Advanced Search
© 2008 Alexis Corporation
You are here:
Product Lines
> Signal Transduction
Adaptor Proteins & Interaction Domains/Related Products
Calcium Signalling (Intracellular)
cAMP Pathways
cGMP Pathways
Circadian Clock/Related Products
G-Protein Coupled Receptor Signalling
Hedgehog [Hh] Signalling Pathway
Hormones & Hormone Receptors/Related Products
Ion Channels & Transporters/Related Products
JAK/STAT Signalling Pathway
Kinases/Related Products
Lipid Signalling Pathways
MAP Kinase Pathways
NF-kB Pathway
Notch Signalling Pathway
Nucleotides, Nucleosides & Nucleobases/Related Products
Phosphatases/Related Products
PI(3)K-Akt-mTOR Pathway
Protein Kinase C [PKC]/Related Products
Ras Signalling Pathway
Receptors
Signal Transduction Enzymes/Related Products
Vision Research
Wnt Signalling Pathway/Related Products
Signal Transduction Other Products
Toolbar - View Selection
Current View:
Price List
Brief
Detail
Search Results
Current Sort:
Sort by Product Name
Sort by Product ID
Sort by Result Relevance
Sort by Class
Show:
20 Products
50 Products
100 Products
All Products
Show Selected Products Only
Show
Products Only
Items
180-200
of 2908
Page 10
of 146
Select Page:
<<
6
7
8
9
10
11
12
13
14
15
>>
ALX-850-049
Revised 17-Apr-08
Annexin V (human) ELISA Kit
PRODUCT LINE
Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY
Annexin V/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-850-049-KI01
1 Kit
619.00 USD
Product Specification
SENSITIVITY:
0.33ng/ml (range 0.8 to 50ng/ml)
QUANTITY:
96wells (~80tests).
APPLICATION:
For the quantitative detemination of human annexin V in cell culture supernatant and serum.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
General Information
MANUFACTURER
Manufactured by Bender MedSystems.
Further Categories Containing This Product:
ELISA & EIA Kits
ALX-850-040
Revised 17-Apr-08
anti-Annexin V (human) ELISA Kit
PRODUCT LINE
Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY
Annexin V/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-850-040-KI01
1 Kit
619.00 USD
Product Specification
SENSITIVITY:
1.18ng/ml (range 6.25 to 400ng/ml)
QUANTITY:
96 wells (~80 tests).
APPLICATION:
For the quantitative determination of human autoantibodies to annexin V (Vac-α) in cell culture supernatants, serum and other body fluids.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
Product Specific Literature References
Lupus anticoagulant autoantibody induces apoptosis in umbilical vein endothelial cells: involvement of annexin V:
N. Nakamura, et al.; BBRC
205
, 1488 (1994)
Abstract
Thrombosis in patients with SLE and antiphospholipid syndrome:
J. Kaburaki, et al.; Rinsho Ketsueki
36
, 320 (1995), (Article in Japanese)
Abstract
Annexin V autoantibodies in rheumatoid arthritis:
M.I. Rodriguez-Garcia, et al.; Ann. Rheum. Dis.
55
, 895 (1996)
Abstract
Clinical significance of anti-annexin V antibodies in patients with systemic lupus erythematosus:
J. Kaburaki, et al.; Am. J. Hematol.
54
, 209 (1997)
Abstract
General Information
MANUFACTURER
Manufactured by Bender MedSystems.
Further Categories Containing This Product:
ELISA & EIA Kits
ALX-430-063
Revised 10-Oct-07
Anthralin
SYNONYMS
Dithranol
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
Leukotrienes Other Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-430-063-G001
1 g
25.00 USD
Product Specification
FORMULA:
C
14
H
10
O
3
MW:
226.2
CAS NUMBER:
1143-38-0
MERCK INDEX:
14:
684
RTECS:
CB8927000
PURITY:
≥97% (HPLC)
APPEARANCE:
Yellow powder.
SOLUBILITY:
Soluble in acetic acid.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HAZARD:
MAY BE MUTAGENIC. IRRITANT.
Product Description
Leukotriene biosynthesis inhibitor. Inhibits LTB
4
ω-oxidation.
Product Specific Literature References
Anthralin (1,8-dihydroxyanthrone) is a potent inhibitor of leukotriene production and LTB4-omega oxidation by human neutrophils:
J.M. Schröder; J. Invest. Dermatol.
87
, 624 (1986)
Abstract
Further Categories Containing This Product:
Carcinogens & Tumor Promoters Other Products
•
Cancer Other Products
ALX-260-093
Revised 22-May-06
Antipain
SYNONYMS
[(S)-1-Carboxy-2-phenylethyl]-carbamoyl-Arg-Val-arginal . 2HCl
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
Proteases Other Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-260-093-M005
5 mg
35.00 USD
ALX-260-093-M025
25 mg
130.00 USD
Product Specification
SEQUENCE:
[(S)-1-Carboxy-2-phenylethyl]-carbamoyl-Arg-Val-arginal
FORMULA:
C
27
H
44
N
10
O
6
. 2HCl
MW:
604.7 . 73.0
CAS NUMBER:
37682-72-7
SOURCE/HOST:
Synthetic.
