• Home
  • Sitemap
  • Help
  • Technical Support
  • Contact
PI(3)K-Akt-mTOR Pathway
You are here: Product Lines > Signal Transduction > PI(3)K-Akt-mTOR Pathway
 
Toolbar - View Selection
 
 Items 60-80 of 110 Page 4 of 6 Select Page: << 1 2 3 4 5 6  >>  
ALX-804-400 Revised 20-Sep-07
Monoclonal Antibody to Akt (dephosphorylated) (11A11)
Add to Clipboard
SYNONYMS anti-PKB (dephosphorylated) MAb (11A11)
anti-Protein Kinase B (dephosphorylated) MAb (11A11)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Akt [PKB] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-400-C100   100 µg 380.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Dog
CLONE: 11A11
ISOTYPE: Mouse IgG1
PURITY DETAIL: Purified from serum-free cell culture supernatant by subsequent thiophilic adsorption and size exclusion chromatography.
FORMULATION: Lyophilized from 1ml 2x PBS containing 0.09% sodium azide, PEG and sucrose.
RECONSTITUTION: Reconstitute with 1ml distilled water (15 min., RT).
IMMUNOGEN: Synthetic peptide corresponding to C-terminal (QFSYSA) of human Akt (protein Kinase B; PKB) dephosphorylated at Ser472/473/474.
SPECIFICITY: Recognizes human, mouse, rat and dog Ser472/473/474-dephosphorylated Akt (see technical note). Does not cross-react with Ser472/473/474-phosphorylated Akt.
APPLICATION: Immunohistochemistry
Western Blot (0.5µg/ml for HRPO/ECL detection).
Recommended blocking buffer CPPT: 10mM TRIS-HCl, pH 7.4, 0.5% (w/v) casein, 1% (w/v) PEG 4’000, 1% (w/v) polyvinylpyrrolidone, 0.1% (v/v) Tween 20, 150mM sodium chloride.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Reconstituted antibody is stable for 1 year when stored at -80°C. Thaw aliquots at +37°C. Thawed aliquots may be stored at +4°C for up to 3 months.
HANDLING: Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and freeze in liquid nitrogen.
POSITIVE CONTROL:

Included (Prod. No. ALX-840-030).
General Information
BACKGROUND/TECHNICAL INFORMATION Technical Note: There are three mammalian isoforms of Akt: Akt1 (PKBα), Akt2 (PKBβ), and Akt3 (PKBγ). Akt1 shares 81% and 83% aa identity with Akt2 and Akt3, respectively. Although the three isoforms show broad tissue distribution, Akt1 is most ubiquitously expressed. Akt2 is expressed at a lower level than Akt1 except in insulin-responsive tissues where it predominates. Akt2 is more abundant and more highly activated than Akt1 in adipocytes. Akt3 is expressed at the lowest level except in testes and brain. The C-terminal sequence of the three isoforms are shown below. The phosphorylation site slightly differs, thus the phosphorylation site Ser473 of Akt1 corresponds to Ser474 in Akt2 and Ser472 in Akt3.

