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PI(3)K-Akt-mTOR Pathway
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ALX-307-076 Revised 12-Jun-06
D-myo-Inositol 1,2,3,5,6-pentakisphosphate . decasodium salt
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SYNONYMS Ins(1,2,3,5,6)P5 . 10Na
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-076-C100   100 µg 110.00 USD Add To Cart
ALX-307-076-M001   1 mg 540.00 USD Add To Cart
Product Specification
FORMULA: C6H7O21P5 . 10Na
MW: 570.0 . 229.9
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

General Information
MANUFACTURER Manufactured by SiChem, Germany
 
 
ALX-307-077 Revised 12-Jun-06
D-myo-Inositol 2,3,4,5,6-pentakisphosphate . decasodium salt
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SYNONYMS Ins(2,3,4,5,6)P5 . 10Na
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-077-C100   100 µg 110.00 USD Add To Cart
ALX-307-077-M001   1 mg 540.00 USD Add To Cart
Product Specification
FORMULA: C6H7O21P5 . 10Na
MW: 570.0 . 229.9
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

General Information
MANUFACTURER Manufactured by SiChem, Germany
 
 
ALX-307-042 Revised 23-Jun-05
D-myo-Inositol 1,2,3-trisphosphate . tripotassium salt
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SYNONYMS Ins(1,2,3)P3 . 3K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-042-C100   100 µg 150.00 USD Add To Cart
Product Specification
FORMULA: C6H12O15P3 . 3K
MW: 417.1 . 117.3
PURITY: ≥99%
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.

Product Description
Constituent of mammalian cells. Shows antioxidant properties.
Product Specific Literature References
Inositol 1,2,3-trisphosphate and inositol 1,2- and/or 2,3-bisphosphate are normal constituents of mammalian cells: C.J. Barker, et al.; Biochem. J. 306, 557 (1995) Abstract
Antioxidant functions of inositol 1,2,3-trisphosphate and inositol 1,2,3,6-tetrakisphosphate: B.Q. Phillipy & E. Graf; Free Radic. Biol. Med. 22, 939 (1997) Abstract
Enzyme-assisted total synthesis of the optical antipodes D-myo-inositol 3,4,5-trisphosphate and D-myo-ins 1,5, 6-P3: aspects of their structure-activity relationship to biologically active ins P: S. Adelt, et al.; J. Med. Chem. 42, 1262 (1999) Abstract
 
 
ALX-307-006 Revised 23-Jun-05
D-myo-Inositol 1,3,4-trisphosphate . hexapotassium salt
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SYNONYMS Ins(1,3,4)P3 . 6K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-006-C100   100 µg 160.00 USD Add To Cart
ALX-307-006-M001   1 mg 760.00 USD Add To Cart
Product Specification
FORMULA: C6H9O15P3 . 6K
MW: 414.1 . 234.6
CAS NUMBER: 140385-74-6
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

Product Description
Produced upon hormonal stimulation of cells. Precursor is postulated to be Ins(1,3,4,5)P4 (Prod. No. ALX-307-005). For the enantiomer Ins(1,3,6)P3, see Prod. No. ALX-307-050. For the cell permeable AM-derivative, see Prod. No. ALX-307-045.
Product Specific Literature References
Interconversion of inositol (1,4,5)-trisphosphate to inositol (1,3,4,5)- tetrakisphosphate and (1,3,4)-trisphosphate in permeabilized adrenal glomerulosa cells is calcium-sensitive and ATP-dependent: M.F. Rossier, et al.; BBRC 139, 259 (1986) Abstract
The metabolism of inositol 1,3,4-trisphosphate to inositol 1,3-bisphosphate: V.S. Bansal, et al.; J. Biol. Chem. 262, 9444 (1987) Abstract; Full Text
Pathway for inositol 1,3,4-trisphosphate and 1,4-bisphosphate metabolism: R.C. Inhorn, et al.; PNAS 84, 2170 (1987) Abstract
Calcium modulates the generation of inositol 1,3,4-trisphosphate in human platelets by the activation of inositol 1,4,5-trisphosphate 3-kinase: J.L. Daniel, et al.; Biochem. J. 253, 789 (1988) Abstract
Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate: X. Yang, et al.; J. Biol. Chem. 274, 18973 (1999) Abstract; Full Text
General Information
MANUFACTURER Manufactured by SiChem, Germany
 
 
ALX-307-047 Revised 17-Aug-06
D-myo-Inositol 1,3,5-trisphosphate . hexasodium salt
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SYNONYMS Ins(1,3,5)P3 . 6Na
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-047-C100   100 µg 160.00 USD Add To Cart
ALX-307-047-M001   1 mg 760.00 USD Add To Cart
Product Specification
FORMULA: C6H9O15P3 . 6Na
MW: 414.1 . 137.9
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