APPEARANCE:
White to off-white powder.
SOLUBILITY:
Soluble in water, methanol, 100 % ethanol or acetonitrile.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Protect from light.
Product Description
Inhibits papain and trypsin and to a small extent plasmin. Antipain is more specific for papain and trypsin than is leupeptin (Prod. No.
ALX-260-009
). The inhibitory potency of antipain is 100-fold higher than that of elastatinal. Acts by forming a hemiacetal adduct between its aldehyde group and the active serine of the proteinase.
Product Specific Literature References
Antipain, a new protease inhibitor isolated from actinomycetes:
H. Suda, et al.; J. Antibiot.
25
, 263 (1972)
Abstract
Structures and activities of protease inhibitors of microbial origin
:
H. Umezawa; Meth. Enzymol.
45
, 678 (1976)
Abstract
ALX-550-036
Revised 17-Jan-05
D-AP3
SYNONYMS
D(-)-2-Amino-3-phosphonopropanoic acid
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
Glutamate Receptors (Metabotropic)/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-550-036-M005
5 mg
75.00 USD
Product Specification
FORMULA:
C
3
H
8
NO
5
P
MW:
169.1
CAS NUMBER:
128241-72-5
PURITY:
≥97%
APPEARANCE:
White powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+4°C
HANDLING:
Protect from light.
Product Specific Literature References
1S,3R-ACPD stimulates and L-AP3 blocks Ca2+ mobilization in rat cerebellar neurons:
A.J. Irving, et al.; Eur. J. Pharmacol.
186
, 363 (1990)
Abstract
Stereoselectivity and mode of inhibition of phosphoinositide-coupled excitatory amino acid receptors by 2-amino-3-phosphonopropionic acid:
D.D. Schoepp, et al.; Mol. Pharmacol.
38
, 222 (1990)
Abstract
Metabotropic glutamate receptors in brain function and pathology:
D.D. Schoepp & P.J. Conn; TIPS
14
, 13 (1993), (Review)
Abstract
Pharmacological agents acting at subtypes of metabotropic glutamate receptors
:
D.D. Schoepp; Neuropharmacology
38
, 1431 (1999), (Review)
Abstract
ALX-550-038
Revised 17-Jan-05
L-AP3
SYNONYMS
L(+)-2-Amino-3-phosphonopropanoic acid
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
Glutamate Receptors (Metabotropic)/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-550-038-M005
5 mg
55.00 USD
ALX-550-038-M025
25 mg
220.00 USD
Product Specification
FORMULA:
C
3
H
8
NO
5
P
MW:
169.1
CAS NUMBER:
23052-80-4
PURITY:
≥97%
APPEARANCE:
White hygroscopic solid.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+4°C
HANDLING:
Protect from light.
Product Description
Selective antagonist of the PI-linked metabotropic glutamate response.
Product Specific Literature References
1S,3R-ACPD stimulates and L-AP3 blocks Ca2+ mobilization in rat cerebellar neurons:
A.J. Irving, et al.; Eur. J. Pharmacol.
186
, 363 (1990)
Abstract
Stereoselectivity and mode of inhibition of phosphoinositide-coupled excitatory amino acid receptors by 2-amino-3-phosphonopropionic acid:
D.D. Schoepp, et al.; Mol. Pharmacol.
38
, 222 (1990)
Abstract
Metabotropic glutamate receptors in brain function and pathology:
D.D. Schoepp & P.J. Conn; TIPS
14
, 13 (1993), (Review)
Abstract
Long-lasting enhancement of NMDA receptor-mediated synaptic transmission by metabotropic glutamate receptor activation:
J.J. O'Connor, et al.; Nature
367
, 557 (1994)
Abstract
Pharmacological agents acting at subtypes of metabotropic glutamate receptors
:
D.D. Schoepp, et al.; Neuropharmacology
38
, 1431 (1999), (Review)
Abstract
ALX-550-037
Revised 17-Jan-05
DL-AP3
SYNONYMS
DL-2-Amino-3-phosphonopropanoic acid
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
NMDA Receptors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-550-037-M050
50 mg
30.00 USD
Product Specification
FORMULA:
C
3
H
8
NO
5
P
MW:
169.1
CAS NUMBER:
20263-06-3
PURITY:
≥97%
APPEARANCE:
White powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+4°C
HANDLING:
Protect from light. Hygroscopic.
Product Description
NMDA receptor antagonist.
Product Specific Literature References
The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations:
R.H. Evans, et al.; Br. J. Pharmacol.
75
, 65 (1982)
Abstract
The metabotropic glutamate receptor antagonist L-2-amino-3-phosphonopropionic acid inhibits phosphoserine phosphatase:
J.E. Hawkinson, et al.; Eur. J. Pharmacol.
