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ELISA & EIA Kits
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ALX-850-286 Revised 28-Sep-06
Phospho-IκBα ActivELISA™ Assay Kit
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inhibitors of kappa B [IkB] / Related Products
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ALX-850-286-KI01   1 Kit 559.00 USD Add To Cart
Product Specification
QUANTITY: 2x96 wells.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Description
ELISA based assay for the detection and analysis of IκBα-phosphorylation. Phosphorylation of IκBα is correlated with the activity of the IKK complex as well as the nuclear localization and activation of NF-κB.
General Information
MANUFACTURER Manufactured by Imgenex.
Further Categories Containing This Product:
ELISA & EIA Kits
 
 
ALX-850-292 Revised 25-Sep-08
Cystatin C (human) ELISA Kit
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Cystatins / Related Products
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ALX-850-292-KI01   1 Kit 461.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY: 0.2ng/ml (range 200 to 10’000ng/ml)
QUANTITY: For 96 wells (~80 tests)
APPLICATION: For the quantitative determination of human cystatin C in serum, plasma, cell culture supernatant and other body fluids. Weakly cross-reacts with cat and dog cystatin C. Does not cross-react with mouse and rat sera.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Specific Literature References
Cathepsin S, a novel biomarker of adiposity: relevance to atherogenesis: S. Taleb, et al.; FASEB J. 19, 1540 (2005) Abstract; Full Text
Weight loss reduces adipose tissue cathepsin S and its circulating levels in morbidly obese women: S. Taleb, et al.; J. Clin. Endocrinol. Metab. 91, 1042 (2006) Abstract; Full Text
General Information
MANUFACTURER Manufactured by BioVendor.
Further Categories Containing This Product:
ELISA & EIA Kits
 