General Information
MANUFACTURER Manufactured by SiChem, Germany
 
 
ALX-307-050 Revised 17-Aug-06
D-myo-Inositol 1,3,6-trisphosphate . hexasodium salt
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SYNONYMS Ins(1,3,6)P3 . 6Na
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-050-C100   100 µg 160.00 USD Add To Cart
ALX-307-050-M001   1 mg 760.00 USD Add To Cart
Product Specification
FORMULA: C6H9O15P3 . 6Na
MW: 414.1 . 137.9
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

Product Description
Enantiomer of Ins(1,3,4)P3 (Prod. No. ALX-307-006). Control compound.
Product Specific Literature References
Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate: X. Yang, et al.; J. Biol. Chem. 274, 18973 (1999) Abstract; Full Text
General Information
MANUFACTURER Manufactured by SiChem, Germany.
 
 
ALX-307-007 Revised 27-Jun-05
D-myo-Inositol 1,4,5-trisphosphate . hexapotassium salt
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SYNONYMS Ins(1,4,5)P3 . 6K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-007-M001   1 mg 70.00 USD Add To Cart
ALX-307-007-M005   5 mg 280.00 USD Add To Cart
Product Specification
FORMULA: C6H9O15P3 . 6K
MW: 414.1 . 234.6
CAS NUMBER: 103476-24-0
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

Product Description
Product of phosphatidylinositol phospholipid hydrolysis. Causes release of calcium from intracellular stores.
Product Specific Literature References
myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver: S.K. Joseph, et al.; J. Biol. Chem. 259, 3077 (1984) Abstract
Inositol trisphosphate and diacylglycerol: two interacting second messengers: M.J. Berridge, et al.; Annu. Rev. Biochem. 56, 159 (1987) Abstract
Inositol 1,4,5-trisphosphate-activated calcium channels: C.D. Ferris & S.H. Snyder; Annu. Rev. Physiol. 54, 469 (1992) Abstract
General Information
MANUFACTURER Manufactured by SiChem, Germany.
 
 
ALX-307-009 Revised 27-Jun-05
D-myo-Inositol 1,4,5-trisphosphate . hexasodium salt
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SYNONYMS Ins(1,4,5)P3 . 6Na
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-009-M001   1 mg 90.00 USD Add To Cart
ALX-307-009-M005   5 mg 360.00 USD Add To Cart
Product Specification
FORMULA: C6H9O15P3 . 6Na
MW: 414.1 . 137.9
CAS NUMBER: 108340-81-4
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

Product Description
Product of phosphatidylinositol phospholipid hydrolysis. Causes release of calcium from intracellular stores.
General Information
MANUFACTURER Manufactured by SiChem, Germany.
 
 
ALX-307-011 Revised 27-Jun-05
D-myo-Inositol 1,4,5-trisphosphate . triammonium salt
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SYNONYMS Ins(1,4,5)P3 . 3NH4
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-011-M001   1 mg 90.00 USD Add To Cart
ALX-307-011-M005   5 mg 360.00 USD Add To Cart
Product Specification
FORMULA: C6H12O15P3 . 3NH4
MW: 417.1 . 54.1
CAS NUMBER: 112571-69-4
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

Product Description
Product of phosphatidylinositol phospholipid hydrolysis. Causes release of calcium from intracellular stores.
General Information
MANUFACTURER Manufactured by SiChem, Germany.
 
 
ALX-307-013 Revised 27-Jun-05
D-myo-Inositol 1,4,5-trisphosphate . trilithium salt
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SYNONYMS Ins(1,4,5)P3 . 3Li
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-013-M001   1 mg 90.00 USD Add To Cart
ALX-307-013-M005   5 mg 360.00 USD Add To Cart
Product Specification
FORMULA: C6H12O15P3 . 3Li
MW: 417.1 . 20.8
CAS NUMBER: 129828-69-91
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

Product Description
Product of phosphatidylinositol phospholipid hydrolysis. Causes release of calcium from intracellular stores.
Product Specific Literature References
myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver: S.K. Joseph, et al.; J. Biol. Chem. 259, 3077 (1984) Abstract; Full Text
Inositol trisphosphate and diacylglycerol: two interacting second messengers: M.J. Berridge; Ann. Rev. Biochem. 56, 159 (1987) Abstract
Inositol 1,4,5-trisphosphate-activated calcium channels: C.D. Ferris & S.H. Snyder; Annu. Rev. Physiol. 54, 469 (1992) Abstract
General Information
MANUFACTURER Manufactured by SiChem, Germany.
 
 
ALX-307-070 Revised 23-Sep-05
D-myo-Inositol 1,4,5-trisphosphate (caged) . trisodium salt
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SYNONYMS Ins(1,4,5)P3 (caged) . 3Na
D-myo-Inositol 1,4,5-trisphosphate, P4-1-(2-nitrophenyl)ethyl ester . 3Na
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
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ALX-307-070-C010   10 µg