Akt1:  V461DSERRPHFPQFS473YSASSTA480       Swiss-Prot-Link: P31749
Akt2:  L461LELDQRTHFPQFS474YSASIRE481        Swiss-Prot-Link: P31751
Akt3:  D461NERRPHFPQFS472YSASGRE479         Swiss-Prot-Link: Q9Y243
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-553 Revised 01-Dec-05
Monoclonal Antibody to Akt (5C10)
Add to Clipboard
SYNONYMS anti-PKB MAb (5C10)
anti-Protein Kinase B MAb (5C10)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Akt [PKB] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-553-C100   100 µg 380.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Dog
CLONE: 5C10
ISOTYPE: Mouse IgG1
PURITY DETAIL: Purified from serum-free cell culture supernatant by subsequent thiophilic adsorption and size exclusion chromatography.
FORMULATION: Lyophilized from 1ml 2x PBS, 0.1% sodium azide, PEG and sucrose.
RECONSTITUTION: Reconstitute with 1ml distilled water (15min, RT).
IMMUNOGEN: Synthetic peptide corresponding to C-terminal human Akt (protein kinase B; PKB).
SPECIFICITY: Recognizes a c-terminal epitope (aa 466-480) of phosphorylated and non-phosphorylated human, mouse, rat and dog Akt isoforms (see Technical Note below).
APPLICATION: Western Blot (0.5µg/ml for HRPO/ECL detection).
Recommended blocking buffer CPPT: 10mM TRIS-HCl, pH 7.4, 0.5% (w/v) casein, 1% (w/v) PEG 4'000, 1% (w/v) polyvinylpyrrolidone, 0.1% (v/v) Tween 20, 150mM sodium chloride.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Reconstituted antibody is stable for 1 year when stored at -80°C. Thaw aliquots at +37°C. Thawed aliquots may be stored at +4°C for up to 3 months.
HANDLING: Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and freeze in liquid nitrogen.
POSITIVE CONTROL INCLUDED: Yes (Prod. No. ALX-840-030).
General Information
BACKGROUND/TECHNICAL INFORMATION Technical Note: There are three mammalian isoforms of Akt: Akt1 (PKBa), Akt2 (PKBb), and Akt3 (PKBg). Akt1 shares 81% and 83% amino acid identity with Akt2 and Akt3, respectively. Although the three isoforms show broad tissue distribution, Akt1 is the most ubiquitously expressed. Akt2 is expressed at a lower level than Akt1 except in insulin-responsive tissues where it predominates. In particular, Akt2 is more abundant and more highly activated than Akt1 in adipocytes. Akt3 is expressed at the lowest level except in testes and brain. The C-terminal sequence of the three isoforms are shown below. Note that the phosphorylation site slightly differs between the three isoforms.Thus the phosphorylation site Ser473 of Akt1 corresponds to Ser474 in Akt2 and Ser472 in Akt3 respectively.

Akt1:  V461DSERRPHFPQFS473YSASSTA480       Swiss-Prot-Link: P31749
Akt2: L461LELDQRTHFPQFS474YSASIRE481         Swiss-Prot-Link: P31751
Akt3:     D461NERRPHFPQFS472YSASGRE479      Swiss-Prot-Link: Q9Y243
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-803-303 Revised 18-Sep-07
Monoclonal Antibody to Akt (19G7)
Add to Clipboard
SYNONYMS anti-PKB MAb (19G7)
anti-Protein Kinase B MAb (19G7)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Akt [PKB] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-803-303-C100   100 µg 240.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Dog
CLONE: 19G7
ISOTYPE: Mouse IgG1
CONCENTRATION: 0.2mg/ml
PURITY: Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
PURITY DETAIL: Protein A-affinity purified.
IMMUNOGEN: Recombinant mouse Akt (protein kinase B; PKB).
SPECIFICITY: Recognizes human, mouse, rat, dog and hamster Akt. Detects Akt1 (PKB-α) and Akt2 (PKB-β) strong than Akt3 (PKB-γ). Detects also phosphorylated forms of Akt.
APPLICATION: ELISA
Immunoprecipitation (5µg per 700µl protein extract)
Western Blot
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
Further Categories Containing This Product:
Phospho-specific Antibodies • Monoclonal Antibodies
 
