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DNA Regulation / Transcription
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ALX-201-399 Revised 27-Mar-08
Th-POK (mouse) (recombinant) (His)
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SYNONYMS T-helper-inducing POZ/Krueppel-like Factor (mouse) (recombinant) (His)
Zinc Finger Protein 67 Homolog (mouse) (recombinant) (His)
ZFP67 (mouse) (recombinant) (His)
Zinc Finger and BTB Domain-containing Protein 7B (mouse) (recombinant) (His)
ZBTB7B (mouse) (recombinant) (His)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Zinc Finger Proteins / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-399-C010   10 µg 350.00 USD Add To Cart
ALX-201-399-C050   50 µg 490.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in E. coli. Mature peptide of mouse Th-POK (zinc finger protein 67 homolog; ZFP67) (aa 1-544) is fused at the C-terminus to a His-tag.
CONCENTRATION: 1mg/ml
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM sodium chloride.
ENDOTOXIN CONTENT: <1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Images
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General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q64321: Zinc Finger and BTB Domain-containing Protein 7B (mouse)
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
 
 
ALX-201-408 Revised 27-Mar-08
Ribosomal Protein S3 (human) (recombinant) (His)
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SYNONYMS RPS3 (human) (recombinant) (His)
40S Ribosomal Protein S3
IMR-90 Ribosomal Protein S3
PRODUCT LINE Protein Synthesis, Modification & Degradation
PRODUCT CATEGORY Ribosomal Proteins / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-408-C010   10 µg 330.00 USD Add To Cart
ALX-201-408-C050   50 µg 740.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in E. coli. Mature peptide of human ribosomal protein S3 (aa 1-243) is fused at the C-terminus to a His-tag.
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in 25mM TRIS-HCl, pH 8.5, containing 1mM DTT.
ENDOTOXIN CONTENT: <1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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Product Specific Literature References
Interaction of Hsp90 with ribosomal proteins protects from ubiquitination and proteasome-dependent degradation: T.S. Kim, et al.; Mol. Biol. Cell 17, 824 (2006) Abstract; Full Text
Reduction of invasion in human fibrosarcoma cells by ribosomal protein S3 in conjunction with Nm23-H1 and ERK: S.H. Kim & J. Kim; Biochim. Biophys. Acta 1763, 823 (2006) Abstract
Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation: F. Wan, et al.; Cell 131, 927 (2007) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link P23396: Ribosomal Protein S3 (human)
MANUFACTURER Manufactured by AdipoGen, Inc.
Related Products
Further Categories Containing This Product:
Co-Chaperones & HSP-interacting Proteins / Related Products • DNA Endonucleases / Related Products • MAPK Pathway Other Products • Recombinant Proteins / Fusion Proteins • NF-kB Pathway Other Products
 
 
ALX-201-410 Revised 13-Feb-08
Ribosomal Protein S3 (human) (recombinant)
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PRODUCT LINE Protein Synthesis, Modification & Degradation
PRODUCT CATEGORY Ribosomal Proteins / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-410-C010   10 µg 330.00 USD Add To Cart
ALX-201-410-C050   50 µg 740.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in E. coli. The mature peptide of human ribosomal protein S3 (aa 1-243) is fused at the N-terminus to a tag.
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in 25mM TRIS-HCl, pH 8.5, containing 1mM DTT.
ENDOTOXIN CONTENT: <1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
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Product Specific Literature References
Interaction of Hsp90 with ribosomal proteins protects from ubiquitination and proteasome-dependent degradation: T.S. Kim, et al.; Mol. Biol. Cell 174, 824 (2006) Abstract; Full Text
Reduction of invasion in human fibrosarcoma cells by ribosomal protein S3 in conjunction with Nm23-H1 and ERK: S.H. Kim & J. Kim; Biochim. Biophys. Acta 1763, 823 (2006) Abstract
Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation: F. Wan, et al.; Cell 131, 927 (2007) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link P23396: Ribosomal Protein S3 (human)
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Co-Chaperones & HSP-interacting Proteins / Related Products • DNA Endonucleases / Related Products • Recombinant Proteins / Fusion Proteins • NF-kB Pathway Other Products • MAPK Pathway Other Products
 
