• Home
  • Sitemap
  • Help
  • Technical Support
  • Contact
CAM Kinase Substrates
You are here: Product Lines > Signal Transduction > CAM Kinase Substrates
Toolbar - View Selection
 
Items 7 of 7
ALX-151-023 Revised 23-Nov-06
Autocamtide-2
Add to Clipboard
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY CAM Kinase Substrates
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-151-023-M001   1 mg 80.00 USD Add To Cart
ALX-151-023-M005   5 mg 320.00 USD Add To Cart
Product Specification
SEQUENCE: H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-OH
FORMULA: C65H118N22O20
MW: 1527.8
PURITY: ≥98%
APPEARANCE: Lyophilized.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Very selective substrate for Ca2+/calmodulin-dependent protein kinase II.
Product Specific Literature References
Expression of a multifunctional Ca2+/calmodulin-dependent protein kinase and mutational analysis of its autoregulation: P.I. Hanson, et al.; Neuron 3, 59 (1989) Abstract
Further Categories Containing This Product:
Peptides
 
 
ALX-153-008 Revised 20-Sep-05
Ca2+/Calmodulin-dependent Protein Kinase IV Substrate
Add to Clipboard
SYNONYMS CaM Kinase IV Substrate
CAMK4 Substrate
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY CAM Kinase Substrates
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-153-008-M001   1 mg 70.00 USD Add To Cart
ALX-153-008-M005   5 mg 290.00 USD Add To Cart
Product Specification
SEQUENCE: H-Lys-Ser-Asp-Gly-Gly-Val-Lys-Lys-Arg-Lys-Ser-Ser-Ser-Ser-OH
FORMULA: C58H107N21O22
MW: 1450.6
PURITY: ≥98%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Very selective and potent substrate for a brain-specific Ca2+/calmodulin-dependent protein kinase IV over Ca2+/calmodulin-dependent protein kinase II. This peptide corresponds to aa 345-358 of Ca2+/calmodulin-dependent protein kinase II-δ.
Product Specific Literature References
Purification and characterization of a brain-specific multifunctional calmodulin-dependent protein kinase from rat cerebellum: O. Miyano, et al.; J. Biol. Chem. 267, 1198 (1992) Abstract; Full Text
Further Categories Containing This Product:
Peptides
 
 
ALX-167-007 Revised 12-Jun-03
Syntide 2
Add to Clipboard
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY CAM Kinase Substrates
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-167-007-M001   1 mg 70.00 USD Add To Cart
ALX-167-007-M005   5 mg 280.00 USD Add To Cart
Product Specification
SEQUENCE: H-Pro-Leu-Ala-Arg-Thr-Leu-Ser-Val-Ala-Gly-Leu-Pro-Gly-Lys-Lys-OH
FORMULA: C68H122N20O18
MW: 1507.8
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Substrate for Ca2+/calmodulin-dependent protein kinase II and protein kinase C (PKC). The peptide sequence is homologous to the phosphorylation site 2 in glycogen synthase.
Product Specific Literature References
Calcium . calmodulin-dependent protein kinase II and calcium . phospholipid-dependent protein kinase activities in rat tissues assayed with a synthetic peptide: Y. Hashimoto & T.R. Soderling; Arch. Biochem. Biophys. 252, 418 (1987) Abstract
Further Categories Containing This Product:
Peptides • PKC Substrates
 
