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ALX-350-145
Revised 28-Mar-07
Isobavachalcone
SYNONYMS
2’,4’,4-Trihydroxy-3’-[3’’-methylbut-3’’-enyl]chalcone
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Natural Products - Antitumor Reagents
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-350-145-M001
1 mg
190.00 USD
Product Specification
FORMULA:
C
20
H
20
O
4
MW:
324.4
CAS NUMBER:
20784-50-3
SOURCE/HOST:
Isolated from plant
Psoralea corylifolia
.
PURITY:
≥97% (HPLC)
APPEARANCE:
Yellow oil.
SOLUBILITY:
Soluble in DMSO or 100% ethanol.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Protect from light.
IDENTITY:
Determined by
1
H-NMR,
13
C-NMR and MS.
Product Description
Inhibits platelet aggregation. Inhibitor of Epstein-Barr virus early antigen (EBV-EA) induction. Exhibits potent inhibitory effect on skin tumor promotion. Potent inhibitor of MMP-2. Displays DNA strand-scission (cleaving) activity. Shows antifungal activity.
Product Specific Literature References
Antiplatelet flavonoids from seeds of Psoralea corylifolia:
W.J. Tsai, et al.; J. Nat. Prod.
59
, 671 (1996)
Abstract
Antioxidative components of Psoralea corylifolia (Leguminosae):
H. Haraguchi, et al.; Phytother. Res.
16
, 539 (2002)
Abstract
Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects:
T. Akihisa, et al.; Cancer Lett.
201
, 133 (2003)
Abstract
Antitrichomonal and antioxidant activities of Dorstenia barteri and Dorstenia convexa:
N.O. Omisore, et al.; Braz. J. Med. Biol. Res.
38
, 1087 (2005)
Abstract
Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects:
T. Akihisa, et al.; J. Nat. Prod.
69
, 38 (2006)
Abstract
Inhibition of matrix metalloproteinase-2 secretion by chalcones from the twigs of Dorstenia barteri Bureau.:
B. Ngameni, et al.; Arkivoc
ix
, 91 (2007)
Full Text
Further Categories Containing This Product:
Other Natural Products - DNA Regulation / Transcription
•
Chalcones
•
Antithrombotic Agents / Platelet Aggregation Inhibitors / Related Products
•
MMP Inhibitors
•
Epstein Barr Virus / Related Products
•
Antitumor Agents (Anti-proliferative)
•
Natural Products - Antifungal Agents
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