 
ALX-804-634 Revised 05-Jun-07
Monoclonal Antibody to Akt2 (human) (8B7)
Add to Clipboard
SYNONYMS anti-PKBβ MAb (human) (8B7)
anti-Protein Kinase Bβ MAb (human) (8B7)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Akt [PKB] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-634-C100   100 µg 453.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 8B7
ISOTYPE: Mouse IgG2a
PURITY DETAIL: Purified from serum-free cell culture supernatant by subsequent thiophilic adsorption and size exclusion chromatography.
FORMULATION: Lyophilized from 1ml 2x PBS, 0.09% sodium azide, PEG and sucrose.
RECONSTITUTION: Reconstitute with 1ml distilled water (15 min., RT).
IMMUNOGEN: Synthetic peptide corresponding to human Akt2 (Protein Kinase Bβ; PKBβ).
SPECIFICITY: Recognizes human Akt2 (see Technical Note below).
APPLICATION: Immunohistochemistry
Western Blot (0.5µg/ml for HRPO/ECL detection). Recommended blocking buffer CPPT: 10mM TRIS-HCl, pH 7.4, 0.5% (w/v) casein, 1% (w/v) PEG 4’000, 1% (w/v) polyvinylpyrrolidone, 0.1% (v/v) Tween 20, 150mM sodium chloride.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Reconstituted antibody is stable for 1 year when stored at -80°C. Thaw aliquots at +37°C. Thawed aliquots may be stored at +4°C for up to 3 months.
HANDLING: Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and freeze in liquid nitrogen.
POSITIVE CONTROL: Included (Prod. No. ALX-840-030).
General Information
BACKGROUND/TECHNICAL INFORMATION Technical Note: There are three mammalian isoforms of Akt: Akt1 (PKBα), Akt2 (PKBβ), and Akt3 (PKBγ). Akt1 shares 81% and 83% amino acid identity with Akt2 and Akt3, respectively. Although the three isoforms show broad tissue distribution, Akt1 is the most ubiquitously expressed. Akt2 is expressed at a lower level than Akt1 except in insulin-responsive tissues where it predominates. In particular, Akt2 is more abundant and more highly activated than Akt1 in adipocytes. Akt3 is expressed at the lowest level except in testes and brain. The C-terminal sequence of the three isoforms are shown below. Note that the phosphorylation site slightly differs between the three isoforms.Thus the phosphorylation site Ser473 of Akt1 corresponds to Ser474 in Akt2 and Ser472 in Akt3 respectively.

Akt1:  V461DSERRPHFPQFS473YSASSTA480       Swiss-Prot-Link: P31749
Akt2:  L461LELDQRTHFPQFS474YSASIRE481        Swiss-Prot-Link: P31751
Akt3:  D461NERRPHFPQFS472YSASGRE479         Swiss-Prot-Link: Q9Y243
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-401 Revised 28-Mar-08
Monoclonal Antibody to Akt (phosphorylated) (pSer473) (11E6)
Add to Clipboard
SYNONYMS anti-PKB (phosphorylated) (pSer473) MAb (11E6)
anti-Protein Kinase B (phosphorylated) (pSer473) MAb (11E6)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Akt [PKB] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-401-C100   100 µg 453.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Dog
CLONE: 11E6
ISOTYPE: Mouse IgG1
PURITY DETAIL: Purified from serum-free cell culture supernatant by subsequent thiophilic adsorption and size exclusion chromatography.
FORMULATION: Lyophilized from 1ml 2x PBS containing 0.09% sodium azide, PEG and sucrose.
RECONSTITUTION: Reconstitute with 1ml distilled water (15 min., RT).
IMMUNOGEN: Synthetic peptide corresponding to C-terminal (PQFpSYSA) of human Akt (protein kinase B; PKB) phosphorylated at Ser473.
SPECIFICITY: Recognizes human, mouse, rat and dog Ser472/473/474-phosphorylated Akt (see technical note). Does not cross-react with dephosphorylated Akt or other unrelated serine-phosphorylated proteins.
APPLICATION: Flow Cytometry
Immunohistochemistry
Western Blot: (0.5µg/ml for HRPO/ECL detection).
Recommended blocking buffer CPPT: 10mM TRIS-HCl, pH 7.4, 0.5% (w/v) casein, 1% (w/v) PEG 4’000, 1% (w/v) polyvinylpyrrolidone, 0.1% (v/v) Tween 20, 150mM sodium chloride.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY:

Reconstituted antibody is stable for 1 year when stored at -80°C. Thaw aliquots at +37°C. Thawed aliquots may be stored at +4°C for up to 3 months.
HANDLING: After reconstitution, prepare aliquots and freeze in liquid nitrogen. Avoid freeze/thaw cycles.
POSITIVE CONTROL: Included (Prod. No. ALX-840-027).
General Information
BACKGROUND/TECHNICAL INFORMATION Technical Note: There are three mammalian isoforms of Akt: Akt1 (PKBα), Akt2 (PKBβ), and Akt3 (PKBγ). Akt1 shares 81% and 83% aa identity with Akt2 and Akt3, respectively. Although the three isoforms show broad tissue distribution, Akt1 is most ubiquitously expressed. Akt2 is expressed at a lower level than Akt1 except in insulin-responsive tissues where it predominates. Akt2 is more abundant and more highly activated than Akt1 in adipocytes. Akt3 is expressed at the lowest level except in testes and brain. The C-terminal sequence of the three isoforms are shown below. The phosphorylation site slightly differs, thus the phosphorylation site Ser473 of Akt1 corresponds to Ser474 in Akt2 and Ser472 in Akt3.

