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Interleukin Receptors
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ALX-522-057 Revised 01-Oct-08
IL-1 Receptor Type I (human):Fc (human) (recombinant)
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SYNONYMS IL-1RI (human):Fc (human) (recombinant)
Interleukin-1 Receptor Type I (human):Fc (human) (recombinant)
CD121a (human):Fc (human) (recombinant)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Interleukin Receptors
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ALX-522-057-C050   50 µg 365.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
MW: ~83kDa (SDS-PAGE).
SOURCE/HOST: Produced in HEK 293 cells. Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused to the Fc portion of human IgG1.
CONCENTRATION: 1mg/ml after reconstitution.
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Lyophilized. Contains PBS.
ENDOTOXIN CONTENT: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION: Reconstitute with 50µl sterile water.
SPECIFICITY: Binds to human IL-1 (interleukin-1).
BIOLOGICAL ACTIVITY: Blocks IL-1 activity.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months after receipt when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
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General Information
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
Cytokine receptors and signal transduction: A. Miyajima, et al.; Annu. Rev. Immunol. 10, 295 (1992) Abstract
cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily: J.E. Sims, et al.; Science 241, 585 (1988) Abstract
The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense: L.A. O'Neill; Sci. STKE 2000, RE1 (2000) Abstract
IL-1 and IL-18 receptors, and their extended family: J.E. Sims, et al.; Curr. Opin. Immunol. 14, 117 (2002) Abstract
Related Products
Further Categories Containing This Product:
CD Proteins • Recombinant Proteins / Fusion Proteins • Interleukin-1 [IL-1] & Receptors / Related Products
 
 
ALX-159-001 Revised 01-Mar-06
IL-2 Receptor Fragment (human)
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SYNONYMS Interleukin-2 Receptor Fragment (human)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Interleukin Receptors
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ALX-159-001-M001   1 mg 80.00 USD Add To Cart
Product Specification
SEQUENCE: H-Gln-Arg-Arg-Gln-Arg-Lys-Ser-Arg-Arg-Thr-Ile-OH
FORMULA: C59H113N29O16
MW: 1484.7
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Substrate for protein kinase C (PKC). The peptide is derived from the cytoplasmic C-terminus of the human interleukin-2 receptor.
Product Specific Literature References
Phosphorylation of the human interleukin-2 receptor and a synthetic peptide identical to its C-terminal, cytoplasmic domain: B. Gallis, et al.; J. Biol. Chem. 261, 5075 (1986) Abstract; Full Text
Further Categories Containing This Product:
PKC Substrates • CD25 [IL-2Ralpha] / Related Products • Peptides
 
 
ALX-804-729 Revised 07-Oct-08
Monoclonal Antibody to ST2 (human) (ST33868)
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SYNONYMS anti-IL-1 Receptor-like 1 (human) MAb (ST33868)
anti-Interleukin-1 Receptor-like 1 (human) MAb (ST33868)
anti-IL1RL1 (human) MAb (ST33868)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Interleukin Receptors
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ALX-804-729-C050   50 µg 195.00 USD Add To Cart
ALX-804-729-C100   100 µg 270.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: ST33868
ISOTYPE: Mouse IgG1κ
CONCENTRATION: 1mg/ml
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant human ST2.
SPECIFICITY: Recognizes human ST2.
APPLICATION: ELISA (direct and indirect: 1:2’000-1:5’000)
Western Blot (1:2’000-1:5’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for 1-2 weeks when stored at +4°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Interleukin-33 [IL-33] & Receptors / Related Products • Monoclonal Antibodies
 
 
ALX-210-461 Revised 07-Oct-08
Polyclonal Antibody to ST2 (human)
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SYNONYMS anti-IL-1 Receptor-like 1 (human) PAb
anti-Interleukin-1 Receptor-like 1 (human) PAb
anti-IL1RL1 (human) PAb
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Interleukin Receptors
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ALX-210-461-C100   100 µg 310.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml.
PURITY DETAIL: Purified IgG.
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant human ST2.
SPECIFICITY: Recognizes human ST2.
APPLICATION: ELISA (direct and indirect: 1:2’000-1:5’000)
Western Blot (1:2’000-1:5’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for 1-2 weeks when stored at +4°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Interleukin-33 [IL-33] & Receptors / Related Products • Polyclonal Antibodies
 
 
ALX-201-370 Revised 07-Oct-08
ST2 (human) (recombinant)
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SYNONYMS IL-1 Receptor-like 1 (human) (recombinant)
Interleukin-1 Receptor-like 1 (human) (recombinant)
IL1RL1 (human) (recombinant)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Interleukin Receptors
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ALX-201-370-C050   50 µg 795.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. The signal peptide and the sequence of isoform 2 of human ST2 (IL1RL1) (aa 1-328) are fused at the C-terminus to a FLAG®-tag.
CONCENTRATION: 0.5mg/ml
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS, pH 7.2.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles.
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General Information
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link Q01638: Interleukin-1 receptor-like 1 (human) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins • Interleukin-33 [IL-33] & Receptors / Related Products
 
 
ALX-201-367 Revised 07-Oct-08
ST2 (human):Fc (human) (recombinant)
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SYNONYMS IL-1 Receptor-like 1 (human):Fc (human) (recombinant)
Interleukin-1 Receptor-like 1 (human):Fc (human) (recombinant)
IL1RL1 (human):Fc (human) (recombinant)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Interleukin Receptors
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ALX-201-367-C050   50 µg 410.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. The signal peptide and the sequence of isoform 2 of human ST2 (IL1RL1) (aa 1-328) are fused at the C-terminus to the Fc portion of human IgG1.
CONCENTRATION: 0.25mg/ml
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS, pH 7.2.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
BIOLOGICAL ACTIVITY: Interacts with human IL-33 as confirmed by pull-down assay (see figure 2).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q01638: Interleukin-1 receptor-like 1 (human) [Precursor]
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins • Interleukin-33 [IL-33] & Receptors / Related Products
 
 
ALX-522-107 Revised 07-Oct-08
ST2 (mouse):Fc (human) (recombinant)
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SYNONYMS IL-1 Receptor-like 1 (mouse):Fc (human) (recombinant)
Interleukin-1 Receptor-like 1 (mouse):Fc (human) (recombinant)
IL1RL1 (mouse):Fc (human) (recombinant)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Interleukin Receptors
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ALX-522-107-C050   50 µg 350.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST: Produced in CHO cells. Mouse ST2 (aa 27-332) is fused to the Fc portion of human IgG1.
CONCENTRATION: 1mg/ml after reconstitution.
PURITY: ≥95% (SDS-PAGE)
FORMULATION: Lyophilized. Contains PBS.
ENDOTOXIN CONTENT: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION: Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
SPECIFICITY: Binds to mouse and human IL-33.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months after receipt when stored at -20°C.
HANDLING: After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
General Information
ST2 is a transmembrane receptor of the new IL-1 family member IL-33. It induces the NF-κB pathway upon its activation and is involved in T helper type 2 response driving the production of Th2-associated cytokines. ST2 is predominantly expressed in hematopoietic tissues, and in macrophage, erythroid, epithelial and fibroblast cell lines.
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link P14719: Interleukin-1 Receptor-like 1 (mouse)
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines: J. Schmitz, et al.; Immunity 23, 479 (2005) Abstract
Related Products
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins • Interleukin-33 [IL-33] & Receptors / Related Products
 
 
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