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ALX-210-414
Revised 03-Oct-05
Polyclonal Antibody to CD137 (human)
SYNONYMS
anti-4-1BB (human) PAb
anti-TNFRSF 9 (human) PAb
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CD137 & CD137L / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-414-C100
100 µg
290.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN:
Human CD137.
SPECIFICITY:
Recognizes human CD137. Detects a band of ~29kDa by Western blot. Does not cross-react with mouse CD137.
APPLICATION:
Flow Cytometry (1:500-1:1'000)
Western Blot (1:2'000-1:5'000)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Polyclonal Antibodies
•
CD Antibodies
ALX-210-825
Revised 08-Dec-04
Polyclonal Antibody to CD137 (mouse)
SYNONYMS
anti-4-1BB (mouse) PAb
anti-TNFRSF 9 (mouse) PAb
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CD137 & CD137L / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-825-C100
100 µg
280.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST:
From rabbit.
CONCENTRATION:
0.9mg/ml
FORMULATION:
Liquid. 100µg of purified antibody in PBS containing 0.02% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 243-256 (C
243
PQEEEGGGGGYEL
256
) of the C-terminal cytoplasmic domain of mouse CD137 (4-1BB).
SPECIFICITY:
Recognizes mouse CD137.
APPLICATION:
Immunoprecipitation
Western Blot (recommended starting dilution: 1µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Cloning and expression of murine CD27: comparison with 4-1BB, another lymphocyte-specific member of the nerve growth factor receptor family:
L.A. Gravestein, et al.; Eur. J. Immunol.
23
, 943 (1993)
Abstract
Further Categories Containing This Product:
Polyclonal Antibodies
•
CD Antibodies
ALX-215-015
Revised 29-Nov-06
Polyclonal Antibody to IRAK-4
SYNONYMS
anti-Interleukin-1 Receptor Associated Kinase 4 PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
IL-1 Receptor-associated Kinases [IRAKs] / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-215-015-C100
100 µg
267.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST:
From rabbit.
CONCENTRATION:
0.5mg/ml
PURITY DETAIL:
Protein G-affinity purified.
FORMULATION:
Liquid. In PBS containing 0.2% gelatin and 0.05% sodium azide.
IMMUNOGEN:
Mixture of synthetic peptides corresponding aa 38-54 (A
38
IKKPSGDDRYNQFHIR
54
) and aa 120-136 (V
120
AQTHGPCQEKDRTSVM
136
) of mouse IRAK-4.
SPECIFICITY:
Recognizes human and mouse IRAK-4.
APPLICATION:
Western Blot (1:500-1:1'000)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for 6 months when stored at +4°C.
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B:
K. Asehnoune, et al.; J. Immunol.
172
, 2522 (2004)
Abstract
;
Full Text
Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein:
F. Hatao, et al.; J. Leukoc. Biol.
76
, 904 (2004)
Abstract
;
Full Text
Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1:
K.C. Choi, et al.; Nat. Immunol.
7
, 1057 (2006)
Abstract
Further Categories Containing This Product:
Polyclonal Antibodies
•
CD Antibodies
ALX-210-230
Revised 10-Oct-06
Polyclonal Antibody to Nerve Growth Factor Receptor
SYNONYMS
anti-NGFR PAb
anti-TNFRSF 16 PAb
anti-p75
NTR
PAb
anti-p75 Neurotrophin Receptor PAb
anti-CD271 PAb
anti-Low-affinity Nerve Growth Factor Receptor PAb
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
Nerve Growth Factors [NGF] & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-230-R100
100 µl
280.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Rat
Others
SOURCE/HOST:
From rabbit.
FORMULATION:
Liquid. Antiserum containing 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to a portion of C-terminal human NGFR (nerve growth factor receptor; p75
NTR
).
SPECIFICITY:
Recognizes human, rat and chicken NGFR.
APPLICATION:
Immunoprecipitation (2µl/sample)
Western Blot (1:250-1:500)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
Further Categories Containing This Product:
Polyclonal Antibodies
•
CD Antibodies
ALX-210-921
Revised 31-Oct-06
Polyclonal Antibody to Nerve Growth Factor Receptor (human) (AT101)
SYNONYMS
anti-NGFR (human) PAb (AT101)
anti-TNFRSF 16 (human) PAb (AT101)
anti-p75
NTR
(human) PAb (AT101)
anti-p75 Neurotrophin Receptor (human) PAb (AT101)
anti-CD271 (human) PAb (AT101)
anti-Low-affinity Nerve Growth Factor Receptor (human) PAb (AT101)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
Nerve Growth Factors [NGF] & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-210-921-C050
50 µg
180.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml
PURITY DETAIL:
Epitope-affinity purified.
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide
IMMUNOGEN:
Recombinant human NGFR (nerve growth factor receptor; p75
NTR
) (Prod. No.
ALX-522-044
).
SPECIFICITY:
Recognizes human NGFR.
APPLICATION:
Western Blot (1:1’000)
Note:
Does not work for Immunoprecipitation.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored at -20°C.
HANDLING:
Avoid freeze/thaw cycles.
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
General Literature References
An autocrine function of nerve growth factor for cell cycle regulation of vascular endothelial cells:
A. Tanaka, et al.; BBRC
313
, 1009 (2004)
Abstract
p75NTR--live or let die:
A. Nykjaer, et al.; Curr. Opin. Neurobiol.
15
, 49 (2005)
Abstract
Further Categories Containing This Product:
Neurotensin / Related Products
•
Polyclonal Antibodies
•
CD Antibodies
ALX-210-200
Revised 22-Feb-05
Polyclonal Antibody to Prion Protein (sheep)
SYNONYMS
anti-PrP (sheep) PAb
anti-CD230 (sheep) PAb
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
Prion Protein / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
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ALX-210-200-R100
100 µl
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Sheep
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. Epitope affinity purified IgG in PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 90-102 (G
90
QGGGTHNQWNKP
102
) of hamster PrP (prion protein).
