ALEXIS Biochemicals: Tetrodotoxin (citrate free)

ALX-630-002

Revised 20-Nov-07

Tetrodotoxin (citrate free)
SYNONYMS	Fugu poison TTX
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Neurotoxins

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-630-002-M001		1 mg

Product Specification

FORMULA:	C₁₁H₁₇N₃O₈
MW:	319.3
CAS NUMBER:	4368-28-9
MERCK INDEX:	14: 9246
RTECS:	IO1450000
SOURCE/HOST:	Isolated from ovaries and liver of chinese puffer fish.
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in dilute acetic acid or citrate buffer (pH 4.8–4.9). Do not use alkaline solution.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C
HANDLING:	Do not use in alkaline media.
HAZARD:	VERY TOXIC.

Product Description

Potent neurotoxin. Blocks voltage-gated fast Na⁺ channels in nerve cell membranes.

Product Specific Literature References

The constituents of the ovaries of globefish. VIII. Studies on tetrodotoxin: K. Tsuda & M. Kawamura; Pharm. Bull. 1, 112 (1953) Abstract
Recent advances in the study of mechanism of action of marine neurotoxins: T. Narahashi, et al.; Neurotoxicology 15, 545 (1994), (Review) Abstract
Tetrodotoxin poisoning: D.F. Hwang & T. Noguchi; Adv. Food Nutr. Res. 52, 141 (2007), (Review) Abstract

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