• Home
  • Sitemap
  • Help
  • Technical Support
  • Contact
Diacylglycerol Kinases / Related Products
You are here: Product Lines > Signal Transduction > Lipid Signalling Pathways > Diacylglycerol Kinases / Related Products
Toolbar - View Selection
 
Items 2 of 2
ALX-430-027 Revised 05-Dec-04
Diacylglycerol Kinase Inhibitor I (R59 022)
Add to Clipboard
SYNONYMS 6-[2-(4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl)ethyl]-7-methyl-5H-thiazolo-[3,2-a]pyrimidine-5-one
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Diacylglycerol Kinases / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-430-027-M005   5 mg 115.00 USD Add To Cart
Product Specification
FORMULA: C27H26FN3OS
MW: 459.6
CAS NUMBER: 93076-89-2
PURITY: ≥99%
APPEARANCE: Yellow powder.
SOLUBILITY: Soluble in DMSO, THF or DMF. Insoluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C

Product Description
Potentiates the activity of protein kinase C (PKC) by inhibiting the diacylglycerol metabolism. Inhibits diacylglycerol kinase without affecting phosphodiesterase or phosphatidyl inositol kinase.
Product Specific Literature References
R 59 022, a diacylglycerol kinase inhibitor. Its effect on diacylglycerol and thrombin-induced C kinase activation in the intact platelet: D. de Chaffoy de Courcelles, et al.; J. Biol. Chem. 260, 15762 (1985) Abstract; Full Text
Further Categories Containing This Product:
PKC Activators
 
 
ALX-430-028 Revised 30-Oct-06
Diacylglycerol Kinase Inhibitor II (R59 949)
Add to Clipboard
SYNONYMS 3-[2-[4-[bis(4-Fluorophenyl)methylene]-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Diacylglycerol Kinases / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-430-028-M005   5 mg 90.00 USD Add To Cart
ALX-430-028-M025   25 mg 270.00 USD Add To Cart
Product Specification
FORMULA: C28H25F2N3OS
MW: 489.6
CAS NUMBER: 120166-69-0
PURITY: ≥98%
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in dichloromethane, ethyl acetate, tetrahydro-furan, DMSO or dimethyl formamide; almost insoluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C

Product Description
Inhibitor of diacylglycerol kinase. More potent analog of R59 022 (Prod. No. ALX-430-027). Useful for elucidating roles of protein kinase C (PKC).
Product Specific Literature References
R 59 022, a diacylglycerol kinase inhibitor. Its effect on diacylglycerol and thrombin-induced C kinase activation in the intact platelet: D. de Chaffoy de Courcelles, et al.; J. Biol. Chem. 260, 15762 (1985) Abstract; Full Text
The role of endogenously formed diacylglycerol in the propagation and termination of platelet activation. A biochemical and functional analysis using the novel diacylglycerol kinase inhibitor, R 59 949: D. de Chaffoy de Courcelles, et al.; J. Biol. Chem. 264, 3274 (1989) Abstract; Full Text
 
 
© 2008 ALEXIS Corporation, Privacy Policy, Disclaimer, Feedbackheader picture © micronaut.ch, another CS2 website

Catalogs / Brochures

E-Newsletter

 

Shopping Cart [0]

 

Distributors

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.