ALEXIS Biochemicals: Trans-24

ALX-270-439

Revised 18-Sep-06

Trans-24
SYNONYMS	(5R,11aS)-2-Benzyl-5-(3-hydroxyphenyl)-6H-1,2,3,5,11,11a-hexahydroimidazo[1,5-b]-β-carboline-1,3-dione
PRODUCT LINE	Cell Cycle
PRODUCT CATEGORY	Cell Cycle Blockers & Inhibitors / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-439-M001		1 mg	75.00 USD

Product Specification

FORMULA:	C₂₆H₂₁N₃O₃
MW:	423.5
CAS NUMBER:	869304-55-2
PURITY:	≥95%
APPEARANCE:	Yellow solid.
SOLUBILITY:	Soluble in DMSO (10mg/ml).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 6 months when stored at -20°C in the dark.
HANDLING:	Protect from light.
HAZARD:	HARMFUL.
IDENTITY:	Identity determined by ¹H-NMR, ¹³C-NMR and MS.

Product Description

Potent, cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC₅₀=650nM) by binding to the mitotic kinesin Eg5.

Product Specific Literature References

Synthesis and biological evaluation of new tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin Eg5: N. Sunder-Plassmann, et al.; Bioorg. Med. Chem. 13, 6094 (2005) Abstract

Further Categories Containing This Product:

Kinesin & Kinesin-like Proteins / Related Products

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