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ALX-201-275
Revised 18-Mar-08
Activator of HSP90 ATPase 1 (human) (recombinant)
SYNONYMS
AHA1 (human) (recombinant)
PRODUCT LINE
Stress & Heat Shock Proteins
PRODUCT CATEGORY
HSP90/HtpG/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-201-275-C100
100 µg
320.00 USD
Product Specification
MW:
~36.1kDa
SOURCE/HOST:
Produced in
E.coli
.
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE)
FORMULATION:
Liquid. In 20mM TRIS, pH 8.0, containing 2mM EDTA.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
General Information
BACKGROUND/TECHNICAL INFORMATION
Swiss-Prot link Q12449:
Activator of HSP90 ATPase-1 (human)
Further Categories Containing This Product:
Co-Chaperones & HSP-interacting Proteins/Related Products
•
Recombinant Proteins/Fusion Proteins
ALX-201-148
Revised 16-Feb-05
Cdc37 (yeast) (recombinant)
SYNONYMS
Cell Division Control Protein 37 (yeast) (recombinant)
HSP90 Co-chaperone Cdc37 (yeast) (recombinant)
HSP90 Chaperone Protein Kinase-targeting Subunit (yeast) (recombinant)
PRODUCT LINE
Stress & Heat Shock Proteins
PRODUCT CATEGORY
Co-Chaperones & HSP-interacting Proteins/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-201-148-C025
25 µg
155.00 USD
Product Specification
SOURCE/HOST:
Produced in
E. coli
.
CONCENTRATION:
1.7mg/ml
PURITY:
≥99%
FORMULATION:
Liquid. In 50mM TRIS/HCl, pH 7.5, containing 50mM NaCl, 5mM EDTA and 1mM DTT.
SHIPPING:
SHIPPED ON DRY ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-80°C
HANDLING:
For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles.
Product Specific Literature References
Regulation of Hsp90 ATPase activity by the co-chaperone Cdc37p/p50cdc37
:
G. Siligardi, et al.; J. Biol. Chem.
277
, 20151 (2002)
Abstract
;
Full Text
General Information
BACKGROUND/TECHNICAL INFORMATION
Swiss-Prot link P06101:
HSP90 Co-chaperone Cdc73 (
Saccharomyces cerevisiae
(Baker's yeast))
General Literature References
Heat-shock protein 90, a chaperone for folding and regulation
:
D. Picard; Cell. Mol. Life Sci.
59
, 1640 (2002), (Review)
Abstract
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
ALX-201-215
Revised 02-Apr-08
CHIP (human) (recombinant)
SYNONYMS
C-terminus of HSC70 Interacting Protein
PRODUCT LINE
Stress & Heat Shock Proteins
PRODUCT CATEGORY
Co-Chaperones & HSP-interacting Proteins/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-201-215-C025
25 µg
160.00 USD
Product Specification
SOURCE/HOST:
Produced in
E. coli
.
CONCENTRATION:
1mg/ml
PURITY:
≥99%
FORMULATION:
Liquid. In 50mM HEPES/KOH, pH 7.0, containing 50mM potassium chloride, 5mM DTT and 10% (v/v) glycerol.
SHIPPING:
SHIPPED ON DRY ICE
LONG TERM STORAGE:
-80°C
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
Dimerization of the human E3 ligase CHIP via a coiled-coil domain is essential for its activity
:
R. Nikolay, et al.; J. Biol. Chem.
279
, 2673 (2004)
Abstract
;
Full Text
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
•
Chaperone-mediated Autophagy [CMA]
•
Ubiquitin Ligases [E3]
ALX-201-144
Revised 08-Jun-06
DnaJ (E. coli) (recombinant)
SYNONYMS
Heat Shock Protein 40 (
E. coli
) (recombinant)
HSP40 (
E. coli
) (recombinant)
Heat Shock Protein J (
E. coli
) (recombinant)
PRODUCT LINE
Stress & Heat Shock Proteins
PRODUCT CATEGORY
Co-Chaperones & HSP-interacting Proteins/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-201-144-C025
25 µg
290.00 USD
Product Specification
SOURCE/HOST:
Produced in
E. coli
.
CONCENTRATION:
4.3mg/ml
PURITY:
≥99%
FORMULATION:
Liquid. In 30mM HEPES/KOH, pH 8.2, containing 120mM KCl, 15mM NaCl and 4% glycerol.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-80°C
HANDLING:
For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles.