 
ALX-850-296 Revised 26-Sep-08
Leptin Receptor (human) ELISA Kit
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SYNONYMS OB-R (human) ELISA Kit
CD295 (human) ELISA Kit
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Leptin / Related Products
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ALX-850-296-KI01   1 Kit 696.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY: 0.4ng/ml (range 2 to 100ng/ml)
QUANTITY: For 96 wells (~80 tests)
APPLICATION: For the quantitative determination of human leptin receptor in serum, plasma and cell culture supernatant. Weakly cross-reacts with mouse, dog, horse and pig leptin receptor. Does not cross-react with rat serum.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
USE/STABILITY: Stable for at least 6 months when stored at +4°C.
Product Specific Literature References
Regulation of circulating soluble leptin receptor levels by gender, adiposity, sex steroids, and leptin: observational and interventional studies in humans: J.L. Chan, et al.; Diabetes 51, 2105 (2002) Abstract
Mutations in the human leptin and leptin receptor genes as models of serum leptin receptor regulation: N. Lahlou, et al.; Diabetes 51, 1980 (2002) Abstract
Weight loss increases soluble leptin receptor levels and the soluble receptor bound fraction of leptin: M. Laimer, et al.; Obes. Res. 10, 597 (2002) Abstract
Soluble leptin receptor and insulin resistance as determinant of sleep apnea: D. Manzella, et al.; Int. J. Obes. Relat. Metab. Disord. 26, 370 (2002) Abstract
Opposite modifications in circulating leptin and soluble leptin receptor across the eating disorder spectrum: P. Monteleone, et al.; Mol. Psychiatry 7, 641 (2002) Abstract
Obesity is associated with decreasing levels of the circulating soluble leptin receptor in humans: V. Ogier, et al.; Int. J. Obes. Relat. Metab. Disord. 26, 496 (2002) Abstract
Soluble leptin receptors and serum leptin in end-stage renal disease: relationship with inflammation and body composition: R. Pecoits-Filho, et al.; Eur. J. Clin. Invest. 32, 811 (2002) Abstract
Circulating concentrations of soluble leptin receptor: influence of menstrual cycle and diet therapy: H. Shimizu, et al.; Nutrition 18, 309 (2002) Abstract
Leptin and soluble leptin receptor levels in obese and weight-losing individuals: F.M. van Dielen, et al.; J. Clin. Endocrinol. Metab. 87, 1708 (2002) Abstract
Leptin, soluble leptin receptor, and transforming growth factor-beta1 levels in minimal change nephrotic syndrom: N. Buyan, et al.; Pediatr. Nephrol. 18, 1009 (2003) Abstract
Diurnal and ultradian dynamics of serum adiponectin in healthy men: comparison with leptin, circulating soluble leptin receptor, and cortisol patterns: A. Gavrila, et al.; J. Clin. Endocrinol. Metab. 88, 2838 (2002) Abstract; Full Text
Relationships between the serum levels of soluble leptin receptor and free and bound leptin in non-pregnant women of reproductive age and women undergoing controlled ovarian hyperstimulation: N. Kado, et al.; Hum. Reprod. 18, 715 (2003) Abstract; Full Text
Changes in circulating leptin, leptin receptor, and gonadal hormones from infancy until advanced age in humans: D.R. Mann, et al.; J. Clin. Endocrinol. Metab. 88, 3339 (2003) Abstract; Full Text
Serum ghrelin levels in obese patients: the relationship to serum leptin levels and soluble leptin receptors levels: M. Rosicka, et al.; Physiol. Res. 52, 61 (2003) Abstract; Full Text
Soluble leptin receptor and soluble receptor-bound fraction of leptin in the metabolic syndrome: A. Sandhofer, et al.; Obes. Res. 11, 760 (2003) Abstract; Full Text
Body fat mass and macronutrient intake in relation to circulating soluble leptin receptor, free leptin index, adiponectin, and resistin concentrations in healthy humans: M. Yannakoulia, et al.; J. Clin. Endocrinol. Metab. 88, 1730 (2003) Abstract; Full Text
Leptin and its soluble receptor in plasma of patients suffering from remitting-relapsing multiple sclerosis (MS) In vitro effects of leptin on type-1 and type-2 cytokine secretion by peripheral blood mononuclear cells, T-cells and monocytes of MS patients: K. Chatzantoni, et al.; J. Autoimm. 23, 169 (2004) Abstract
Hormonal and body composition predictors of soluble leptin receptor, leptin, and free leptin index in adolescent girls with anorexia nervosa and controls and relation to insulin sensitivity: M. Misra, et al.; J. Clin. Endocrinol. Metab. 89, 3486 (2004) Abstract; Full Text
Serum leptin, soluble leptin receptor, free leptin index and bone mineral density in patients with primary biliary cirrhosis: F. Szalay, et al.; Eur. J. Gastroenterol. Hepatol. 17, 923 (2005) Abstract
Expression of leptin receptors in mononuclear cells from myelodysplastic syndromes and acute myeloid leukemias: P.C. Tsiotra, et al.; Acta Haematol. 114, 71 (2005) Abstract
General Information
MANUFACTURER Manufactured by BioVendor.
General Literature References
Identification and expression cloning of a leptin receptor: L.A. Tartaglia, et al.; Cell 83, 1263 (1995) Abstract
Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice: H. Chen, et al.; Cell 84, 491 (1996) Abstract
Novel B219/OB receptor isoforms: possible role of leptin in hematopoiesis and reproduction: J.A. Cioffi, et al.; Nat. Med. 2, 585 (1996) Abstract
Abnormal splicing of the leptin receptor in diabetic mice: G.H. Lee; Nature 379, 632 (1996) Abstract
The leptin receptor: L.A. Tartaglia; J. Biol. Chem. 272, 6093 (1997) Abstract
Leptin: J. Auwerx & B. Staels; Lancet 351, 737 (1998), (Review) Abstract
Leptin and its receptors: regulators of whole-body energy homeostasis: K.L. Houseknecht & C.P. Portocarrero; Domest. Anim. Endocrinol. 15, 457 (1998) Abstract
Further Categories Containing This Product:
CD Kits & SetsELISA & EIA Kits
 
 
ALX-850-297 Revised 26-Sep-08
Resistin (human) ELISA Kit
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SYNONYMS ADSF (human) ELISA Kit
FIZZ3 (human) ELISA Kit
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Resistin & Resistin-like Molecules [RELMs] / Related Products
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ALX-850-297-KI01   1 Kit 618.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Monkey
Others
SENSITIVITY: 0.033ng/ml (range 1 to 50 ng/ml)
QUANTITY: For 96 wells (~80 tests)
APPLICATION: For the quantitative determination of human resistin in serum, plasma and cell culture supernatant. Cross-reacts strongly with monkey and horse and weakly with pig resistin. Does not cross-react with mouse and rat sera.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Specific Literature References
Common genetic polymorphisms in the promoter of resistin gene are major determinants of plasma resistin concentrations in humans: Y.M. Cho, et al.; Diabetologia 47, 559 (2004) Abstract
Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus: B.S. Youn, et al.; J. Clin. Endocrinol. Metab. 89, 150 (2004) Abstract
Effects of retinoid therapy on insulin sensitivity, lipid profile and circulating adipocytokines: S. Corbetta, et al.; Eur. J. Endocrinol. 154, 83 (2006) Abstract; Full Text
General Information
MANUFACTURER Manufactured by BioVendor.
Further Categories Containing This Product:
ELISA & EIA Kits
 
