2A10)
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SYNONYMS anti-ProET-1 (184-203) (human) MAb (154/2A10)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Endothelins [ETs] & Endothelin Receptors / Related Products
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ALX-803-047-C100   100 µg 300.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 154/2A10
ISOTYPE: Mouse IgG1
CONCENTRATION: 0.5mg/ml
PURITY DETAIL: Ammonium sulphate precipitation.
FORMULATION: Liquid. In PBS, pH 7.4, containing 0.9mg/ml sodium azide.
IMMUNOGEN: Recombinant human proendothelin-1 aa 184-203 (CN184SVKSSFHDPKLKGKPSRER203).
SPECIFICITY: Recognizes an epitope (aa 184-203) of human proendothelin-1.
APPLICATION: ELISA
Radioimmunoassay
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year when stored at +4°C.
HANDLING: Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-803-046 Revised 07-Mar-06
Monoclonal Antibody to Proendothelin-1 (32-53) (human) (164/3F7)
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SYNONYMS anti-ProET-1 (32-53) (human) MAb (164/3F7)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Endothelins [ETs] & Endothelin Receptors / Related Products
Ordering Information
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ALX-803-046-C100   100 µg 300.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 164/3F7
ISOTYPE: Mouse IgG1
CONCENTRATION: 0.5mg/ml
PURITY DETAIL: Ammonium sulphate precipitation.
FORMULATION: Liquid. In PBS, pH 7.4, containing 0.9mg/ml sodium azide.
IMMUNOGEN: Recombinant human proendothelin-1 (G32ENGGEKPTPSPPWRLRRSKRC53).