ALEXIS Biochemicals: Sodium fluoride

ALX-400-031

Revised 13-Apr-07

Sodium fluoride
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	G-proteins & GTPases Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-400-031-G025		25 g	20.00 USD

Product Specification

FORMULA:	NaF
MW:	42.0
CAS NUMBER:	7681-49-4
MERCK INDEX:	14: 8618
PURITY:	≥99%
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+20°C
HAZARD:	TOXIC.

Product Description

Fluoride ion (F^-) induces a variety of effects thought to be initiated by stimulation of both stimulatory and inhibitory guanine nucleotide binding proteins (G-proteins) followed by effects of those G-proteins on adenylyl cyclase and other targets. The action of F^- is thought to involve the species [AlF₄]^-, formed by reaction of F^- with aluminium ions leached from glass vessels and/or otherwise present as contaminants in virtually all aqueous media and buffers used in routine biological research. Many studies report an increase in the effects of NaF, or in its potency, when it is supplemented with aluminum salts. Occasional studies report no increase in NaF effects when Al³⁺ is added, presumably due to an already saturating level of aluminium ions in the experimental media.

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