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PKA Substrates
You are here: Product Lines > Signal Transduction > cAMP Pathways > cAMP-dependent Protein Kinase [PKA] / Related Products > PKA Substrates
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ALX-151-019 Revised 15-Dec-04
cAMP-dependent Protein Kinase Substrate
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SYNONYMS PKA Substrate
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY PKA Substrates
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-151-019-MC05   0.5 mg 95.00 USD Add To Cart
ALX-151-019-M001   1 mg 165.00 USD Add To Cart
Product Specification
SEQUENCE: H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH
FORMULA: C92H150N28O29
MW: 2112.4
PURITY: ≥95%
APPEARANCE: White powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Derived from the RII subunit of cAMP-dependent protein kinase (PKA). Substrate for PKA. Has been used in a non-radioactive assay of calcineurin (protein phosphatase 2B) for screening purposes.
Product Specific Literature References
Dephosphorylation of cAMP-dependent protein kinase regulatory subunit (type II) by calmodulin-dependent protein phosphatase. Determinants of substrate specificity: D.K. Blumenthal, et al.; J. Biol. Chem. 261, 8140 (1986) Abstract; Full Text
Nonradioactive assay for protein phosphatase 2B (calcineurin) activity using a partial sequence of the subunit of cAMP-dependent protein kinase as substrate: A. Enz, et al.; Anal. Biochem. 216, 147 (1994) Abstract
Further Categories Containing This Product:
PP2B [Calcineurin] / Related Products • Peptides
 
 
ALX-151-022 Revised 14-Aug-02
H-Arg-Gly-Tyr-Ala-Leu-Gly-OH
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY PKA Substrates
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-151-022-M001   1 mg 40.00 USD Add To Cart
ALX-151-022-M005   5 mg 140.00 USD Add To Cart
Product Specification
FORMULA: C28H45N9O8
MW: 635.7
PURITY: ≥97%
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Competitive inhibitor of cAMP-dependent protein kinase (PKA).
Product Specific Literature References
Synthetic hexapeptide substrates and inhibitors of 3':5'-cyclic AMP- dependent protein kinase: B.E. Kemp, et al.; PNAS 73, 1038 (1976) Abstract
Further Categories Containing This Product:
Peptides
 
 
ALX-157-014 Revised 14-Dec-04
H-Gly-Arg-Gly-Leu-Ser-Leu-Ser-Arg-OH
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY PKA Substrates
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-157-014-M001   1 mg 50.00 USD Add To Cart
ALX-157-014-M005   5 mg 200.00 USD Add To Cart
Product Specification
FORMULA: C34H64N14O11
MW: 845.0
PURITY: ≥98%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Substrate for cAMP-dependent protein kinase (PKA). The peptide corresponds to the amino acid sequence 106-113 of the human myelin basic protein.
Product Specific Literature References
Synthetic substrate for cyclic AMP-dependent protein kinase: P. Daile, et al.; Nature 257, 416 (1975) Abstract
Further Categories Containing This Product:
Peptides
 
 
ALX-158-001 Revised 28-Feb-06
Histone H1-7 Substrate
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PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Histones / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-158-001-M001   1 mg 70.00 USD Add To Cart
ALX-158-001-M005   5 mg 280.00 USD Add To Cart
Product Specification
SEQUENCE: H-Arg-Arg-Lys-Ala-Ser-Gly-Pro-OH
FORMULA: C31H58N14O9
MW: 770.9
PURITY: ≥98%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Substrate for cAMP-dependent protein kinase (PKA). The peptide is derived from the phosphorylation site (Ser38) in calf thymus histone H1.
Product Specific Literature References
Studies on the mechanism of phosphorylation of synthetic polypeptides by a calf thymus cyclic AMP-dependent protein kinase: A.H. Pomerantz, et al.; PNAS 74, 4261 (1977) Abstract
Further Categories Containing This Product:
Peptides • PKA Substrates
 
 
ALX-160-002 Revised 18-Dec-02
Kemptamide
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY PKA Substrates
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ALX-160-002-M001   1 mg 50.00 USD Add To Cart
ALX-160-002-M005   5 mg 200.00 USD Add To Cart
Product Specification
SEQUENCE: H-Leu-Arg-Arg-Ala-Ser-Leu-Gly-NH2
FORMULA: C32H62N14O8
MW: 770.9
PURITY: ≥97%
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Amide analog of Kemptide (Prod. No. ALX-160-006).
Further Categories Containing This Product:
Peptides
 
