ALEXIS Biochemicals: Sodium butyrate

ALX-270-301

Revised 04-Apr-07

Sodium butyrate
PRODUCT LINE	DNA Regulation / Transcription
PRODUCT CATEGORY	HDAC Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-301-G001		1 g	105.00 USD

Product Specification

FORMULA:	C₄H₇O₂Na
MW:	110.1
CAS NUMBER:	156-54-7
RTECS:	ET6400000
PURITY:	≥99%
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Hygroscopic.
HAZARD:	MAY BE MUTAGENIC. IRRITANT.

Product Description

Short-chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induces apoptosis.

Product Specific Literature References

Sodium butyrate inhibits histone deacetylation in cultured cells: E.P. Candido, et al.; Cell 14, 105 (1978) Abstract
Induction of the differentiated phenotype in human colon cancer cell is associated with the attenuation of subcellular tyrosine phosphorylation: B. Schwartz, et al.; Oncol. Res. 7, 277 (1995) Abstract
Apoptosis induced by the histone deacetylase inhibitor sodium butyrate in human leukemic lymphoblasts: D. Bernhard, et al.; FASEB J. 13, 1991 (1999) Abstract
Sodium Butyrate Induces Transcription from the Galpha i2 Gene Promoter through Multiple Sp1 Sites in the Promoter and by Activating the MEK- ERK Signal Transduction Pathway: J. Yang, et al.; J. Biol. Chem. 276, 25742 (2001) Abstract; Full Text
Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor: M. Nakamura, et al.; J. Cell Physiol. 187, 392 (2001) Abstract
Effects of retinoic acid and sodium butyrate on gene expression, histone acetylation and inhibition of proliferation of melanoma cells: K. Demary, et al.; Cancer Lett. 163, 103 (2001) Abstract

Further Categories Containing This Product:

Apoptosis Inducers & Inhibitors Other Products

another CS2 website

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.