ALEXIS Biochemicals: Sulochrin

ALX-380-221

Revised 14-Nov-07

Sulochrin
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antibiotics for Angiogenesis Research

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-221-M001		1 mg	195.00 USD

Product Specification

FORMULA:	C₁₇H₁₆O₇
MW:	332.3
CAS NUMBER:	519-57-3
SOURCE/HOST:	Isolated from Aspergillus terreus MST-FP1370.
PURITY:	≥99% (HPLC)
APPEARANCE:	Pale yellow solid.
SOLUBILITY:	Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.

Product Description

Fungal metabolite found in a number of Aspergillus and Penicillium sp. Inhibitor of vascular endothelial growth factor (VEGF). Antiangiogenic agent. Inhibits eosinophil activation and chemotaxis.

Product Specific Literature References

Studies in the biochemistry of micro-organisms. 115. Metabolites of Penicillium frequentans Westling: isolation of sulochrin, asterric acid, (+)-bisdechlorogeodin and two new substituted anthraquinones, questin and questinol: A. Mahmoodian and C.E. Stickings; Biochem. J. 92, 369 (1964) Abstract; Full Text
Sulochrin inhibits eosinophil degranulation: H. Ohashi, et al.; J. Antibiot. (Tokyo) 50, 972 (1997) Abstract
Sulochrin inhibits eosinophil activation and chemotaxis: H. Ohashi, et al.; Inflamm. Res. 47, 409 (1998) Abstract
Fungal metabolites, asterric acid derivatives inhibit vascular endothelial growth factor (VEGF)-induced tube formation of HUVECs: H.J. Lee, et al.; J. Antibiot. (Tokyo) 55, 552 (2002) Abstract

Further Categories Containing This Product:

Antibiotics - Immunomodulators • Tyrosine Kinase Inhibitors • VEGFs & VEGF-Rs Other Products

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