ALEXIS Biochemicals: Tie-2 Inhibitor 13

ALX-270-434

Revised 18-Apr-06

Tie-2 Inhibitor 13
SYNONYMS	(1Z)-5-Fluoro-2-methyl-1-(3-thienylmethylene)-1H-indene-3-acetic acid
PRODUCT LINE	Cancer
PRODUCT CATEGORY	Angiopoietins & Tie Receptors/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-434-M001		1 mg	110.00 USD

Product Specification

FORMULA:	C₁₇H₁₃FO₂S
MW:	300.6
CAS NUMBER:	857250-95-4
PURITY:	≥95%
APPEARANCE:	Yellow solid.
SOLUBILITY:	Soluble in DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 6 months when stored at -20°C in the dark.
HANDLING:	Protect from light.
IDENTITY:	Identity determined by ¹H-NMR, ¹³C-NMR and MS.

Product Description

Potent and cell permeable Tie-2 inhibitor (IC₅₀=600nm).

Product Specific Literature References

Inhibition of angiogenesis-relevant receptor tyrosine kinases by sulindac analogues: E. Gourzoulidou, et al.; Chembiochem. 6, 527 (2005) Abstract
Endothelial survival factors and spatial completion, but not pericyte coverage of retinal capillaries determine vessel plasticity: J. Hoffmann, et al.; FASEB J. 19, 2035 (2005) Abstract

another CS2 website

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