 
ALX-200-606 Revised 08-May-08
Myelin Basic Protein (human) (high purity)
Add to Clipboard
SYNONYMS MBP (human) (high purity)
PRODUCT LINE Neurobiology
PRODUCT CATEGORY Myelin Basic Protein / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-200-606-M001   1 mg 350.00 USD Add To Cart
Product Specification
SOURCE/HOST: Purified from human brain by method of Määttä et al. [1].
CONCENTRATION: 1mg/ml after reconstitution.
PURITY: ≥95% (SDS-PAGE; Immunoblot)
APPEARANCE: White to off-white powder.
FORMULATION: Lyophilized. Essentially salt-free.
RECONSTITUTION: Reconstitute with distilled water.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year when stored at +4°C. Reconstituted protein is stable for at least six months at -20°C and for at least 24 hours at +37°C in aqueous solution.
Product Specific Literature References
[1] Detection of myelin basic protein isoforms by organic concentration: J.A. Määttä, et al.; BBRC 238, 498 (1997) Abstract
Interaction between the C-terminal region of human myelin basic protein and calmodulin: analysis of complex formation and solution structure: V. Majava, et al.; BMC Struct. Biol. 8, 10 (2008) Abstract; Full Text
General Information
MBP is a peripheral membrane protein, and its interaction with lipids is generally believed to be critical for the formation and stability of the multilamellar myelin sheath. It has been identified as a Ca2+-calmodulin regulated agent for actin polymerization, tropomyosin and actomyosin function, tubulin stabilization, and clathrin assembley. MBP is generally considered to be the antigen responsible for autoimmunity in multiple sclerosis (MS) and it has the capability to induce experimental allergic encephalomyelitis (EAE). MBP is also an endogenous inhibitor of the high-affinity cannabinoid binding site in the brain and a substrate for numerous protein kinases (MAPK, serine/threonine kinase, protein kinase C). MBP is also suggested to be involved in intracellular signalling and as cytoskeletal components.
Further Categories Containing This Product:
Natural Proteins • MAPK Pathway Substrates • CAM Kinase Substrates
 
 
ALX-202-075 Revised 20-Sep-06
Myelin Basic Protein (mouse) (high purity)
Add to Clipboard
SYNONYMS MBP (mouse) (high purity)
PRODUCT LINE Neurobiology
PRODUCT CATEGORY Myelin Basic Protein / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-202-075-M001   1 mg 120.00 USD Add To Cart
Product Specification
SOURCE/HOST: Purified from mouse central nervous system tissue by method of Määttä et al. [1].
PURITY: ≥95% (SDS-PAGE; immunoblot)
FORMULATION: Lyophilized. Essentially salt-free.
RECONSTITUTION: Reconstitute with distilled water.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year when stored at +4°C. Reconstituted protein is stable for at least six months at -20°C and for at least 24h at +37°C in aqueous solution.
Product Specific Literature References
[1] Detection of myelin basic protein isoforms by organic concentration: J.A. Määttä, et al.; BBRC 238, 498 (1997) Abstract
General Information
MBP is a peripheral membrane protein, and its interaction with lipids is generally believed to be critical for the formation and stability of the multilamellar myelin sheath. It has been identified as a Ca2+-calmodulin regulated agent for actin polymerization, tropomyosin and actomyosin function, tubulin stabilization, and clathrin assembley.
MBP is generally considered to be the antigen responsible for autoimmunity in multiple sclerosis (MS) and it has the capability to induce experimental allergic encephalomyelitis (EAE). MBP is also an endogenous inhibitor of the high-affinity cannabinoid binding site in the brain and a substrate for numerous protein kinases (MAPK, serine/threonine kinase, protein kinase C). MBP is also suggested to be involved in intracellular signalling and as cytoskeletal components.
Further Categories Containing This Product:
CAM Kinase Substrates • MAPK Pathway Substrates • Natural Proteins
 
