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ALX-350-102 Revised 25-Mar-08
Vindoline
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SYNONYMS (2β,3β,4β,5α,12β,19α)-4-(Acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carbox
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Natural Products for Cytoskeletal Research
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-350-102-M100   100 mg 160.00 USD Add To Cart
ALX-350-102-G001   1 g 430.00 USD Add To Cart
Product Specification
FORMULA: C25H32N2O6
MW: 456.5
CAS NUMBER: 2182-14-1
MERCK INDEX: 14: 9988
SOURCE/HOST: Isolated from Catharanthus roseus.
PURITY: ≥90%
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in 100% ethanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Very hygroscopic.

Product Description
Lacks physiological activity itself, but is contained as the pentacyclic moiety in the antineoplastic agents vinblastine and vincristine.
Product Specific Literature References
Photochemical one-pot synthesis of vinblastine and vincristine: S. Pennanen & A. Huhtikangas; Photochem. Photobiol. 51, 515 (1990) Abstract
Mechanism of interaction of vinca alkaloids with tubulin: catharanthine and vindoline: V. Prakash & S.N. Timasheff; Biochemistry 30, 873 (1991) Abstract
Antimitotic agents: chemistry and recognition of tubulin molecule: S. Iwasaki; Med. Res. Rev. 13, 183 (1993) Abstract
Catharanthus roseus L. plants and explants infected with phytoplasmas: alkaloid production and structural observations: M.A. Favali, et al.; Protoplasma 223, 45 (2004) Abstract
 
 

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