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Cell Death / Apoptosis / Autophagy
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AG-CC06H2 Revised 11-Jan-08
Clusterin (human) Competitive ELISA Kit
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SYNONYMS TRPM-2 (human) Competitive ELISA Kit
Apolipoprotein J (human) Competitive ELISA Kit
APO-J (human) Competitive ELISA Kit
CLI (human) Competitive ELISA Kit
CLU (human) Competitive ELISA Kit
SGP-2 (human) Competitive ELISA Kit
PRODUCT LINE Cell Cycle
PRODUCT CATEGORY Clusterin / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
AG-CC06H2EK-KI01   96 wells 550.00 USD Add To Cart
AG-CC06H2TP-KI01 Twin Plex 2x96 wells 890.00 USD Add To Cart
AG-CC06H2PP-KI01 Penta Plex 5x96 wells 1'870.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY: 1ng/ml
APPLICATION: For the quantitative determination of clusterin in human serum, plasma or cell culture supernatant.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
ELISA & EIA Kits
 
 
ALX-106-017 Revised 04-Mar-05
L-Pipecolic acid . hydrochloride
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SYNONYMS L-(-)-Pipecolinic acid . HCl
PRODUCT LINE Combinatorial Chemistry
PRODUCT CATEGORY Special Amino Acids
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ALX-106-017-M050   50 mg 30.00 USD Add To Cart
Product Specification
FORMULA: C6H11NO2 . HCl
MW: 129.2 . 36.5
CAS NUMBER: 3105-95-1
PURITY: ≥98%
APPEARANCE: White powder.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C

Product Description
Lysine metabolite. Defect in its catabolism is involved in hyperpipecolic acidemia, cerebro-hepato-renal syndrome, neonatal onset adrenoleukodystrophy, and infantile Refsum disease. Apoptosis inducer in neuronal cells.
Product Specific Literature References
L-pipecolic acid oxidation in the rabbit and cynomolgus monkey. Evidence for differing organellar locations and cofactor requirements in each species: S.J. Mihalik & W.J. Rhead; J. Biol. Chem. 264, 2509 (1989) Abstract; Full Text
Pipecolic acid induces apoptosis in neuronal cells: S. Matsumoto, et al.; Brain Res. 980, 179 (2003) Abstract
Further Categories Containing This Product:
Apoptosis Inducers & Inhibitors Other Products
 
 
ALX-151-026 Revised 20-Jun-08
N-Acetyl-Asp-Tyr(2-malonyl)-Val-Pro-Met-Leu-NH2
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Tyrosine Kinase Inhibitors
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ALX-151-026-M001   1 mg 90.00 USD Add To Cart
Product Specification
FORMULA: C39H57N7O14S
MW: 880.0
PURITY: ≥96% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water (1mg/ml).
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
USE/STABILITY: Peptide is very unstable.
Product Description
Peptide containing a phosphotyrosyl mimetic. Effective protein tyrosine kinase inhibitor. Inhibits the phosphoinositide 3-kinase (PI(3)K) C-terminal p85 SH2 domain.
Product Specific Literature References
L-O-(2-malonyl)tyrosine: a new phosphotyrosyl mimetic for the preparation of Src homology 2 domain inhibitory peptides: B. Ye, et al.; J. Med. Chem. 38, 4270 (1995) Abstract
Further Categories Containing This Product:
Peptides • Phosphoinositide 3-kinase [PI(3)K] / Related Products
 
 
ALX-151-027 Revised 17-Jan-05
N-Acetyl-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Tyrosine Kinase Inhibitors
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ALX-151-027-M001   1 mg 90.00 USD Add To Cart
Product Specification
FORMULA: C36H57N7O13SP
MW: 858.9
PURITY: ≥96%
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Phosphotyrosine containing peptide. Effective protein tyrosine kinase inhibitor. Inhibits the phosphoinositide 3-kinase (PI(3)K) C-terminal p85 SH2 domain.
Product Specific Literature References
L-O-(2-malonyl)tyrosine: a new phosphotyrosyl mimetic for the preparation of Src homology 2 domain inhibitory peptides: B. Ye, et al.; J. Med. Chem. 38, 4270 (1995) Abstract
Further Categories Containing This Product:
Peptides • Phosphoinositide 3-kinase [PI(3)K] / Related Products
 