Akt1:  V461DSERRPHFPQFS473YSASSTA480       Swiss-Prot-Link: P31749
Akt2:  L461LELDQRTHFPQFS474YSASIRE481       Swiss-Prot-Link: P31751
Akt3:  D461NERRPHFPQFS472YSASGRE479        Swiss-Prot-Link: Q9Y243
Further Categories Containing This Product:
Phospho-specific Antibodies • Monoclonal Antibodies
 
 
ALX-804-633 Revised 05-Jun-07
Monoclonal Antibody to Akt1 (5G12)
Add to Clipboard
SYNONYMS anti-PKBα MAb (5G12)
anti-Protein Kinase Bα MAb (5G12)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Akt [PKB] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-633-C100   100 µg 453.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Rat
Dog
CLONE: 5G12
ISOTYPE: Mouse IgG1
CONCENTRATION: 0.1mg/ml
PURITY DETAIL: Purified from serum-free cell culture supernatant by subsequent thiophilic adsorption and size exclusion chromatography.
FORMULATION: Liquid. In PBS containing 50% glycerol, 0.09% sodium azide, PEG and sucrose.
IMMUNOGEN: Synthetic peptide corresponding to human Akt1 (Protein Kinase Bα; PKBα).
SPECIFICITY: Recognizes human, rat and dog Akt1 (see Technical Note below).
APPLICATION: Immunohistochemistry
Western Blot (0.5µg/ml for HRPO/ECL detection). Recommended blocking buffer CPPT: 10mM TRIS-HCl, pH 7.4, 0.5% (w/v) casein, 1% (w/v) PEG 4’000, 1% (w/v) polyvinylpyrrolidone, 0.1% (v/v) Tween 20, 150mM sodium chloride.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Reconstituted antibody is stable for 1 year when stored at -80°C. Thaw aliquots at +37°C. Thawed aliquots may be stored at +4°C for up to 3 months.
HANDLING: After reconstitution, prepare aliquots and freeze in liquid nitrogen. Avoid freeze/thaw cycles.
POSITIVE CONTROL: Included (Prod. No. ALX-840-038).
General Information
BACKGROUND/TECHNICAL INFORMATION Technical Note: There are three mammalian isoforms of Akt: Akt1 (PKBα), Akt2 (PKBβ), and Akt3 (PKBγ). Akt1 shares 81% and 83% amino acid identity with Akt2 and Akt3, respectively. Although the three isoforms show broad tissue distribution, Akt1 is the most ubiquitously expressed. Akt2 is expressed at a lower level than Akt1 except in insulin-responsive tissues where it predominates. In particular, Akt2 is more abundant and more highly activated than Akt1 in adipocytes. Akt3 is expressed at the lowest level except in testes and brain. The C-terminal sequence of the three isoforms are shown below. Note that the phosphorylation site slightly differs between the three isoforms.Thus the phosphorylation site Ser473 of Akt1 corresponds to Ser474 in Akt2 and Ser472 in Akt3 respectively.

