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Angiotensin Converting Enzyme [ACE] & ACE2 / Related Products
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AG-AE0631 Revised 11-Jan-08
ACE2 (human) ELISA Kit
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SYNONYMS Angiotensin-converting Enzyme 2 (human) ELISA Kit
SARS Receptor (human) ELISA Kit
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Angiotensin Converting Enzyme [ACE] & ACE2 / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
AG-AE0631EK-KI01   96 wells 590.00 USD Add To Cart
AG-AE0631TP-KI01 Twin Plex 2x96 wells 890.00 USD Add To Cart
AG-AE0631PP-KI01 Penta Plex 5x96 wells 1'870.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY: 293pg/ml (range 0 to 50ng/ml)
APPLICATION: For the quantitative determination of ACE2 in human urine samples or cell culture supernatants.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
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General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
SARS Coronavirus / Related Products • ELISA & EIA Kits
 
 
ALX-201-330 Revised 24-Jul-06
ACE2 (human):Fc (human) (recombinant)
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SYNONYMS Angiotensin-converting Enzyme 2 (human):Fc (human) (recombinant)
SARS Receptor (human):Fc (human) (recombinant)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Angiotensin Converting Enzyme [ACE] & ACE2 / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-330-C050   50 µg 370.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. The signal peptide sequence and the extracellular domain of human ACE2 (angiotensin-converting enzyme 2) (aa 1-740) are fused at the C-terminus to the Fc portion of human IgG1.
CONCENTRATION: 1mg/ml
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL test).
BIOLOGICAL ACTIVITY: Converts angiotensin I to angiotensin-(1-9).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
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General Information
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link Q9NRA7: Angiotensin converting enzyme-like protein (human)
MANUFACTURER Manufactured by Adipogen, Inc.
Further Categories Containing This Product:
SARS Coronavirus / Related Products • Recombinant Proteins / Fusion Proteins
 
 
ALX-201-356 Revised 18-Mar-08
ACE2, Soluble (human) (recombinant)
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SYNONYMS Angiotensin-converting Enzyme 2, Soluble (human) (recombinant)
SARS Receptor, Soluble (human) (recombinant)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Angiotensin Converting Enzyme [ACE] & ACE2 / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-356-C010   10 µg 295.00 USD Add To Cart
ALX-201-356-C050   50 µg 795.00 USD Add To Cart
Product Specification
EC: 3.4.17.-
SOURCE/HOST: Produced in HEK 293 cells. The signal peptide sequence and the extracellular domain of human ACE2 (angiotensin-converting enzyme 2) (aa 1-740) are fused at the C-terminus to a FLAG®-tag.
CONCENTRATION: 1mg/ml
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
BIOLOGICAL ACTIVITY: Converts angiotensin I to angiotensin-(1-9).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q9NRA7: Angiotensin converting enzyme-like protein (human)

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
SARS Coronavirus / Related Products • Recombinant Proteins / Fusion Proteins
 
 
ALX-270-212 Revised 26-Jan-07
Captopril
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SYNONYMS (2S)-1-(3-Mercapto-2-methylpropionyl)-L-proline
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Angiotensin Converting Enzyme [ACE] & ACE2 / Related Products
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ALX-270-212-G001   1 g 20.00 USD Add To Cart
ALX-270-212-G005   5 g 70.00 USD Add To Cart
Product Specification
FORMULA: C9H15NO3S
MW: 217.3
CAS NUMBER: 62571-86-2
MERCK INDEX: 14: 1774
RTECS: UY0550000
PURITY: ≥98% (Assay)
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in water, chloroform, dichloromethane or 100% ethanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HAZARD: MAY BE TERATOGENIC. HARMFUL.

Product Description
First orally active angiotensin-converting enzyme (ACE) inhibitor. Reversible and competitive inhibitor of LTA4 hydrolase. Inhibits angiogenesis. Antihypotensive agent.
 
 
ALX-260-008 Revised 26-Jan-05
Foroxymithine
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SYNONYMS (3S,6S)-3-[3-[N-[N-(Nα-Acetyl-Nδ-formyl-Nδ-hydroxy-L-ornithyl)-L-seryl-N-(hydroxy)amino]propyl]-6-[3-(N-formyl-N-hydroxyamino)propyl]-2,5-piperazinedione
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Angiotensin Converting Enzyme [ACE] & ACE2 / Related Products
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ALX-260-008-M001   1 mg 90.00 USD Add To Cart
Product Specification
FORMULA: C22H37N7O11
MW: 575.6
CAS NUMBER: 100157-28-6
SOURCE/HOST: Microbial.
PURITY: ≥98%
APPEARANCE: Off-white solid.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Inhibitor of angiotensin I converting enzyme.
Product Specific Literature References
Influence of angiotensin-converting enzyme inhibitor, foroxymithine, on dynamic equilibrium around the renin-angiotensin system in vivo: T. Aoyagi, et al.; J. Appl. Biochem. 7, 388 (1985) Abstract
Foroxymithine, a new inhibitor of angiotensin-converting enzyme, produced by actinomycetes: H. Umezawa, et al.; J. Antibiot. (Tokyo) 38, 1813 (1985) Abstract
 
 
ALX-804-722 Revised 31-Aug-06
Monoclonal Antibody to ACE2 (human) (AC384)
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SYNONYMS anti-Angiotensin-converting Enzyme 2 (human) MAb (AC384)
anti-SARS Receptor (human) MAb  (AC384)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Angiotensin Converting Enzyme [ACE] & ACE2 / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-722-C050   50 µg 195.00 USD Add To Cart
ALX-804-722-C100   100 µg 270.00 USD Add To Cart
ALX-804-722B-C050 Biotin 50 µg 380.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: AC384
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant human ACE2 (angiotensin-converting enzyme 2).
SPECIFICITY: Recognizes human ACE2.
APPLICATION: ELISA (direct and indirect: 1:2’000-1:10’000)
Western Blot (1:2’000-1:10’000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature)
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles.
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General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
SARS Coronavirus / Related Products • Monoclonal Antibodies
 