Product Specific Literature References
Escherichia coli DnaJ and GrpE heat shock proteins jointly stimulate ATPase activity of DnaK
:
K. Liberek, et al.; PNAS
88
, 2874 (1991)
Abstract
;
Full Text
General Information
BACKGROUND/TECHNICAL INFORMATION
Swiss-Prot link P08622:
Chaperone protein dnaJ (
E. coli
)
General Literature References
Protein folding and degradation in bacteria: to degrade or not to degrade? That is the question
:
D.A. Dougan, et al.; Cell. Mol. Life Sci.
59
, 1607 (2002), (Review)
Abstract
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
ALX-201-142
Revised 10-Feb-05
GroES (E. coli) (recombinant)
SYNONYMS
Heat Shock Protein 10 (
E. coli
) (recombinant)
HSP10 (
E. coli
) (recombinant)
10kDa Chaperonin (
E. coli
) (recombinant)
Protein Cpn10 GroES Protein (
E. coli
) (recombinant)
PRODUCT LINE
Stress & Heat Shock Proteins
PRODUCT CATEGORY
HSP60/GroEL/Related Products
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Format:
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ALX-201-142-C025
25 µg
155.00 USD
Product Specification
SOURCE/HOST:
Produced in
E. coli
.
CONCENTRATION:
4.2mg/ml
PURITY:
≥99%
FORMULATION:
Liquid. In 50mM TRIS/HCl, pH 8.0, containing 10mM KCl and 10mM MgCl
2
.
SHIPPING:
SHIPPED ON DRY ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-80°C
HANDLING:
For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles.
Product Specific Literature References
Suppression of the Escherichia coli dnaA46 mutation by amplification of the groES and groEL genes
:
O. Fayet, et al.; Mol. Gen. Genet.
202
, 435 (1986)
Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION
Swiss-Prot link P05380:
10kDa chaperonin (
E. coli
)
General Literature References
Structure and function of the GroE chaperone
:
S. Walter; Cell. Mol. Life Sci.
59
, 1589 (2002), (Review)
Abstract
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
•
Co-Chaperones & HSP-interacting Proteins/Related Products
ALX-201-145
Revised 10-Feb-05
GrpE (E. coli) (recombinant)
SYNONYMS
HSP24 (
E. coli
) (recombinant)
HSP70 Cofactor (
E. coli
) (recombinant)
Nucleotide Exchange Factor (
E. coli
) (recombinant)
PRODUCT LINE
Stress & Heat Shock Proteins
PRODUCT CATEGORY
Co-Chaperones & HSP-interacting Proteins/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-201-145-C025
25 µg
155.00 USD
Product Specification
SOURCE/HOST:
Produced in
E. coli.
CONCENTRATION:
2.15mg/ml
PURITY:
≥99%
FORMULATION:
Liquid. In 30mM HEPES/KOH, pH 7.0, containing 10mM KCl and 5% glycerol.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-80°C
HANDLING:
For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles.
Product Specific Literature References
Structure-function analysis of the Escherichia coli GrpE heat shock protein
:
B. Wu, et al.; EMBO J.
15
, 4806 (1996)
Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION
Swiss-Prot link P09372:
GrpE protein (
E. coli
)
General Literature References
Protein folding and degradation in bacteria: to degrade or not to degrade? That is the question
:
D.A. Dougan, et al.; Cell. Mol. Life Sci.
59
, 1607 (2002), (Review)
Abstract
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
ALX-201-211
Revised 27-Jul-06
HDJ1 (human) (recombinant)
PRODUCT LINE
Stress & Heat Shock Proteins
PRODUCT CATEGORY
Co-Chaperones & HSP-interacting Proteins/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-201-211-C025
25 µg
160.00 USD
Product Specification
SOURCE/HOST:
Produced in
E. coli
.
CONCENTRATION:
1mg/ml.
PURITY:
≥95%
FORMULATION:
Liquid. In 50mM TRIS-HCl, pH 7.7, containing 100mM potassium chloride.
SHIPPING:
SHIPPED ON DRY ICE
LONG TERM STORAGE:
-80°C
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
Regulation of the heat-shock protein 70 reaction cycle by the mammalian DnaJ homolog, Hsp40
:
Y. Minami, et al.; J. Biol. Chem.
271
, 19617 (1996)
Abstract
;
Full Text
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
ALX-201-212
Revised 26-Jun-08
HDJ2 (human) (recombinant)
PRODUCT LINE
Stress & Heat Shock Proteins
PRODUCT CATEGORY
Co-Chaperones & HSP-interacting Proteins/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-201-212-C025
25 µg
160.00 USD
Product Specification
SOURCE/HOST:
Produced in
E. coli
.