 
ALX-160-006 Revised 04-Feb-05
Kemptide
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY PKA Substrates
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-160-006-M001   1 mg 30.00 USD Add To Cart
ALX-160-006-M005   5 mg 90.00 USD Add To Cart
Product Specification
SEQUENCE: H-Leu-Arg-Arg-Ala-Ser-Leu-Gly-OH
FORMULA: C32H61N13O9
MW: 771.9
CAS NUMBER: 65189-71-1
PURITY: ≥97%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Phosphate acceptor peptide. Substrate for cAMP-dependent protein kinase (PKA). The sequence defines the phosphorylation site of porcine liver pyruvate kinase.
Product Specific Literature References
Synthetic peptide substrates of the cAMP-dependent protein kinase: B.E. Kemp, et al.; Fed. Proc. 35, 1384 (1976)
Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase: B.E. Kemp, et al.; J. Biol. Chem. 252, 4888 (1977) Abstract; Full Text
Studies on the mechanism of phosphorylation of synthetic polypeptides by a calf thymus cyclic AMP-dependent protein kinase: A.H. Pomerantz, et al.; PNAS 74, 4261 (1977) Abstract
Adrenergic control of the cyclic AMP-dependent protein kinase and pyruvate kinase in isolated hepatocytes. Application of a synthetic peptide substrate for measuring protein kinase activity: B.E. Kemp & M.G. Clark; J. Biol. Chem. 253, 5147 (1978) Abstract; Full Text
In vivo phosphorylation of a synthetic peptide substrate of cyclic AMP- dependent protein kinase: J.L. Maller, et al.; PNAS 75, 248 (1978) Abstract
Optimal spatial requirements for the location of basic residues in peptide substrates for the cyclic AMP-dependent protein kinase: J.R. Feramisco, et al.; J. Biol. Chem. 255, 4240 (1980) Abstract; Full Text
Further Categories Containing This Product:
Peptides
 
 
ALX-160-008 Revised 13-Jan-05
[Trp4]-Kemptide
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY PKA Substrates
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-160-008-M001   1 mg 50.00 USD Add To Cart
ALX-160-008-M005   5 mg 200.00 USD Add To Cart
Product Specification
SEQUENCE: H-Leu-Arg-Arg-Trp-Ser-Leu-Gly-OH
FORMULA: C40H66N14O9
MW: 887.1
PURITY: ≥98%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Substrate for cAMP-dependent protein kinase (PKA). The phosphorylated product is an active substrate for phosphoprotein phosphatase.
Product Specific Literature References
Fluorometric assay for adenosine 3',5'-cyclic monophosphate-dependent protein kinase and phosphoprotein phosphatase activities: D.E. Wright, et al.; PNAS 78, 6048 (1981) Abstract
Further Categories Containing This Product:
Peptides
 
 
ALX-167-006 Revised 25-Feb-03
S6 Phosphate Acceptor Peptide
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY PKA Substrates
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-167-006-M001   1 mg 40.00 USD Add To Cart
ALX-167-006-M005   5 mg 160.00 USD Add To Cart
Product Specification
SEQUENCE: H-Arg-Arg-Leu-Ser-Ser-Leu-Arg-Ala-OH
FORMULA: C39H75N17O11
MW: 958.1
PURITY: ≥98%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Substrate for cAMP-dependent protein kinase (PKA) and for protein kinase C (PKC).
Product Specific Literature References
Phosphorylation of ribosomal protein S6 and a peptide analogue of S6 by a protease-activated kinase isolated from rat liver: B. Gabrielli, et al.; FEBS Lett. 175, 219 (1984) Abstract
Distinct structural requirements of Ca2+/phospholipid-dependent protein kinase (protein kinase C) and cAMP-dependent protein kinase as evidenced by synthetic peptide substrates: S. Ferrari, et al.; FEBS Lett. 184, 72 (1985) Abstract
Fibroblast growth factor treatment of Swiss 3T3 cells activates a subunit S6 kinase that phosphorylates a synthetic peptide substrate: S.L. Pelech, et al.; PNAS 83, 5968 (1986) Abstract
Further Categories Containing This Product:
Peptides • PKC Substrates
 
 
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