SPECIFICITY:
Recognizes sheep PrPC 33-35 and PrPSc 27-30.
APPLICATION:
Immunohistochemistry (formalin-fixed sections (1:20))
Western Blot (1:1'000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-165-035
.
Product Specific Literature References
Characterization of prion proteins with monospecific antisera to synthetic peptides:
R.A. Barry, et al.; J. Immunol.
140
, 1188 (1988)
Abstract
Related Products
ALX-165-035
Blocking Peptide for PAb to Prion Protein (sheep) (Prod. No.
ALX-210-200
)
Further Categories Containing This Product:
Polyclonal Antibodies
•
CD Antibodies
ALX-210-421
Revised 30-Oct-06
Polyclonal Antibody to RANK (ectodomain) (human)
SYNONYMS
anti-TRANCE-R (ectodomain) (human) PAb
anti-ODFR (ectodomain) (human) PAb
anti-TNFRSF 11A (ectodomain) (human) PAb
anti-CD265 (ectodomain) (human) PAb
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
RANK & RANKL
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-421-C050
50 µg
195.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml.
FORMULATION:
Liquid. Contains no preservatives.
IMMUNOGEN:
Recombinant human RANK.
SPECIFICITY:
Recognizes human RANK. Detects a band of ~24kDa by Western blot.
APPLICATION:
Flow Cytometry
Western blot
(1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Polyclonal Antibodies
•
CD Antibodies
ALX-210-396
Revised 27-Mar-08
Polyclonal Antibody to RANKL (human)
SYNONYMS
anti-ODF (human) PAb
anti-OPGL (human) PAb
anti-TRANCE (human) PAb
anti-TNFSF 11 (human) PAb
anti-CD254 (human) PAb
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
RANK & RANKL
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-396-C100
100 µg
290.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml.
PURITY DETAIL:
Purified IgG.
FORMULATION:
Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN:
Recombinant human RANKL.
SPECIFICITY:
Recognizes human RANKL. Detects a band of ~35kDa band by Western blot.
APPLICATION:
ELISA
(direct and indirect: 1:2'000-1:10'000).
Flow Cytometry
(1:500-1:1'000).
Western Blot
(1:2'000-1:5'000 using ECL).
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Polyclonal Antibodies
•
CD Antibodies
ALX-210-800
Revised 27-Nov-08
Polyclonal Antibody to TACI
SYNONYMS
anti-Transmembrane Activator and CAML Interactor PAb
anti-TNFRSF 13B PAb
anti-CD267 PAb
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
TACI
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
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ALX-210-800-C100
100 µg
293.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST:
From rabbit.
CONCENTRATION:
0.5mg/ml
PURITY DETAIL:
Protein G-affinity purified.
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 116-132 of human TACI (transmembrane activator and CAML interactor). This sequence is 65% conserved in mouse TACI.
SPECIFICITY:
Recognizes human and mouse TACI. Detects a band of ~32kDa by Western blot.
APPLICATION:
Western Blot (0.1-0.5µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for 6 months when stored at +4°C.
HANDLING:
Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
POSITIVE CONTROL:
Human spleen, Daudi or RAW cells are recommended as positive control.
Product Images
Please click on thumbnails to enlarge.
Further Categories Containing This Product:
Polyclonal Antibodies
•
CD Antibodies
ALX-215-011
Revised 30-Oct-07
Polyclonal Antibody to Toll-like Receptor 1
SYNONYMS
anti-TLR1 PAb
anti-CD281 PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
TLR Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-215-011-C100
100 µg
293.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Rat
SOURCE/HOST:
From rabbit.
CONCENTRATION:
0.5mg/ml
PURITY DETAIL:
Protein G-affinity purified.
FORMULATION:
Liquid. In PBS containing 0.2% gelatin and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 400-450 (L
400
QQLDISQNSVSYDEKKGDCSWTKSLLSLNMSSNILTDTIFRCLPPRIKVL
450
) of human TLR1 (Toll-like receptor 1).
SPECIFICITY:
Recognizes human and rat TLR1. Detects a band of ~87kDa. Does not cross-react with mouse TLR1.
APPLICATION:
Flow Cytometry (2-4µl per 10
6
cells)
Western Blot (1-3µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for 6 months when stored at +4°C.
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
Further Categories Containing This Product:
Polyclonal Antibodies
•
CD Antibodies
ALX-210-369
Revised 30-Oct-07
Polyclonal Antibody to Toll-like Receptor 2
SYNONYMS
anti-TLR2 PAb
anti-Toll/Interleukin-1 Receptor-like Gene 4 PAb
anti-TIL4 PAb
anti-CD282 PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
TLR Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-210-369-C100
100 µg
293.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST:
From rabbit.
CONCENTRATION:
0.5mg/ml
PURITY DETAIL:
Protein G-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide.
IMMUNOGEN:
Extracellular domain of mouse TLR2 (Toll-like receptor 2) (aa 564-580).
SPECIFICITY:
Recognizes human and mouse TLR2. Detects a band of ~86kDa by Western blot.
APPLICATION:
Western Blot (0.5-2µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 6 months when stored at +4°C.
Product Images
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