ALEXIS Biochemicals: TMPO

ALX-430-084

Revised 08-Nov-05

TMPO
SYNONYMS	3,3,5,5-Tetramethyl-pyrroline-N-oxide M4PO
PRODUCT LINE	Oxidative Stress
PRODUCT CATEGORY	Spin Traps, Spin Probes & Spin Labels

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-430-084-M100		100 mg	20.00 USD
ALX-430-084-M500		500 mg	70.00 USD

Product Specification

FORMULA:	C₈H₁₅NO
MW:	141.2
PURITY:	≥98%
APPEARANCE:	White to off-white crystalline solid.
SOLUBILITY:	Soluble in water, 100% ethanol, methanol or DMSO.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
HANDLING:	Hygroscopic.

Product Description

Solid cell permeable spin trap.

Product Specific Literature References

Synthesis of spin traps specific for hydroxyl radical: G.M. Rosen & M.J. Turner, 3rd; J. Med. Chem. 31, 428 (1988), (Synthesis) Abstract
The spin trapping of superoxide with M4PO (3,3,5,5-tetramethylpyrroline- N-oxide): G.R. Buettner & B.E. Britigan; Free Rad. Biol. Med. 8, 57 (1990) Abstract
Comparison of 2,5,5-trimethyl-1-pyrroline-N-oxide (M3PO) and 3,3,5,5-tetramethyl-1-pyrroline-N-oxide (M4PO) with 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) as spin traps: M. Nishi, et al.; Biochem. Int. 27, 651 (1992) Abstract
The effect of myoglobin on the stability of the hydroxyl-radical adducts of 5,5 dimethyl-1-pyrolline-N-oxide (DMPO), 3,3,5,5 tetramethyl-1-pyrolline-N-oxide (TMPO) and 1-alpha-phenyl-tert-butyl nitrone (PBN) in the presence of hydrogen : D. De Bono, et al.; Free Radic. Res. 20, 327 (1994) Abstract
Nitrone spin traps and a nitroxide antioxidant inhibit a common pathway of thymocyte apoptosis: A.F. Slater, et al.; Biochem. J. 306, 771 (1995) Abstract

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