 
ALX-850-298 Revised 11-Apr-08
VEGF-A (human) BioLISA Kit
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SYNONYMS Vascular Endothelial Growth Factor A (human) BioLISA Kit
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY VEGFs
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ALX-850-298-KI01   1 Kit 682.00 USD Add To Cart
Product Specification
SENSITIVITY: 7.26pg/ml (range 15.6 to 1000pg/ml)
QUANTITY: 96 wells (~80 tests).
APPLICATION: For the quantitative determination of active human VEGF-A in cell culture supernatant, serum, plasma and other body fluids.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Description
Compared to normal ELISA kits, this kit uses rsVEGFR-1 to capture the antigen instead of an antibody, thus only biologically active VEGF-A will be measured.
Product Specific Literature References
Anti-angiogenic effect of silymarin on colon cancer LoVo cell line: S.H. Yang, et al.; J. Surg. Res. 113, 133 (2003) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link P15692: VEGF-A (human) (precursor)
MANUFACTURER Manufactured by Bender MedSystems.
Further Categories Containing This Product:
ELISA & EIA Kits
 
 
ALX-850-300 Revised 25-Sep-08
TRAP5 (human) ImmunoCapture Enzyme-Activity Assay Kit
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY TRAP5 [TRACP]
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ALX-850-300-KI01   1 Kit 852.00 USD Add To Cart
Product Specification
SENSITIVITY: 0.4U/l (range 0.2 to 4U/l)
QUANTITY: 96 wells (~80 tests)
APPLICATION: For the quantitative determination of human TRAP5 in serum and plasma. The kit measures only the TRAP5 proteins exhibiting enzymatic activity. Weakly cross-reacts with dog, monkey and rabbit TRAP5. Does not cross-react with mouse and rat sera.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
TRAP5b is claimed to be a specific marker of bone resorption [2-4]. Both osteopontin and bone sialoprotein are colocalized with TRAP5 in the resorption lacuna of osteoclasts and dephosphorylation of osteopontin impair its ability to promote adhesion as well as migration of osteoclasts in vitro [5].
MANUFACTURER Manufactured by BioVendor.
General Literature References
[1] Purification and N-terminal sequence of two tartrate-resistant acid phosphatases type-5 from the hairy cell leukemia spleen: J.J. Stepan, et al.; BBRC 165, 1027 (1989) Abstract
[2] Tartrate-resistant acid phosphatase 5b: a novel serum marker of bone resorption: J.M. Halleen, et al.; J. Bone Miner. Res 15, 1337 (2000) Abstract
[3] Tartrate-resistant acid phosphatase isoform 5b as serum marker for osteoclastic activity: A.J. Janckila, et al.; Clin. Chem. 47, 74 (2001) Abstract
[4] Clinical performance of immunoreactive tartrate-resistant acid phosphatase isoform 5b as a marker of bone resorption: R.A. Hannon, et al.; Bone 34, 187 (2001) Abstract
[5] TRACP as an osteopontin phosphatase: G. Andersson, et al.; J. Bone Miner. Res 18, 1912 (2003) Abstract
Further Categories Containing This Product:
ELISA & EIA Kits
 
 
ALX-850-306 Revised 14-Apr-08
VEGF-C (human) ELISA Kit
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SYNONYMS Vascular Endothelial Growth Factor C (human) ELISA Kit
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY VEGFs
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ALX-850-306-KI01   1 Kit 619.00 USD Add To Cart
Product Specification
SENSITIVITY: 12.8pg/ml (range 46.9 to 3000pg/ml)
QUANTITY: 96 wells (~80 tests).
APPLICATION: For the quantitative determination of active human VEGF-C (vascular endothelial growth factor C) in cell culture supernatants, serum and other body fluids.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
MANUFACTURER Manufactured by Bender MedSystems.
Further Categories Containing This Product:
ELISA & EIA Kits
 
