ALEXIS Biochemicals: Tyrphostin AG 1478

ALX-270-036

Revised 06-Jun-08

Tyrphostin AG 1478
SYNONYMS	4-(3-Chloroanilino)-6,7-dimethoxyquinazoline
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Tyrphostins

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-036-M001		1 mg	30.00 USD
ALX-270-036-M005		5 mg	80.00 USD

Product Specification

FORMULA:	C₁₆H₁₄ClN₃O₂
MW:	315.8
CAS NUMBER:	175178-82-2
PURITY:	≥98% (HPLC)
APPEARANCE:	White to light yellow solid.
SOLUBILITY:	Soluble in DMSO (10mg/ml).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Packaged under inert gas. Protect from light.

Product Specific Literature References

Role of heparin-binding EGF-related peptides in proliferation and apoptosis of activated ras-stimulated intestinal epithelial cells: S. Zushi, et al.; Int. J. Cancer 73, 917 (1997) Abstract
Inhibition of epidermal growth factor receptor kinase induces protease- dependent apoptosis in human colon cancer cells: W.E. Karnes, et al.; Gastroenterology 114, 930 (1998) Abstract
Apoptosis and growth inhibition of head and neck tumor cell line induced by epidermal growth factor receptor tyrosine kinase inhibitor: R.A. Faust, et al.; Oral Oncol. 35, 290 (1999) Abstract
Inhibition of epidermal-growth-factor-receptor-dependent signalling by tyrphostins A25 and AG1478 blocks growth and induces apoptosis in colorectal tumor cells in vitro: G. Partik, et al.; J. Cancer Res. Clin. Oncol. 125, 379 (1999) Abstract

Further Categories Containing This Product:

EGFR Kinase Inhibitors

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