 
ALX-201-426 Revised 24-Jul-08 New product
Sirtuin 1 (human) (recombinant) (His)
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SYNONYMS Sirt1 (human) (recombinant) (His)
SIR2-like Protein 1 (human) (recombinant) (His)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Sirtuins / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-426-C010   10 µg 300.00 USD Add To Cart
ALX-201-426-C050   50 µg 470.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in E. coli. The mature peptide of human sirtuin 1 (aa 2-555) is fused at the N-terminus to a His-tag.
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2μm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM sodium chloride.
ENDOTOXIN CONTENT: <1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
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General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q96EB6: SIRT1 (human)
MANUFACTURER Manufactured by AdipoGen, Inc.
Related Products
Further Categories Containing This Product:
NAD+ Metabolism / Related Products • Recombinant Proteins / Fusion Proteins • p53 Other Products
 
 
ALX-201-429 Revised 18-Sep-08 New product
NMNAT1 (human) (recombinant) (His)
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SYNONYMS NMN Adenylyltransferase 1 (human) (recombinant) (His)
Nicotinamide Mononucleotide Adenylyltransferase 1 (human) (recombinant) (His)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY NAD+ Metabolism / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-429-C010   10 µg 140.00 USD Add To Cart
ALX-201-429-C050   50 µg 280.00 USD Add To Cart
Product Specification
EC: 2.7.7.1
SOURCE/HOST: Produced in E. coli. The mature peptide of human NMNAT1 (aa 2-279) is fused at the N-terminus to a His-tag.
CONCENTRATION: 0.25mg/ml
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2μm-filtered solution in 55mM TRIS, pH 8.2, containing 150mM sodium chloride.
ENDOTOXIN CONTENT: <1EU/μg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 3 months after receipt when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles.
General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q9HAN9: NMNAT1 (human)
MANUFACTURER Manufactured by AdipoGen, Inc.
Related Products
Further Categories Containing This Product:
Enzymes • Recombinant Proteins / Fusion Proteins
 
 
ALX-201-430 Revised 12-Aug-08 New product
Sirtuin 2 (human) (recombinant) (His)
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SYNONYMS Sirt2 (human) (recombinant) (His)
SIR2-like Protein 2 (human) (recombinant) (His)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Sirtuins / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-430-C010   10 µg 300.00 USD Add To Cart
ALX-201-430-C050   50 µg 470.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in E. coli. The mature peptide of human sirtuin 2 (aa 2-389) is fused at the N-terminus to a His-tag.
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2μm-filtered solution in 50mM TRIS-Cl, pH 8.2, containing 100mM sodium chloride.
ENDOTOXIN CONTENT: <1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
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General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q8IXJ6: SIRT2 (human)
MANUFACTURER Manufactured by AdipoGen, Inc.
Related Products
Further Categories Containing This Product:
NAD+ Metabolism / Related Products • Recombinant Proteins / Fusion Proteins • p53 Other Products
 
 
ALX-202-029 Revised 08-Dec-04
Histone H1 (calf thymus)
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PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Histones / Related Products
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ALX-202-029-M001   1 mg 40.00 USD Add To Cart
Product Specification
SOURCE/HOST: Isolated from calf thymus.
PURITY: ≥98% (SDS-PAGE)
APPEARANCE: Lyophilized.
SOLUBILITY: Soluble in 100% ethanol, methanol, DMSO or aqueous solutions.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Description
Homogenous mixture of H1 subtypes.
Further Categories Containing This Product:
Natural Proteins
 