 
ALX-804-715 Revised 19-Jun-08
Monoclonal Antibody to ACE2 (human) (AC18F)
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SYNONYMS anti-Angiotensin-converting Enzyme 2 (human) MAb (AC18F)
anti-SARS Receptor (human) MAb (AC18F)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Angiotensin Converting Enzyme [ACE] & ACE2 / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-715-C050   50 µg 195.00 USD Add To Cart
ALX-804-715-C100   100 µg 270.00 USD Add To Cart
ALX-804-715B-C050 Biotin 50 µg 380.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: AC18F
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant human ACE2 (angiotensin-converting enzyme 2).
SPECIFICITY: Recognizes human ACE2.
APPLICATION: ELISA (direct and indirect: 1:2’000-1:10’000)
Flow Cytometry
Western Blot (1:2’000-1:10’000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature)
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
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Product Specific Literature References
Co-localization of angiotensin-converting enzyme 2-, octomer-4- and CD34 positive cells in rabbit atherosclerotic plaques: A. Zulli, et al.; Exp. Physiol. 93, 564 (2008) Abstract
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
SARS Coronavirus / Related Products • Monoclonal Antibodies
 
 
ALX-270-213 Revised 13-Dec-06
S-Nitrosocaptopril
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Angiotensin Converting Enzyme [ACE] & ACE2 / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-270-213-M010   10 mg 60.00 USD Add To Cart
ALX-270-213-M050   50 mg 240.00 USD Add To Cart
Product Specification
FORMULA: C9H14N2O4S
MW: 246.3
PURITY: ≥98%
APPEARANCE: Red crystals.
SOLUBILITY: Soluble in water or 100% ethanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HANDLING: Protect from light.

Product Description
Angiotensin-converting enzyme (ACE) inhibitor. Inhibitor of platelet aggregation. Its activity may depend on the homolytic cleavage of the S-N bond under physiological conditions, yielding nitric oxide (NO) and the parent compound, captopril (Prod. No. ALX-270-212).
Product Specific Literature References
S-nitrosocaptopril. I. Molecular characterization and effects on the vasculature and on platelets: J. Loscalzo, et al.; J. Pharmacol. Exp. Ther. 249, 726 (1989) Abstract
S-nitrosocaptopril. II. Effects on vascular reactivity: J.P. Cooke, et al.; J. Pharmacol. Exp. Ther. 249, 730 (1989) Abstract
The hemodynamic effects of S-nitrosocaptopril in anesthetized dogs: J.E. Shaffer, et al.; J. Pharmacol. Exp. Ther. 256, 704 (1991) Abstract
Dual role of S-nitrosocaptopril as an inhibitor of angiotensin-converting enzyme and a nitroso group carrier: J.W. Park; BBRC 189, 206 (1992) Abstract
Differential inhibition of platelet aggregation and calcium mobilization by nitroglycerin and stabilized nitric oxide: M. Amano, et al.; J. Cardiovasc. Pharmacol. 24, 860 (1994) Abstract
Vasorelaxing effect of S-nitrosocaptopril on dog coronary arteries: no cross-tolerance with nitroglycerin: T. Matsumoto, et al.; J. Pharmacol. Exp. Ther. 275, 1247 (1995) Abstract
The effects of S-nitrosocaptopril on canine coronary circulation: I. Nakae, et al.; J. Pharmacol. Exp. Ther. 274, 40 (1995) Abstract
The effects of S-nitrosocaptopril on renal filtration and blood pressure in rats: L. Jia & R.C. Blantz; Eur. J. Pharmacol. 354, 33 (1998) Abstract
Physicochemistry, pharmacokinetics, and pharmacodynamics of S-nitrosocaptopril crystals, a new nitric oxide donor: L. Jia, et al.; J. Pharm. Sci. 88, 981 (1999) Abstract
Antiangiogenic effects of S-nitrosocaptopril crystals as a nitric oxide donor: L. Jia, et al.; Eur. J. Pharmacol. 391, 137 (2000) Abstract
In vitro and in vivo assessment of cellular permeability and pharmacodynamics of S-nitrosylated captopril, a nitric oxide donor: L. Jia & H. Wong; Br. J. Pharmacol. 134, 1697 (2001) Abstract
S-nitrosocaptopril: in vitro characterization of pulmonary vascular effects in rats: D.Y. Tsui, et al.; Br. J. Pharmacol. 138, 855 (2003) Abstract
S-nitrosocaptopril: acute in-vivo pulmonary vasodepressor effects in pulmonary hypertensive rats: D.Y. Tsui, et al.; J. Pharm. Pharmacol. 55, 1121 (2003) Abstract
Further Categories Containing This Product:
Nitric Oxide Donors
 
 
ALX-210-444 Revised 25-Jul-07
Polyclonal Antibody to ACE2 (human)
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SYNONYMS anti-Angiotensin-converting Enzyme 2 (human) PAb
anti-SARS Receptor (human) PAb
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Angiotensin Converting Enzyme [ACE] & ACE2 / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-444-C100   100 µg 340.00 USD Add To Cart
ALX-210-444B-C050 Biotin 50 µg 340.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml.
PURITY DETAIL: Purified IgG.
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant human ACE2 (angiotensin-converting enzyme 2).
SPECIFICITY: Recognizes human ACE2.
APPLICATION: ELISA (direct and indirect: 1:2’000-1:10’000)
Western Blot 1:2’000-1:10’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
SARS Coronavirus / Related Products • Polyclonal Antibodies
 
 
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