307
, 219 (1996)
Abstract
Pharmacological agents acting at subtypes of metabotropic glutamate receptors
:
D.D. Schoepp; Neuropharmacology
38
, 1431 (1999), (Review)
Abstract
ALX-550-024
Revised 26-Nov-04
D-AP4
SYNONYMS
D(-)-2-Amino-4-phosphonobutanoic acid
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
Glutamate Receptors (Metabotropic)/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-550-024-M005
5 mg
70.00 USD
Product Specification
FORMULA:
C
4
H
10
NO
5
P
MW:
183.1
CAS NUMBER:
78739-01-2
PURITY:
≥97%
APPEARANCE:
White powder.
SOLUBILITY:
Soluble in dilute aqueous base.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+4°C
HANDLING:
Protect from light.
Product Description
Broad spectrum excitatory amino acid receptor antagonist.
Product Specific Literature References
The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations:
R.H. Evans, et al.; Br. J. Pharmacol.
75
, 65 (1982)
Abstract
Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord:
J. Davies and J.C. Watkins; Brain Res.
235
, 378 (1982)
Abstract
Further Categories Containing This Product:
Excitatory Amino Acids
ALX-550-026
Revised 27-Nov-04
L-AP4
SYNONYMS
L(+)-2-Amino-4-phosphonobutanoic acid
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
Glutamate Receptors (Metabotropic)/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-550-026-M005
5 mg
65.00 USD
ALX-550-026-M025
25 mg
280.00 USD
Product Specification
FORMULA:
C
4
H
10
NO
5
P
MW:
183.1
CAS NUMBER:
23052-81-5
PURITY:
≥97%
APPEARANCE:
White solid.
SOLUBILITY:
Soluble in dilute aqueous base.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+4°C
HANDLING:
Protect from light.
Product Description
Selective agonist for group III mGluRs.
Product Specific Literature References
Micromolar L-2-amino-4-phosphonobutyric acid selectively inhibits perforant path synapses from lateral entorhinal cortex:
J.F. Koerner & C.W. Cotman; Brain Res.
216
, 192 (1981)
Abstract
Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord:
J. Davies & J.C. Watkins; Brain Res.
235
, 378 (1982)
Abstract
The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations:
R.H. Evans, et al.; Br. J. Pharmacol.
75
, 65 (1982)
Abstract
Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists:
J.C. Watkins, et al.; TIPS
11
, 25 (1990)
Abstract
L-2-amino-4-phosphonobutyrate (L-AP4) is an agonist at the type IV metabotropic glutamate receptor which is negatively coupled to adenylate cyclase:
C. Thomsen, et al.; Eur. J. Pharmacol.
227
, 361 (1992)
Abstract
L-AP4 inhibits calcium currents and synaptic transmission via a G-protein-coupled glutamate receptor:
P.Q. Trombley and G.L. Westbrook; J. Neurosci.
12
, 2043 (1992)
Abstract
Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4- phosphonobutyrate:
Y. Nakajima, et al.; J. Biol. Chem.
268
, 11868 (1993)
Abstract
;
Full Text
Pharmacological agents acting at subtypes of metabotropic glutamate receptors:
D.D. Schoepp, et al.; Neuropharmacology
38
, 1431 (1999), (Review)
Abstract
ALX-550-025
Revised 07-May-03
DL-AP4
SYNONYMS
DL-2-Amino-4-phosphonobutanoic acid
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
NMDA Receptors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-550-025-M050
50 mg
25.00 USD
Product Specification
FORMULA:
C
4
H
10
NO
5
P
MW:
183.1
CAS NUMBER:
20263-07-4
PURITY:
≥97%
APPEARANCE:
White powder.
SOLUBILITY:
Soluble in dilute aqueous base.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+4°C
HANDLING:
Protect from light.
Product Description
First generation NMDA antagonist.
Product Specific Literature References
Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog:
R.H. Evans, et al.; Br. J. Pharmacol.
67
, 591 (1979)
Abstract
2-amino-4-phosphonobutyric acid: a new pharmacological tool for retina research:
M.M. Slaughter and R.F. Miller; Science
211
, 182 (1981)
Abstract
The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations:
R.H. Evans, et al.; Br. J. Pharmacol.
75
, 65 (1982)
Abstract
Anticonvulsant action of 2-amino-7-phosphonoheptanoic acid in the substantia nigra:
G. De Sarro, et al.; Eur. J. Pharmacol.
106
, 175 (1984)
Abstract
ALX-550-033
Revised 07-Aug-07
D-AP5
SYNONYMS
D(-)-2-Amino-5-phosphonopentanoic acid
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
NMDA Receptors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-550-033-M005
5 mg
65.00 USD
ALX-550-033-M025
25 mg
260.00 USD
Product Specification
FORMULA:
C
5
H
12
NO
5
P
MW:
197.1
CAS NUMBER:
79055-68-8
PURITY:
≥97%
APPEARANCE:
White to off-white powder.
SOLUBILITY:
Soluble in water (acidify for better solubility)
