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ALX-430-073 Revised 19-Sep-06
TMIO
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SYNONYMS 2,2,4-Trimethyl-2H-imidazole-1-oxide
PRODUCT LINE Oxidative Stress
PRODUCT CATEGORY Spin Traps, Spin Probes & Spin Labels
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-430-073-M050   50 mg 45.00 USD Add To Cart
ALX-430-073-M250   250 mg 180.00 USD Add To Cart
ALX-430-073-G001   1 g 470.00 USD Add To Cart
Product Specification
FORMULA: C6H10N2O
MW: 126.2
PURITY: ≥98%
APPEARANCE: Light yellow crystalline solid.
SOLUBILITY: Soluble in DMSO, water, methanol or 100% ethanol.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic. Protect from light and moisture.

Product Description
Selective, cell permeable and non-toxic spin trap for peroxynitrite and secondary O-, C-, S-, and N- centered free radicals.
Product Specific Literature References
Spin trapping of O-, C-, and S-centered radicals and peroxynitrite by 2H-imidazole-1-oxides: S.I. Dikalov, et al.; BBRC 218, 616 (1996) Abstract
Determination of rate constants of the reactions of thiols with superoxide radical by electron paramagnetic resonance: critical remarks on spectrophotometric approaches: S. Dikalov, et al.; Arch. Biochem. Biophys. 326, 207 (1996) Abstract
Oxygen-centered spin adducts of 5,5-dimethyl-1-pyrroline N-oxide (DMPO) and 2H-imidazole 1-oxides: A.G. Krainev, et al.; J. Magn. Reson. B. 111, 272 (1996) Abstract
Quantification of peroxynitrite, superoxide, and peroxyl radicals by a new spin trap hydroxylamine 1-hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine: S. Dikalov, et al.; BBRC 230, 54 (1997) Abstract
Spin trapping of superoxide radicals and peroxynitrite by 1-hydroxy-3-carboxy-pyrrolidine and 1-hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine and the stability of corresponding nitroxyl radicals towards biological reductants: S. Dikalov, et al.; BBRC 231, 701 (1997) Abstract
Formation of reactive oxygen species in various vascular cells during glyceryltrinitrate metabolism: S. Dikalov, et al.; J. Cardiovasc. Pharmacol. Ther. 3, 51 (1998) Abstract
Reassignment of organic peroxyl radical adducts: S.I. Dikalov & R.P. Mason; Free Radic. Biol. Med. 27, 864 (1999) Abstract
 
 
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