ALEXIS Biochemicals: TEMPONE

ALX-430-079

Revised 19-Sep-06

TEMPONE
SYNONYMS	4-Oxo-2,2,6,6-tetramethylpiperidine-1-oxyl 4-Oxo-TEMPO
PRODUCT LINE	Oxidative Stress
PRODUCT CATEGORY	Spin Traps, Spin Probes & Spin Labels

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-430-079-M250		250 mg	15.00 USD
ALX-430-079-M500		500 mg	25.00 USD
ALX-430-079-G001		1 g	40.00 USD

Product Specification

FORMULA:	C₉H₁₆NO₂
MW:	170.2
CAS NUMBER:	2896-70-0
PURITY:	≥98%
APPEARANCE:	Orange crystalline powder.
SOLUBILITY:	Soluble in acetone, DMSO, diethylether, 100% ethanol or water.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.

Product Description

Spin trap, useful for both in vitro and in vivo experiments.

Product Specific Literature References

Cytotoxicity of commonly used nitroxide radical spin probes: E.G. Ankel, et al.; Life Sci. 40, 495 (1987) Abstract
Biologically active metal-independent superoxide dismutase mimics: J.B. Mitchell, et al.; Biochemistry 29, 2802 (1990) Abstract
Superoxide reaction with nitroxides: A. Samuni, et al.; Free Rad. Res. Commun. 9, 241 (1990) Abstract
Inhibition of oxygen-dependent radiation-induced damage by the nitroxide superoxide dismutase mimic, tempol: J.B. Mitchell, et al.; Arch. Biochem. Biophys. 289, 62 (1991) Abstract
Nitrone spin traps and a nitroxide antioxidant inhibit a common pathway of thymocyte apoptosis: A.F. Slater, et al.; Biochem. J. 306, 771 (1995) Abstract
Cytotoxicity of spin trapping compounds: R.F. Haseloff, et al.; FEBS Lett. 418, 73 (1997) Abstract
Characterization of the 4-oxo-2,2,6,6-tetramethylpiperidinooxy dosimeter for in situ radiolysis electron spin resonance studies: K.P. Madden; Radiat. Res. 147, 335 (1997) Abstract
Metabolism of the stable nitroxyl radical 4-oxo-2,2,6, 6-tetramethylpiperidine-N-oxyl (TEMPONE): C. Kroll & H.H. Borchert; Eur. J. Pharm. Sci. 8, 5 (1999) Abstract