ALEXIS Biochemicals: Trichostatin C

ALX-380-239

Revised 19-Feb-08

Trichostatin C
SYNONYMS	Antibiotic 145-A
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Other Antibiotics - DNA Regulation / Transcription

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-239-MC05		0.5 mg	360.00 USD

Product Specification

FORMULA:	C₂₃H₃₂N₂O₈
MW:	464.5
CAS NUMBER:	68676-88-0
MERCK INDEX:	14: 9649
SOURCE/HOST:	Isolated from Streptomyces sp. MST-AS5376.
PURITY:	≥95% (HPLC)
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in methanol or DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Analog of trichostatin A (Prod. No. ALX-380-068). Induces acetylation of histone H4. Shows antifungal activity.

Product Specific Literature References

Trichostatin C, a glucopyranosyl hydroxamate: N. Tsuji and M. Kobayashi: N. Tsuji and M. Kobayashi; J. Antibiot. (Tokyo) 31, 939 (1978) Abstract
Effects of trichostatins on differentiation of murine erythroleukemia cells: M. Yoshida, et al.; Cancer Res. 47, 3688 (1987) Abstract; Full Text
Promotion of antigen-specific antibody production in murine B cells by a moderate increase in histone acetylation: T. Kohge, et al.; Biochem. Pharmacol. 56, 1359 (1998) Abstract

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Antibiotics - Antifungal

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