ALEXIS Biochemicals: U-46619

ALX-340-015

Revised 08-Jul-08

U-46619
SYNONYMS	9,11-Dideoxy-9α,11α-methanoepoxy prostaglandin F_2α
PRODUCT LINE	Inflammation
PRODUCT CATEGORY	Thromboxanes / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-340-015-M001		1 mg	94.00 USD
ALX-340-015-M005		5 mg	422.00 USD

Product Specification

FORMULA:	C₂₁H₃₄O₄
MW:	350.5
CAS NUMBER:	56985-40-1
CONCENTRATION:	10mg/ml
PURITY:	≥98%
FORMULATION:	Liquid. Solution in methyl acetate.
SOLUBILITY:	100mg/ml soluble in 100% ethanol, DMSO or dimethyl formamide; 2mg/ml soluble in PBS, pH 7.2.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 2 years after receipt when stored at -20°C. We do not recommend storing aqueous solutions for more than one day.

Product Description

Prostaglandin H₂/thromboxane A₂ receptor agonist; stable analog of thromboxane A₂.

Product Specific Literature References

Comparison of the actions of U-46619, a prostaglandin H2-analogue, with those of prostaglandin H2 and thromboxane A2 on some isolated smooth muscle preparations: R.A. Coleman, et al.; Br. J. Pharmacol. 73, 773 (1981) Abstract
Responsiveness of platelets and coronary arteries from different species to synthetic thromboxane and prostaglandin endoperoxide analogues: S.E. Burke, et al.; Br. J. Pharmacol. 78, 287 (1983) Abstract
Binding of a thromboxane A2/prostaglandin H2 agonist [3H]U46619 to washed human platelets: N. Liel, et al.; Prostaglandins 33, 789 (1987) Abstract
Heterogeneity of thromboxane A2 (TP-) receptors: evidence from antagonist but not agonist potency measurements: P.M. Tymkewycz, et al.; Br. J. Pharmacol. 102, 607 (1991) Abstract

General Information

BACKGROUND/TECHNICAL INFORMATION

To change the solvent, evaporate the methyl acetate under a gentle stream of nitrogen and immediately add the solvent of choice.

Further Categories Containing This Product:

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