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ALX-210-240
Revised 16-Mar-07
Polyclonal Antibody to Caveolin-2
PRODUCT LINE
Protein Synthesis, Modification & Degradation
PRODUCT CATEGORY
Caveolae / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-240-C100
100 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
Rat
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 1-19 (M
1
GLETEKADVQLF
MADDAY
19
C) of rat caveolin-2.
SPECIFICITY:
Recognizes mouse and rat caveolin-2. Detects a band of ~21kDa by Western blot. Does not cross-react with caveolin-1 or -3.
APPLICATION:
Immunoprecipitation
Western Blot (2µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-153-029
.
Product Images
Please click on thumbnails to enlarge.
Further Categories Containing This Product:
NOS Regulation
•
Polyclonal Antibodies
ALX-210-888
Revised 25-May-07
Polyclonal Antibody to Caveolin-2 (mouse) (phosphorylated) (pTyr19)
PRODUCT LINE
Protein Synthesis, Modification & Degradation
PRODUCT CATEGORY
Caveolae / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-888-C100
100 µg
385.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST:
From rabbit.
PURITY DETAIL:
Epitope-affinity purified.
FORMULATION:
Liquid. Contains 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 14-25 (M
14
ADDApYSHHSGC
25
) of mouse caveolin-2 phosphorylated at Tyr
19
.
SPECIFICITY:
Recognizes mouse phosphorylated caveolin-2. Detects a band of ~21kDa by Western blot.
APPLICATION:
Immunocytochemistry (5µg/ml)
Western Blot (2µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-153-060
.
Related Products
ALX-153-060
Blocking Peptide for PAb to Caveolin-2 (mouse) (phosphorylated) (pTyr
19
) (Prod. No.
ALX-210-888
)
Further Categories Containing This Product:
Phospho-specific Antibodies
•
NOS Regulation
•
Polyclonal Antibodies
ALX-210-241
Revised 24-Apr-08
Polyclonal Antibody to Caveolin-3
PRODUCT LINE
Protein Synthesis, Modification & Degradation
PRODUCT CATEGORY
Caveolae / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-241-C100
100 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
Rat
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml
PURITY DETAIL:
Epitope affinity-purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 1-18 (M
1
MTEEHTDLEARIIKDIH
18
C) of rat caveolin-3.
SPECIFICITY:
Recognizes mouse and rat caveolin-3. Detects a band of ~21kDa by Western blot. Does not cross-react with caveolin-1 or -2.
APPLICATION:
Immunocytochemistry
Immunoprecipitation
Western Blot (1µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-153-030
.
Product Images
Please click on thumbnails to enlarge.
Further Categories Containing This Product:
NOS Regulation
•
Polyclonal Antibodies
ALX-210-641
Revised 25-Sep-07
Polyclonal Antibody to CCR3 (mouse)
SYNONYMS
anti-C-C Chemokine Receptor 3 (mouse) PAb
anti-Eotaxin Receptor (mouse) PAb
anti-CD193 (mouse) PAb
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-641-C200
200 µg
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST:
From goat.
CONCENTRATION:
2mg/ml.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 5-29 (T
5
DEIKTVVESFETTPYEYEWAPPC
28
) of the N-terminal extracellular domain of mouse CCR3 (C-C Chemokine Receptor 3).
SPECIFICITY:
Recognizes mouse CCR3.
APPLICATION:
Immunocytochemistry (>1:400)
Immunohistochemistry (paraffin sections (>1:250))
Western Blot (>1:1’000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-153-066
.
Product Images
Please click on thumbnails to enlarge.
Related Products
ALX-153-066
Blocking Peptide for PAb to CCR3 (mouse) (Prod. No.
ALX-210-641
)
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-741
Revised 25-Jan-07
Polyclonal Antibody to CCR1 (human)
SYNONYMS
anti-C-C Chemokine Receptor 1 (human) PAb
anti-CD191 (human) PAb
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-741-R100
100 µl
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
PURITY DETAIL:
Epitope-affinity purified F(ab`)2 fragments.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 7-24 (T
7
EDYDTTTEFDY
GDATPC
24
) of the N-terminal extracellular domain of human CCR1 (C-C chemokine receptor 1).
SPECIFICITY:
Recognizes human CCR1. Does not cross-react with mouse CCR1.
APPLICATION:
Immunocytochemistry (1:400)
Immunohistochemistry (paraffin sections)
Western Blot (1:1’000)
Optimal working conditions must be determined individually for each application.
QUALITY CONTROL:
Immunocytochemistry on human peripheral blood leukocytes.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
For maximum product recovery after thawing, centrifuge the vial before opening the cap. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-153-019
.
Product Description
CCR1 is a receptor for macrophage inflammatory protein-1α (MIP-1α) and RANTES, expressed in peripheral blood lymphocytes and monocytes (but not neutrophils). The antibody is useful in determining the number of CCR1 positive cells and in detecting any changes in the level of CCR1 expression in cells present at the site of inflammation.
Product Specific Literature References
Preparation of specific polyclonal antibodies to a C-C chemokine receptor, CCR1, and determination of CCR1 expression on various types of leukocytes
:
S.B. Su, et al.; J. Leukoc. Biol.
60
, 658 (1996)
Abstract
General Literature References
Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor
:
K. Neote, et al.; Cell
72
, 415 (1993)
Abstract
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-620
Revised 25-Jan-07
Polyclonal Antibody to CCR1 (human)
SYNONYMS
anti-C-C Chemokine Receptor 1 (human) PAb
anti-CD191 (human) PAb
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-620-C200
200 µg
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From goat.