 
ALX-850-309 Revised 06-Oct-08
sHLA-G ELISA Kit
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PRODUCT LINE Immunology
PRODUCT CATEGORY MHC Proteins & Human Leukocyte Antigens [HLA] / Related Products
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ALX-850-309-KI01   1 Kit 1'431.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Goat
Sheep
Dog
Monkey
SENSITIVITY: 1U/ml (range 1.95 to 125U/ml)
QUANTITY: For 96 wells (~80 tests)
APPLICATION: For the quantitative determination of soluble human HLA-G (leukocyte antigen-G) in plasma, serum, cell culture supernatant and other body fluids. Cross-reacts strongly with bovine, dog, goat, monkey, rabbit and sheep HLA-G. Cross-reacts weakly with cat HLA-G.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
MANUFACTURER Manufactured by Exbio/BioVendor.
Further Categories Containing This Product:
ELISA & EIA Kits
 
 
ALX-850-310 Revised 04-Jul-08
M65® ELISA Kit
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PRODUCT LINE Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY Cytokeratin-based Apoptosis Detection
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ALX-850-310-KI01 (CE Mark) 1 Kit Inquire
Product Specification
APPLICATION: For the specific and sensitive detection of soluble CK18 (cytokeratin 18). The M65® ELISA is primarily intended for quantitative determination of total cell death (apoptosis and necrosis) of CK18-positive cells (e.g. carcinoma) in human serum and plasma samples.
Use in combination with the M30-Apoptosense® ELISA Kit (Prod. No. ALX-850-270) to allow the calculation of apoptosis:necrosis ratios.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HANDLING: Do not freeze.
Product Specific Literature References
Differentiation between cell death modes using measurements of different soluble forms of extracellular cytokeratin 18: G. Kramer, et al.; Cancer Res. 64, 1751 (2004) Abstract
Determining tumor apoptosis and necrosis in patient serum using cytokeratin 18 as a biomarker: S. Linder, et al.; Cancer Lett. 214, 1 (2004) Abstract
Apoptosis pathway-targeted drugs--from the bench to the clinic: J. Cummings, et al; Biochim. Biophys. Acta 1705, 53 (2004) Abstract
Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis: H. Erdal, et al.; PNAS 102, 192 (2005) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION Please also see our Product Flyer "M30 CytoDEATH™ - Key Marker to Detect Apoptosis in Epithelial Cells" (click here to download pdf) and the Original Manufacturer’s Product Description.
MANUFACTURER Manufactured by Peviva AB.
Further Categories Containing This Product:
ELISA & EIA KitsTumor Markers
 
 
ALX-850-311 Revised 14-Apr-08
CD40L, Soluble (human) ELISA Kit (high sensitivity)
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SYNONYMS CD154, Soluble (human) ELISA Kit (high sensitivity)
TNFSF 5, Soluble (human) ELISA Kit (high sensitivity)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY CD40 & CD40L [CD154] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-850-311-KI01   1 Kit 682.00 USD Add To Cart
Product Specification
SENSITIVITY: 0.005ng/ml (range 0.08 to 5ng/ml)
QUANTITY: 96 wells (~80 tests).
APPLICATION: For the quantitative determination of soluble human CD40L (CD154) in cell culture supernatants, serum and other body fluids.
SHIPPING: SHIPPED ON BLUE ICE
HANDLING: Store controls at -20°C. Store rest of the kit at +4°C.
Product Specific Literature References
CD40-ligand stimulates myelopoiesis by regulating flt3-ligand and thrombopoietin production in bone marrow stromal cells: A. Solanilla, et al.; Blood 95, 3758 (2000) Abstract
Levels of soluble CD40 ligand (CD154) in serum are increased in human immunodeficiency virus type 1-infected patients and correlate with CD4(+) T-cell counts: N.V. Sipsas, et al.; Clin. Diagn. Lab. Immunol. 9, 558 (2002) Abstract
Increased soluble and platelet-associated CD40 ligand in essential thrombocythemia and reactive thrombocytosis: J.F. Viallard, et al.; Blood 99, 2612 (2002) Abstract
Measurement of soluble P-selectin and soluble CD40 ligand in serum and plasma: J. Thom, et al.; J. Thromb. Haemost. 2, 2067 (2004) Abstract
Soluble CD40 ligand in acute and chronic heart failure: T. Ueland, et al.; Eur. Heart. J. 26, 1101 (2005) Abstract
Increased levels of soluble CD40L in African tick bite fever: possible involvement of TLRs in the pathogenic interaction between Rickettsia africae, endothelial cells, and platelets: J.K. Damas, et al.; J. Immunol. 177, 2699 (2006) Abstract
General Information
MANUFACTURER Manufactured by Bender MedSystems.
Further Categories Containing This Product:
CD Kits & Sets