 
ALX-202-076 Revised 04-Jul-07
Myelin Basic Protein (bovine) (high purity)
Add to Clipboard
SYNONYMS MBP (bovine) (high purity)
PRODUCT LINE Neurobiology
PRODUCT CATEGORY Myelin Basic Protein / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-202-076-M001   1 mg 30.00 USD Add To Cart
ALX-202-076-M005   5 mg 120.00 USD Add To Cart
ALX-202-076B-M001 Biotin 1 mg 180.00 USD Add To Cart
Product Specification
SOURCE/HOST: Purified from bovine central nervous system tissue by method of Määttä et al. [1].
PURITY: ≥95% (SDS-PAGE; immunoblot)
FORMULATION: Lyophilized. Essentially salt-free.
RECONSTITUTION: Reconstitute with distilled water.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year when stored at +4°C. Reconstituted protein is stable for at least 6 months at -20°C and for at least 24 hours at +37°C in aqueous solution.
Product Specific Literature References
[1] Detection of myelin basic protein isoforms by organic concentration: J.A. Määttä, et al.; BBRC 238, 498 (1997) Abstract
General Information
MBP is a peripheral membrane protein, and its interaction with lipids is generally believed to be critical for the formation and stability of the multilamellar myelin sheath. It has been identified as a Ca2+-calmodulin regulated agent for actin polymerization, tropomyosin and actomyosin function, tubulin stabilization, and clathrin assembley.
MBP is generally considered to be the antigen responsible for autoimmunity in multiple sclerosis (MS) and it has the capability to induce experimental allergic encephalomyelitis (EAE). MBP is also an endogenous inhibitor of the high-affinity cannabinoid binding site in the brain and a substrate for numerous protein kinases (MAPK, serine/threonine kinase, protein kinase C). MBP is also suggested to be involved in intracellular signalling and as cytoskeletal components.
Further Categories Containing This Product:
CAM Kinase Substrates • MAPK Pathway Substrates • Natural Proteins
 
 
ALX-202-077 Revised 22-Aug-06
Myelin Basic Protein (porcine) (high purity)
Add to Clipboard
SYNONYMS MBP (porcine) (high purity)
PRODUCT LINE Neurobiology
PRODUCT CATEGORY Myelin Basic Protein / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-202-077-M001   1 mg 35.00 USD Add To Cart
ALX-202-077-M005   5 mg 140.00 USD Add To Cart
Product Specification
SOURCE/HOST: Purified from porcine brain by method of Määttä et al. [1].
PURITY: ≥95% (SDS-PAGE; immunoblot)
FORMULATION: Lyophilized. Essentially salt-free.
RECONSTITUTION: Reconstitute with distilled water.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 3 years when stored at +4°C. Reconstituted protein is stable for at least six months at -20°C and for at least 24 hours at +37°C in aqueous solution.
Product Description
Passes activity test as a protein kinase substrate according to Courtney et al. [2].
Product Specific Literature References
[1] Detection of myelin basic protein isoforms by organic concentration: J.A. Määttä, et al.; BBRC 238, 498 (1997) Abstract
[2] Neurotrophins protect cultured cerebellar granule neurons against the early phase of cell death by a two-component mechanism: M.J. Courtney, et al.; J. Neurosci. 17, 4201 (1997) Abstract
General Information
MBP is a peripheral membrane protein, and its interaction with lipids is generally believed to be critical for the formation and stability of the multilamellar myelin sheath. It has been identified as a Ca2+-calmodulin regulated agent for actin polymerization, tropomyosin and actomyosin function, tubulin stabilization, and clathrin assembley.
MBP is generally considered to be the antigen responsible for autoimmunity in multiple sclerosis (MS) and it has the capability to induce experimental allergic encephalomyelitis (EAE). MBP is also an endogenous inhibitor of the high-affinity cannabinoid binding site in the brain and a substrate for numerous protein kinases (MAPK, serine/threonine kinase, protein kinase C). MBP is also suggested to be involved in intracellular signalling and as cytoskeletal components.
Further Categories Containing This Product:
CAM Kinase Substrates • MAPK Pathway Substrates • Natural Proteins
 
 
© 2008 ALEXIS Corporation, Privacy Policy, Disclaimer, Feedbackheader picture © micronaut.ch, another CS2 website

Catalogs / Brochures

E-Newsletter

 

Shopping Cart [0]

 

Distributors

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.