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Items 18 of 18
ALX-210-715
Revised 14-Jul-08
Polyclonal Antibody to PAF Receptor
SYNONYMS
anti-Platelet Activating Factor Receptor PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
Platelet Activating Factors [PAF] & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-210-715-1
1 Vial
269.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Pig
SOURCE/HOST:
From rabbit.
CONCENTRATION:
PURITY DETAIL:
Affinity purified antibody.
FORMULATION:
Liquid. In 500µl TBS, pH 7.4, containing 0.5mg/ml BSA, 50% glycerol and 0.02% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 1-17 (M
1
EPHDSSHMDSEF
RYTL
17
) of human PAF receptor (platelet activating factor receptor).
SPECIFICITY:
Recognizes human, mouse, rat and pig PAF receptor.
APPLICATION:
Flow Cytometry
Immunocytochemistry
Western Blot (1:200)
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-165-057
.
General Literature References
Platelet-activating factor mediates CD40-dependent angiogenesis and endothelial-smooth muscle cell interaction
:
S. Russo, et al.; J. Immunol.
171
, 5489 (2003)
Abstract
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-765
Revised 07-Aug-08
Polyclonal Antibody to PAF Acetylhydrolase (human)
SYNONYMS
anti-Platelet Activating Factor Acetylhydrolase (human) PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
Platelet Activating Factors [PAF] & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-765-1
1 Vial
269.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
CONCENTRATION:
0.6mg/ml
FORMULATION:
Liquid. In 500μl TBS, pH 7.4, containing 50% glycerol, 0.5mg/ml BSA and 0.02% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 420-441 (T
420
NINTTNQHI
MLQNSSGIEKYN
441
) of C-terminal human plasma PAF-acetylhydrolase.
SPECIFICITY:
Recognizes human plasma PAF-acetylhydrolase. Detects a band of ~45kDa by Western blot. Does not cross-react with mouse, guinea pig, dog or chicken PAF-acetylhydrolase.
APPLICATION:
Western Blot (1:200)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
General Information
PAF-acetylhydrolase (PAF-AH) catalyzes the hydrolysis of the acetyl group at the
sn
-2 position of PAF to yield lyso-PAF and acetate, thereby inactivating PAF. Two main types of PAF-AH have been characterized, namely secreted (i.e. plasma) and intracellular enzymes, which are encoded on individual genes and share only 41% homology at the amino acid level [1-3]. Plasma PAF-AH is a 45kDa enzyme which is associated with the LDL fraction of plasma [2,4].
General Literature References
[1]
Platelet-activating factor acetylhydrolases :
D.M. Stafforini, et al.; J. Biol. Chem.
272
, 17895 (1997)
Abstract
;
Full Text
[2]
Anti-inflammatory properties of a platelet-activating factor acetylhydrolase:
L.W. Tjoelker, et al.; Nature
374
, 549 (1995)
Abstract
[3]
cDNA cloning and expression of intracellular platelet-activating factor (PAF) acetylhydrolase II. Its homology with plasma PAF acetylhydrolase:
K. Hattori, et al.; J. Biol. Chem.
271
, 33032 (1996)
Abstract
;
Full Text
[4]
Human plasma platelet-activating factor acetylhydrolase. Purification and properties:
D.M. Stafforini; J. Biol. Chem.
262
, 4223 (1987)
Abstract
;
Full Text
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-301-001
Revised 09-Dec-04
PAF (C16)
SYNONYMS
1-O-Hexadecyl-2-acetyl-
sn
-glycero-3-phosphocholine
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
Platelet Activating Factors [PAF] & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-301-001-M001
1 mg
15.00 USD
ALX-301-001-M005
5 mg
40.00 USD
ALX-301-001-M025
25 mg
145.00 USD
ALX-301-001-M100
100 mg
300.00 USD
Product Specification
FORMULA:
C
26
H
54
NO
7
P
MW:
523.7
CAS NUMBER:
74389-68-7
MERCK INDEX:
14:
7524
SOURCE/HOST:
Synthetic.
PURITY:
≥99%
SOLUBILITY:
Soluble in chloroform, methanol or 100% ethanol. Soluble in water after sonification for 1 minute at 40°C.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Further Categories Containing This Product:
Phospholipids / Related Products
ALX-301-002
Revised 09-Dec-04
Lyso-PAF (C16)
SYNONYMS
1-O-Hexadecyl-
sn
-glycero-3-phosphocholine
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
Platelet Activating Factors [PAF] & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-301-002-M001
1 mg
15.00 USD
ALX-301-002-M005
5 mg
45.00 USD
ALX-301-002-M025
25 mg
135.00 USD
ALX-301-002-M100
100 mg
280.00 USD
Product Specification
FORMULA:
C
24
H
52
NO
6
P
MW:
481.7
CAS NUMBER:
52691-62-0
SOURCE/HOST:
Synthetic.
PURITY:
≥98%
SOLUBILITY:
Soluble in chloroform, methanol or ethanol. Soluble in water after sonification for 1 minute at 40°C.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Slightly hygroscopic.
Further Categories Containing This Product:
Phospholipids / Related Products
ALX-301-003
Revised 09-Dec-04
PAF (C18)
SYNONYMS
1-O-Octadecyl-2-acetyl-
sn
-glycero-3-phosphocholine
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
Platelet Activating Factors [PAF] & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-301-003-M001
1 mg
15.00 USD
ALX-301-003-M005
5 mg
40.00 USD
ALX-301-003-M025
25 mg
145.00 USD
ALX-301-003-M100
100 mg
300.00 USD
Product Specification
FORMULA:
C
28
H
58
NO
7
P
MW:
551.8
CAS NUMBER:
79549-26-1
MERCK INDEX:
14:
7524
SOURCE/HOST:
Synthetic.
