ALEXIS Biochemicals: Ras Inhibitory Peptide

Advanced Search

You are here: Product Lines > Signal Transduction > Ras Signalling Pathway > Ras / Related Products

ALX-210-022

Revised 29-Jun-05

Polyclonal Antibody to R-Ras
SYNONYMS	anti-Ras-related Protein R-Ras PAb anti-p23 PAb
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Ras / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-022-R050		50 µl	190.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse
SOURCE/HOST:	From rabbit.
FORMULATION:	Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN:	Synthetic peptide corresponding to aa 11-31 (R¹¹GRPRGGGPGPRD PPPGETHK³¹) of mouse Ras-related protein R-Ras.
SPECIFICITY:	Recognizes human and mouse R-Ras.
APPLICATION:	Immunoprecipitation Western Blot
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-80°C
USE/STABILITY:	Stable for at least 1 year after receipt when stored at -80°C.
HANDLING:	Avoid freeze/thaw cycles.

Product Specific Literature References

R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism: H.G. Wang, et al.; J. Cell. Biol. 129, 1103 (1995) Abstract; Full Text
Integrin activation by R-ras: Z. Zhang, et al.; Cell 85, 61 (1996) Abstract

General Information

MANUFACTURER

Manufactured by Apotech Corporation.

Further Categories Containing This Product:

Polyclonal Antibodies

ALX-166-001

Revised 21-Feb-03

Ras Inhibitory Peptide
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Ras / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-166-001-M001		1 mg	95.00 USD
ALX-166-001-M005		5 mg	380.00 USD

Product Specification

SEQUENCE:	H-Val-Pro-Pro-Pro-Val-Pro-Pro-Arg-Arg-Arg-OH
FORMULA:	C₅₃H₉₁N₁₉O₁₁
MW:	1170.4
PURITY:	≥97%
APPEARANCE:	White lyophilized powder.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

The peptide sequence corresponds to amino acid residues 1149-1158 of the guanine nucleotide-releasing factor hSos1, which is essential for the control of Ras activity. Blocks the binding of hSos1 to human Grb2, a protein that binds to activated receptor tyrosine kinases.

Product Specific Literature References

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling: N. Li, et al.; Nature 363, 85 (1993) Abstract

Further Categories Containing This Product:

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.