Akt1:  V461DSERRPHFPQFS473YSASSTA480       Swiss-Prot-Link: P31749
Akt2:  L461LELDQRTHFPQFS474YSASIRE481        Swiss-Prot-Link: P31751
Akt3:  D461NERRPHFPQFS472YSASGRE479         Swiss-Prot-Link: Q9Y243
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-379 Revised 20-Sep-05
Monoclonal Antibody to Akt3 (human) (66C1247.1)
Add to Clipboard
SYNONYMS anti-PKBγ (human) MAb (66C1247.1)
anti-Protein Kinase Bγ (human) MAb (66C1247.1)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Akt [PKB] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-379-C100   100 µg 293.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 66C1247.1
ISOTYPE: Mouse IgG1
CONCENTRATION: 0.5mg/ml
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide and 0.1mg/ml BSA.
IMMUNOGEN: Synthetic peptide corresponding to aa 119-136 of human Akt3 (protein kinase Bγ; PKBγ). This sequence is completely conserved in mouse and rat Akt3.
SPECIFICITY: Recognizes human Akt3. Detects a band of ~50kDa by Western blot.
APPLICATION: Western Blot (1-2µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for 6 months when stored at +4°C.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-852 Revised 28-Apr-08
Monoclonal Antibody to Omentin 1 (Saly-2)
Add to Clipboard
SYNONYMS anti-Intelectin-1 MAb (Saly-2)
anti-Intestinal Lactoferrin Receptor MAb (Saly-2)
anti-Galactofuranose-binding Lectin MAb (Saly-2)
anti-Endothelial Lectin HL-1 MAb (Saly-2)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Omentin / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-852-C100   100 µg 360.00 USD Add To Cart
ALX-804-852B-C100 Biotin 100 µg 390.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Rat
CLONE: Saly-2
ISOTYPE: Mouse IgG2a
SOURCE/HOST: Purified from concentrated hybridoma tissue cell culture supernatant.
CONCENTRATION: 1mg/ml
PURITY: ≥95% (SDS-PAGE)
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant human omentin 1 (intelectin-1) (aa 17-231).
SPECIFICITY: Recognizes human omentin 1 and rat omentin. Cross-reacts with human omentin 2.
APPLICATION: ELISA (detection)
Western Blot (1:1'000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
USE/STABILITY: Stable for at least 1 year after receipt when stored at -20°C.
HANDLING: For long term storage keep unconjugated antibody at -20°C. Avoid freeze/thaw cycles. Keep conjugated formats at +4°C. Do not freeze. Protect from light.
General Information
Omentin 1 (also named intelectin-1, endothelial lectin HL-1 and intestinal lactoferrin receptor) has been recently identified as a novel visceral fat (or omental fat) depot-specific adipokine. Omentin 1 is a secreted protein of ~38 kDa containing a fibrinogen-related domain. Omentin 1 is highly expressed in the omental fat, and much less in intestine, lung and heart. Addition of recombinant omentin in vitro did not affect basal, but enhanced insulin-stimulated glucose uptake in subcutaneous as well as in omental human adipocytes. Omentin 1 triggers AKT signalling in the absence of insulin.
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action: R.Z. Yang, et al.; Am. J. Physiol. Endocrinol. Metab. 290, E1253 (2006) Abstract
Related Products
Further Categories Containing This Product:
PI(3)K-Akt-mTOR Pathway Other Products • Monoclonal Antibodies
 
 
ALX-804-850 Revised 16-Aug-07
Monoclonal Antibody to Omentin 1 (human) (Saly-1)
Add to Clipboard
SYNONYMS anti-Intelectin-1 (human) MAb (Saly-1)
anti-Intestinal Lactoferrin Receptor (human) MAb (Saly-1)
anti-Galactofuranose-binding Lectin (human) MAb (Saly-1)
anti-Endothelial Lectin HL-1 (human) MAb (Saly-1)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Omentin / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-850-C100   100 µg 360.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: Saly-1
ISOTYPE: Mouse IgG2b
SOURCE/HOST: Purified from concentrated hybridoma tissue cell culture supernatant.
CONCENTRATION: 1mg/ml
PURITY: ≥95% (SDS-PAGE)
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant human omentin 1 (intelectin-1) (aa 17-231).
SPECIFICITY: Recognizes human omentin 1.
APPLICATION: ELISA (capture)
Immunohistochemistry (paraffin sections)
Western Blot (1:1’000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year after receipt when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
Omentin 1 (also named intelectin-1, endothelial lectin HL-1 and intestinal lactoferrin receptor) has been recently identified as a novel visceral fat (or omental fat) depot-specific adipokine. Omentin 1 is a secreted protein of ~38 kDa containing a fibrinogen-related domain. Omentin 1 is highly expressed in the omental fat, and much less in intestine, lung and heart. Addition of recombinant omentin in vitro did not affect basal, but enhanced insulin-stimulated glucose uptake in subcutaneous as well as in omental human adipocytes. Omentin 1 triggers AKT signalling in the absence of insulin.
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action: R.Z. Yang, et al.; Am. J. Physiol. Endocrinol. Metab. 290, E1253 (2006) Abstract
Related Products