PURITY:
≥99%
SOLUBILITY:
Soluble in chloroform, methanol or 100% ethanol. Soluble in water after sonification for 1 minute at 40°C.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Further Categories Containing This Product:
Phospholipids / Related Products
ALX-301-004
Revised 09-Dec-04
Lyso-PAF (C18)
SYNONYMS
1-O-Octadecyl-
sn
-glycero-3-phosphocholine
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
Platelet Activating Factors [PAF] & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-301-004-M001
1 mg
15.00 USD
ALX-301-004-M005
5 mg
45.00 USD
ALX-301-004-M025
25 mg
135.00 USD
Product Specification
FORMULA:
C
26
H
56
NO
6
P
MW:
509.7
CAS NUMBER:
74430-89-0
SOURCE/HOST:
Sythetic.
PURITY:
≥98%
SOLUBILITY:
Soluble in chloroform, methanol or 100% ethanol. Soluble in water after sonification for 1 minute at 40°C.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Slightly hygroscopic.
Further Categories Containing This Product:
Phospholipids / Related Products
ALX-301-005
Revised 09-Dec-04
PAF (C16), Enantio-
SYNONYMS
3-O-Hexadecyl-2-acetyl-
sn
-glycero-1-phosphocholine
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
Platelet Activating Factors [PAF] & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-301-005-M001
1 mg
15.00 USD
ALX-301-005-M005
5 mg
45.00 USD
ALX-301-005-M025
25 mg
135.00 USD
Product Specification
FORMULA:
C
26
H
54
NO
7
P
MW:
523.7
CAS NUMBER:
117985-57-6
SOURCE/HOST:
Synthetic.
PURITY:
≥99%
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Further Categories Containing This Product:
Phospholipids / Related Products
ALX-301-007
Revised 09-Dec-04
PAF (C16), Propionyl-
SYNONYMS
1-O-Hexadecyl-2-propionyl-
sn
-glycero-3-phosphocholine
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
Platelet Activating Factors [PAF] & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-301-007-M001
1 mg
30.00 USD
ALX-301-007-M005
5 mg
90.00 USD
ALX-301-007-M025
25 mg
270.00 USD
Product Specification
FORMULA:
C
27
H
56
NO
7
P
MW:
537.7
SOURCE/HOST:
Synthetic.
PURITY:
≥98%
APPEARANCE:
Lyophilized solid.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Slightly hygroscopic.
Product Description
2-fold more potent analog than PAF.
Further Categories Containing This Product:
Phospholipids / Related Products
ALX-301-008
Revised 09-Dec-04
PAF (C18), Propionyl-
SYNONYMS
1-O-Octadecyl-2-propionyl-
sn
-glycero-3-phosphocholine
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
Platelet Activating Factors [PAF] & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-301-008-M001
1 mg
30.00 USD
ALX-301-008-M005
5 mg
90.00 USD
ALX-301-008-M025
25 mg
270.00 USD
Product Specification
FORMULA:
C
29
H
60
NO
7
P
MW:
565.8
SOURCE/HOST:
Synthetic.
PURITY:
≥98%
APPEARANCE:
Lyophilized solid.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
2-fold more potent analog than PAF.
Further Categories Containing This Product:
Phospholipids / Related Products
ALX-301-009
Revised 09-Dec-04
1-O-Hexadecyl-2-acetyl-sn-glycero-3-phospho-(N,N,N-trimethyl)-hexanolamine
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
Platelet Activating Factors [PAF] & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-301-009-M005
5 mg
45.00 USD
ALX-301-009-M025
25 mg
180.00 USD
Product Specification
FORMULA:
C
30
H
62
NO
7
P
MW:
579.8
CAS NUMBER:
99103-16-9
PURITY:
≥98%
APPEARANCE:
White solid.
SOLUBILITY:
Soluble in chloroform, 100% ethanol or methanol. Soluble in water after sonification for 1 minute at 40°C.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Slightly hygroscopic.
Product Description
PAF antagonist. Shows inhibitory behavior on platelet aggregation, secretion and phospholipid turnover.
Product Specific Literature References
Structural analogs of alkylacetylglycerophosphocholine inhibitory behavior on platelet activation:
A. Tokumura, et al.; J. Biol. Chem.
260
, 12710 (1985)
Abstract
;
Full Text
Platelet activating factor is a potent stimulant of the production of active oxygen species by human monocyte-derived macrophages:
M. Rouis, et al.; BBRC
156
, 1293 (1988)
Abstract
Further Categories Containing This Product:
Phospholipids / Related Products
•
Antithrombotic Agents / Platelet Aggregation Inhibitors / Related Products
ALX-301-010
Revised 18-Feb-08
PAF (C16), Carbamyl-
SYNONYMS
1-O-Hexadecyl-2-N-methylcarbamyl-
sn
-glycero-3-phosphocholine
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
Platelet Activating Factors [PAF] & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-301-010-M001
1 mg
35.00 USD
ALX-301-010-M005
5 mg
140.00 USD
Product Specification
FORMULA:
C
26
H
55
N
2
O
7
P
MW:
538.7
CAS NUMBER:
91575-58-5
SOURCE/HOST:
Synthetic.
PURITY:
≥98%
APPEARANCE:
White to off-white solid.
SOLUBILITY:
Soluble in 100% ethanol, acetone, DMSO or acetonitrile purged with an inert gas.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Very hygroscopic.