 
ALX-151-031 Revised 23-Nov-06
Caspase-3 Control Peptide
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PRODUCT LINE Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY Caspase Inhibitors
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ALX-151-031-M001   1 mg 35.00 USD Add To Cart
ALX-151-031-M005   5 mg 120.00 USD Add To Cart
Product Specification
SEQUENCE: Ac-Asp-Glu-Val-Asp-OH
FORMULA: C20H30N4O12
MW: 518.5
PURITY: ≥97%
APPEARANCE: Lyophilized.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Further Categories Containing This Product:
Peptides
 
 
ALX-152-027 Revised 14-Jul-08
BimL (147-164) (human) (cell permeable)
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SYNONYMS BCL2L11 (147-164) (human) (cell permeable)
PRODUCT LINE Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY Bim / Related Products
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ALX-152-027-1   1 Vial 230.00 USD Add To Cart
Product Specification
SEQUENCE: GRKKRRQRRR-GG-WIAQELRRIGDEFNAYYA-amide
FORMULA: C161H261N61O41
MW: 3707.2
QUANTITY: 50µl
CONCENTRATION: 10mM
PURITY: ≥95% (HPLC)
FORMULATION: Liquid. In sterile PBS.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: -20°C
LONG TERM STORAGE: -80°C
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Keep on ice at all times.
POSITIVE CONTROL: Prod. No. ALX-168-009/1
Product Description
For increased cell permeability the peptide was covalently linked to the 10 aa recognized by the TAT transporter.
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Further Categories Containing This Product:
Peptides
 
 
ALX-152-028 Revised 14-Jul-08
Bax (58-75) (human) (cell permeable)
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SYNONYMS BCL2L4 (58-75) (human) (cell permeable)
PRODUCT LINE Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY Bax / Related Products
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ALX-152-028-1   1 Vial 230.00 USD Add To Cart
Product Specification
SEQUENCE: GRKKRRQRRR-GG-KLSECLKRIGDELDSNME-amide
FORMULA: C144H260N58O44S2
MW: 3572.2
QUANTITY: 50µl
CONCENTRATION: 10mM
PURITY: ≥95% (HPLC)
FORMULATION: Liquid. In sterile PBS.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: -20°C
LONG TERM STORAGE: -80°C
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Keep on ice at all times.
POSITIVE CONTROL: Prod. No. ALX-168-009/1
Product Description
For increased cell permeability the peptide was covalently linked to the 10 aa recognized by the TAT transporter.
Related Products
Further Categories Containing This Product:
Peptides
 
 
ALX-152-029 Revised 14-Jul-08
Bok (66-83) (human) (cell permeable)
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SYNONYMS NBK (66-83) (human) (cell permeable)
PRODUCT LINE Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY Bcl-2 Family Members Other Products
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ALX-152-029-1   1 Vial 230.00 USD Add To Cart
Product Specification
SEQUENCE: GRKKRRQRRR-GG-EVCTVLLRLGDELEQIRP-amide
FORMULA: C149H269N59O41S
MW: 3575.2
QUANTITY: 50µl
CONCENTRATION: 10mM
PURITY: ≥95% (HPLC)
FORMULATION: Liquid. In sterile PBS.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: -20°C
LONG TERM STORAGE: -80°C
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Keep on ice at all times.
POSITIVE CONTROL: Prod. No. ALX-168-009/1
Product Description
For increased cell permeability the peptide was covalently linked to the 10 aa recognized by the TAT transporter.
Related Products
Further Categories Containing This Product:
Peptides
 
 
ALX-153-041 Revised 04-Mar-05
Cyclin-dependent Kinase 2 Inhibitory Peptide I
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SYNONYMS CDK2/Cyclin Inhibitory Peptide I
PRODUCT LINE Cell Cycle
PRODUCT CATEGORY CDK & Cyclin Inhibitors
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ALX-153-041-C500   500 µg 145.00 USD Add To Cart
Product Specification
SEQUENCE: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Pro-Val-Lys-Arg-Arg-Leu-Phe-Gly-OH
FORMULA: C111H196N48O23
MW: 2571.1
PURITY: ≥98% (HPLC)
APPEARANCE: Solid.
FORMULATION: Lyophilized. Counter Ion: Trifluoroacetate salt.
SOLUBILITY: Soluble in water.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Following reconstitution, aliquot and freeze (-20°C). Product is stable for 2 years as supplied. Stock solutions are stable for 3 months at -20°C.
HANDLING: Hygroscopic.
Product Description
Cell permeable inhibitor of CDK2/cyclin complexes. Blocks phosphorylation of substrates by CDK2/cyclin A and CDK/cyclin E complexes. Preferentially induces apoptosis only in transformed cells and not in non-transformed cells.

Chimeric peptide consisting of the N-terminal sequence of the HIV-TAT protein (directing uptake across the cell membrane) and the consensus sequence PVKRRLFG that serves as the docking site for CDK2/cyclin complexes.
Product Specific Literature References
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists: Y.N. Chen, et al.; PNAS 96, 4325 (1999) Abstract; Full Text
Further Categories Containing This Product:
Peptides • Apoptosis Inducers & Inhibitors Other Products
 
 
ALX-153-042 Revised 04-Mar-05
Cyclin-dependent Kinase 2 Inhibitory Peptide II
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SYNONYMS CDK2/Cyclin Inhibitory Peptide II
PRODUCT LINE Cell Cycle
PRODUCT CATEGORY CDK & Cyclin Inhibitors
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ALX-153-042-C500   500 µg 145.00 USD Add To Cart
Product Specification
SEQUENCE: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Pro-Val-Lys-Arg-Arg-Leu-Asp-Leu-OH
FORMULA: C110H200N48O25
MW: 2595.1
PURITY: ≥98%
APPEARANCE: Lyophilized solid.
SOLUBILITY: Soluble in water.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Very hygroscopic.
Product Description
Cell permeable inhibitor of CDK2/cyclin complexes. Blocks phosphorylation of substrates by CDK2/cyclin A and CDK/cyclin E complexes. Preferentially induces apoptosis only in transformed cells and not in non-transformed cells.
Product Specific Literature References
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists: Y.N. Chen, et al.; PNAS 96, 4325 (1999) Abstract; Full Text
Further Categories Containing This Product:
Peptides • Apoptosis Inducers & Inhibitors Other Products
 
 
ALX-155-037 Revised 21-Oct-08
Extracellular Death Factor
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SYNONYMS EDF
PRODUCT LINE Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY Apoptosis Inducers & Inhibitors Other Products
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ALX-155-037-M001   1 mg 40.00 USD Add To Cart
ALX-155-037-M005   5 mg 120.00 USD Add To Cart
Product Specification
SEQUENCE: H-Asn-Asn-Trp-Asn-Asn-OH
FORMULA: C27H36N10O10
MW: 660.6
SOURCE/HOST: Synthetic.
PURITY: ≥97% (HPLC)
APPEARANCE: White to off-white powder.
FORMULATION: Lyophilized.
SOLUBILITY: Soluble in water or DMSO.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Programmed cell death (PCD) in E. coli depends on cell-to-cell communication, a process known as quorum sensing. The communicating cells produce and emit the extracellular death factor (EDF). After reaching a sufficent concentration, EDF activates the cell death pathway in a subset of cells.
Product Specific Literature References
A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli: I. Kolodkin-Gal, et al.; Science 318, 652 (2007) Abstract
Further Categories Containing This Product:
Peptides
 
 
ALX-158-011 Revised 12-Sep-05
Humanin (human)
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PRODUCT LINE Neurobiology
PRODUCT CATEGORY Alzheimer Research Other Products
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