ALEXIS Biochemicals: Tenuazonic acid

ALX-350-317

Revised 08-Apr-08

Tenuazonic acid
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antitumor Antibiotics

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-317-MC05		0.5 mg	150.00 USD

Product Specification

FORMULA:	C₁₀H₁₅NO₃
MW:	197.3
CAS NUMBER:	610-88-8
MERCK INDEX:	14: 9149
RTECS:	UY7425000
SOURCE/HOST:	Isolated from Alternaria sp.
PURITY:	≥97% (HPLC)
APPEARANCE:	Brown oily solid.
SOLUBILITY:	Soluble in DMSO or 100% ethanol.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.
IDENTITY:	Identity determined by ¹H-NMR, ¹³C-NMR and MS.

Product Description

Antineoplastic compound exhibiting antitumor, antiviral and antibacterial activity. Inhibits protein synthesis by suppression at the ribosome. May act as a mycotoxin.

Product Specific Literature References

Microbial metabolites with insecticidal properties: M. Cole & G.N. Rolinson; Appl. Microbiol. 24, 660 (1972) Abstract
Microbial production of tenuazonic acid analogues: S. Gatenbeck & J. Sierankiewicz; Antimicrob. Agents Chemother. 3, 308 (1973) Abstract
Inhibition of mouse skin tumor promotion by tenuazonic acid: M. Antony, et al.; Cancer Lett. 61, 21 (1991) Abstract

Further Categories Containing This Product:

Mycotoxins • Antitumor Agents (Anti-proliferative) • Antibiotics - Antiviral/Anti-HIV

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