CONCENTRATION:
1mg/ml.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 7-24 (T
7
EDYDTTTEFDY
GDATPC
24
) of the N-terminal extracellular domain of human CCR1 (C-C chemokine receptor 1).
SPECIFICITY:
Recognizes human CCR1. Does not cross-react with mouse CCR1.
APPLICATION:
Immunocytochemistry (1:400)
Western Blot (1:1’000)
QUALITY CONTROL:
Immunocytochemistry on human peripheral blood leukocytes.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-153-019
.
Product Description
CCR1 is a receptor for macrophage inflammatory protein-1α (MIP-1α) and RANTES, expressed in peripheral blood lymphocytes and monocytes (but not neutrophils). The antibody is useful in determining the number of CCR1 positive cells and in detecting any changes in the level of CCR1 expression in cells present at the site of inflammation.
General Literature References
Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor
:
K. Neote, et al.; Cell
72
, 415 (1993)
Abstract
Related Products
ALX-153-019
Blocking Peptide for PAb to CCR1 (human) (Prod. No.
ALX-210-620
and
ALX-210-741
)
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-821
Revised 12-Apr-06
Polyclonal Antibody to CCR2 (human)
SYNONYMS
anti-C-C Chemokine Receptor 2 (human) PAb
anti-CD192 (human) PAb
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-821-C200
200 µg
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From goat.
CONCENTRATION:
2mg/ml.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 17-39 (G
17
EEVTTFFDYDYGAPCHKFDVKQ
39
) of the N-terminal extracellular domain of human CCR2 (C-C chemokine receptor 2).
SPECIFICITY:
Recognizes human CCR2.
APPLICATION:
Immunocytochemistry (1:400)
Immunohistochemistry (paraffin sections (1:200))
Western Blot (1:1’000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-153-036
.
General Literature References
Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails
:
I.F. Charo, et al.; PNAS
91
, 2752 (1994)
Abstract
;
Full Text
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-640
Revised 25-Sep-07
Polyclonal Antibody to CCR2 (mouse)
SYNONYMS
anti-C-C Chemokine Receptor 2 (mouse) PAb
anti-CD192 (mouse) PAb
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-640-C200
200 µg
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST:
From goat.
CONCENTRATION:
2mg/ml.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 18-45 (S
18
HSLFTRSIQELDEGATTPYDYDDGEPC
45
) of the N-terminal extracellular domain of mouse CCR2 (C-C chemokine receptor 2).
SPECIFICITY:
Recognizes mouse CCR2.
APPLICATION:
Immunocytochemistry (1:400)
Immunohistochemistry (paraffin sections (1:250))
Western Blot (1:1’000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-153-065
.
Product Images
Please click on thumbnails to enlarge.
Related Products
ALX-153-065
Blocking Peptide for PAb to CCR2 (human) (Prod. No.
ALX-210-640
)
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-822
Revised 08-Dec-06
Polyclonal Antibody to CCR3 (human)
SYNONYMS
anti-C-C Chemokine Receptor 3 (human) PAb
anti-Eotaxin Receptor (human) PAb
anti-CD193 (human) PAb
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-822-C200
200 µg
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From goat.
CONCENTRATION:
2mg/ml.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 8-34 (V
8
ETFGTTSYYDDVGLLCEKADTRALMA
34
) of the N-terminal extracellular domain of human CCR3 (C-C Chemokine Receptor 3).
SPECIFICITY:
Recognizes human CCR3.
APPLICATION:
Immunocytochemistry (1:400)
Immunohistochemistry (paraffin sections (1:250))
Western Blot (1:1’000)
QUALITY CONTROL:
Immunocytochemistry on human peripheral blood or Immunohistochemistry on paraffin sections of human spleen.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
After opening, prepare aliquots and store at -20°C. For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-153-037
.
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-622
Revised 31-Jul-07
Polyclonal Antibody to CCR4 (human)
SYNONYMS
anti-C-C Chemokine Receptor 4 (human) PAb
anti-CD194 (human) PAb
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-622-C200
200 µg
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From goat.
CONCENTRATION:
2mg/ml.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 18-39 (S
18
NYYLYESIPK
PCTKEGIKAFGE
39
) of human CCR4 (C-C chemokine receptor 4).
SPECIFICITY:
Recognizes human CCR4.
APPLICATION:
Immunocytochemistry (acetone fixed cells (1:400))
Immunohistochemistry (paraffin sections (1:200))
Western Blot (1:1’000)
QUALITY CONTROL:
Immunocytochemistry on mouse spleen cells.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-153-061
.
Product Images
Please click on thumbnails to enlarge.
General Information
Mouse CCR4 is the homolog of human CCR4 receptor (85% identical), binding macrophage inflammatory protein-1α (MIP-1α) and RANTES. Mouse CCR4 transcripts are expressed in the thymus and in T-cell lines.
General Literature References
Molecular cloning of murine CC CKR-4 and high affinity binding of chemokines to murine and human CC CKR-4
:
A. Hoogewerf, et al.; BBRC
218
, 337 (1996)
Abstract
Further Categories Containing This Product:
Polyclonal Antibodies
•
CD Antibodies
ALX-210-742
Revised 31-Jul-07
Polyclonal Antibody to CCR4 (mouse)
SYNONYMS
anti-C-C Chemokine Receptor 4 (mouse) PAb
anti-CD194 (mouse) PAb
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-742-R100
100 µl
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST: