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ALX-350-359
Revised 07-Apr-08
16-epi-Latrunculin B
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Natural Products - Antiviral / anti-HIV Agents
Ordering Information
Product Numbers:
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ALX-350-359-C100
100 µg
95.00 USD
Product Specification
FORMULA:
C
20
H
29
NO
5
S
MW:
395.5
SOURCE/HOST:
Isolated from
Negombata magnifica
.
PURITY:
≥98% (HPLC)
APPEARANCE:
White to off-white powder.
SOLUBILITY:
Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml).
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Has antiviral (herpes simplex type 1) activities and cytotoxic properties.
Product Specific Literature References
Latrunculin inhibits the microfilament-mediated processes during fertilization, cleavage and early development in sea urchins and mice:
G. Schatten, et al.; Exp. Cell. Res.
166
, 191 (1986)
Abstract
Latrunculins--novel marine macrolides that disrupt microfilament organization and affect cell growth: I. Comparison with cytochalasin D:
I. Spector, et al.; Cell Motility & Cytoskeleton
13
, 127 (1989)
Abstract
Effects of cytochalasin D and latrunculin B on mechanical properties of cells:
T. Wakatsuki, et al.; J. Cell. Sci.
114
, 1025 (2001)
Abstract
Toward computing relative configurations: 16-
epi
-latrunculin B, a new stereoisomer of the actin polymerization inhibitor latrunculin B:
T.R. Hoye, et al.; JACS
124
, 7405 (2002)
Abstract
General Literature References
Latrunculin inhibits the microfilament-mediated processes during fertilization, cleavage and early development in sea urchins and mice:
G. Schatten, et al.; Exp. Cell. Res.
166
, 191 (1986)
Abstract
Inhibition of actin polymerization by latrunculin A:
M. Coué, et al.; FEBS Lett.
213
, 316 (1987)
Abstract
Latrunculin A is a potent inhibitor of phagocytosis by macrophages:
C.A. de Oliveira & B. Mantovani; Life Sci.
43
, 1825 (1988)
Abstract
Further Categories Containing This Product:
Other Toxins
•
Herpes Viruses / Related Products
•
Marine Natural Products
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