CONCENTRATION:
1mg/ml
PURITY:
≥95%
FORMULATION:
Liquid. In 50mM TRIS-HCl, pH 7.7, containing 100mM potassium chloride.
SHIPPING:
SHIPPED ON DRY ICE
LONG TERM STORAGE:
-80°C
HANDLING:
Avoid freeze/thaw cycles.
General Literature References
The human DnaJ homologue dj2 facilitates mitochondrial protein import and luciferase refolding:
K. Terada, et al.; J. Cell Biol.
139
, 1089 (1997)
Abstract
;
Full Text
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
ALX-201-216
Revised 26-Aug-08
Hip (human) (recombinant)
SYNONYMS
HSC70-interacting Protein (human) (recombinant)
p48 (human) (recombinant)
PRODUCT LINE
Stress & Heat Shock Proteins
PRODUCT CATEGORY
Co-Chaperones & HSP-interacting Proteins/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-201-216-C025
25 µg
160.00 USD
Product Specification
SOURCE/HOST:
Produced in
E. coli
.
CONCENTRATION:
2mg/ml.
PURITY:
≥99%
FORMULATION:
Liquid. In 20mM MOPS/KOH, pH 7.2, containing 250mM potassium chloride, 0.5mM EDTA and 1mM β-mercaptoethanol.
SHIPPING:
SHIPPED ON DRY ICE
LONG TERM STORAGE:
-80°C
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
GrpE-like regulation of the hsc70 chaperone by the anti-apoptotic protein BAG-1
:
J. Höhfeld and S. Jentsch; EMBO J.
16
, 6209 (1997)
Abstract
;
Full Text
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
•
Chaperone-mediated Autophagy [CMA]
ALX-201-218
Revised 18-May-05
Hop (human) (recombinant)
SYNONYMS
HSC70/HSP90-organizing Protein (human) (recombinant)
STI1
Stress-induced Phosphoprotein 1
PRODUCT LINE
Stress & Heat Shock Proteins
PRODUCT CATEGORY
Co-Chaperones & HSP-interacting Proteins/Related Products
Ordering Information
Product Numbers:
Format:
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ALX-201-218-C025
25 µg
170.00 USD
Product Specification
SOURCE/HOST:
Produced in
E. coli
.
CONCENTRATION:
PURITY:
≥99%
(SDS-PAGE; MS)
FORMULATION:
Liquid. In 40mM HEPES, pH 7.5.
APPLICATION:
Western Blot
SHIPPING:
SHIPPED ON DRY ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-80°C
HANDLING:
Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.
Product Specific Literature References
Multiple domains of the co-chaperone Hop are important for Hsp70 binding
:
P.E. Carrigan, et al.; J. Biol. Chem.
279
, 16185 (2004)
Abstract
;
Full Text
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
•
Chaperone-mediated Autophagy [CMA]
ALX-201-274
Revised 18-Mar-08
HSP40 (human) (recombinant) (His)
SYNONYMS
Heat Shock Protein 40 (human) (recombinant) (His)
DJB1 (human) (recombinant) (His)
PRODUCT LINE
Stress & Heat Shock Proteins
PRODUCT CATEGORY
Co-Chaperones & HSP-interacting Proteins/Related Products
Ordering Information
Product Numbers:
Format:
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Unit Price:
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ALX-201-274-C100
100 µg
620.00 USD
Product Specification
MW:
~40.2kDa
SOURCE/HOST:
Produced in
E.coli
and fused to a His-tag.
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE)
FORMULATION:
Liquid. In 20mM TRIS, pH 8.0, containing 2mM DDT, 0.2mM PMSF and 10% glycerol.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
General Information
BACKGROUND/TECHNICAL INFORMATION
Swiss-Prot link P25685:
Heat Shock Protein 40 (human)
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
•
Chaperone-mediated Autophagy [CMA]
ALX-803-323
Revised 27-May-08
Monoclonal Antibody to BAG-3 (AC-1)
SYNONYMS
anti-Bcl-2-binding Athanogene-3 MAb (AC-1)
anti-Docking Protein CAIR-1 MAb (AC-1)
PRODUCT LINE
Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY
Bcl-2 Family Interacting Proteins/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-803-323-C100
100 µg
280.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
CLONE:
AC-1
ISOTYPE:
Mouse IgG1
SOURCE/HOST:
Purified from concentrated hybridoma tissue culture supernatant.
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE)
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 18-33 (D
18
RDPLPPGWEIKIDPQ
33
) of N-terminal human BAG-3 (Bcl-2-binding athanogene 3).
SPECIFICITY: