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ALX-630-116 Revised 15-Aug-08
Sterigmatocystin
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SYNONYMS 3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furol[3’,2’:4,5]furo[2,3-c]xanthen-7-one
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-630-116-M001   1 mg 35.00 USD Add To Cart
ALX-630-116-M005   5 mg 120.00 USD Add To Cart
Product Specification
FORMULA: C18H12O6
MW: 324.3
CAS NUMBER: 10048-13-2
RTECS: LV1750000
SOURCE/HOST: Isolated from Aspergillus versicolor.
PURITY: ≥98% (TLC, HPLC)
APPEARANCE: Pale yellow solid.
SOLUBILITY: Soluble in DMSO, 100% ethanol, methanol or acetone.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light.
HAZARD: TOXIC. MAY BE CARCINOGENIC.

Product Description

Mycotoxin produced by strains of the common molds. Inhibitor of DNA synthesis. Induces sister chromatid exchanges in bone marrow cells of mice. Causes necrosis.
Product Specific Literature References
Effect of sterigmatocystin on rat liver nuclear RNA: W. Nel & H.E. Pretorius; Biochem. Pharmacol. 19, 957 (1970) Abstract
Massive and single cell necrosis in the rat liver induced by aflatoxin B1 and sterigmatocystin: K. Terao; Acta Pathol. Jpn. 23, 647 (1973) Abstract
Induction of sister-chromatid exchanges in vivo in mice by the mycotoxins sterigmatocystin and griseofulvin: P.T. Curry, et al.; Mutat. Res. 137, 111 (1984) Abstract
Cytotoxicity of occupationally and environmentally relevant mycotoxins: J. Bünger, et al.; Toxicology 202, 199 (2004) Abstract
An aflatoxin biosynthesis cluster gene encodes a novel oxidase required for conversion of versicolorin a to sterigmatocystin: K.C. Ehrlich, et al.; Appl. Environ. Microbiol. 71, 8963 (2005) Abstract; Full Text
Aspergillus mycotoxins and their effect on the host: K. Kamei & A. Watanabe; Med. Mycol. 43, S95 (2005) Abstract
A novel biosensor for sterigmatocystin constructed by multi-walled carbon nanotubes (MWNT) modified with aflatoxin-detoxifizyme (ADTZ): D.S. Yao, et al.; Bioelectrochemistry 68, 126 (2006) Abstract
Further Categories Containing This Product:
DNA Replication Inhibitors • Non-apoptotic Cell Death/Necrosis
 
 
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