 
ALX-202-042 Revised 16-Apr-08
PARP-1 (bovine) (~90%)
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SYNONYMS Poly(ADP-ribose) Polymerase-1 (bovine) (~90%)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY PARP-1
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-202-042-C010   10 µg 180.00 USD Add To Cart
Product Specification
EC: 2.4.2.30
SOURCE/HOST: Isolated from calf thymus.
CONCENTRATION: 335μg/ml
PURITY: ~90% (SDS-PAGE, Western blot)
FORMULATION: Liquid. In 60mM kalium phosphate, pH 7.2, containing 0.5 - 2M kalium chloride, 10% glycerol, 1mM DTT, 10mM β−mercaptoethanol, 0.1mM 0.1 PMSF.
SPECIFIC ACTIVITY: 500-700U/mg protein.
One unit is defined as the amount of enzyme that synthesizes 1nmol poly(ADP-ribose) per min. at 25°C.
SHIPPING: SHIPPED ON DRY ICE
LONG TERM STORAGE: -80°C
HANDLING: Do not freeze/thaw.
Product Specific Literature References
Erasable blot of poly(ADP-ribose) polymerase: S. Desnoyers, et al.; Anal. Biochem. 218, 470 (1994) Abstract
Autoantibodies reacting with poly(ADP-ribose) and with a zinc-finger functional domain of poly(ADP-ribose) polymerase involved in the recognition of damaged DNA: S. Muller, et al.; Clin. Immunol. Immunopathol. 73, 187 (1994) Abstract
Characterization of the execution phase of apoptosis in vitro using extracts from condemned-phase cells: Y.A. Lazebnik, et al.; J. Cell Sci. Suppl. 19, 41 (1995) Abstract
Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution: Y.A. Lazebnik, et al.; PNAS 92, 9042 (1995) Abstract; Full Text
Methods for biochemical study of poly(ADP-ribose) metabolism in vitro and in vivo: G.M. Shah, et al.; Anal. Biochem. 227, 1 (1995), (Review) Abstract
Detection of poly(ADP-ribose) polymerase and its apoptosis-specific fragment by a nonisotopic activity-western blot technique: G.M. Shah, et al.; Anal. Biochem. 232, 251 (1995) Abstract
C.J. Froelich, et al.; BBRC 227, 658 (1996) Abstract
Proteolysis of poly(ADP-ribose) polymerase by caspase 3: kinetics of cleavage of mono(ADP-ribosyl)ated and DNA-bound substrates: D. D'Amours, et al.; Radiat. Res. 150, 3 (1998) Abstract
Towards new neuroprotective agents: design and synthesis of 4H-thieno[2,3-c] isoquinolin-5-one derivatives as potent PARP-1 inhibitors: R. Pellicciari, et al.; Farmaco 58, 851 (2003) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link P18493: PARP-1 (bovine)
Further Categories Containing This Product:
Enzymes • Natural Proteins
 
 
ALX-202-043 Revised 14-Feb-08
Poly(ADP-ribose) Standard
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SYNONYMS PAR Standard
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Poly(ADP-ribose) [PAR]
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ALX-202-043-C001   1 µg 230.00 USD Add To Cart
Product Specification
MW: 1’100 to 275’000 depending on the number of units of ADP-ribose.
SOURCE/HOST: Released from automodified PARP-1 by base treatment and purified by boronate affinity.
QUANTITY: 1µg representing 1.8 nanomoles of 2-300 units of ADP-ribose.
CONCENTRATION: 131.5µM
PURITY: ≥95% (HPLC of ADP-ribose RNA and DNA measurement)
FORMULATION: Liquid. In water.
APPLICATION: Immunoblotting standard for the detection of poly(ADP-ribose) (PAR) of 3-200 bases in size sythesized in vitro or in vivo.
SHIPPING: SHIPPED ON DRY ICE
LONG TERM STORAGE: -80°C
USE/STABILITY: Stable for one week when stored at +4°C. Stable for at least 2 years after receipt when stored at -80°C.
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Rapid assay of poly(ADP-ribose) glycohydrolase: L. Menard & G.G. Poirier; Biochem. Cell Biol. 65, 668 (1987) Abstract
Methods for biochemical study of poly(ADP-ribose) metabolism in vitro and in vivo.: G.M. Shah, et al.; Anal. Biochem. 227, 1 (1995) Abstract
Immunodot blot method for the detection of poly(ADP-ribose) synthesized in vitro and in vivo: E.B. Affar, et al.; Anal. Biochem. 259, 280 (1998) Abstract
Poly(ADP-ribose) turnover in quail myoblast cells: relation between the polymer level and its catabolism by glycohydrolase: E.B. Affar, et al.; Mol. Cell. Biochem. 193, 127 (1999) Abstract
Immunological determination and size characterization of poly(ADP- ribose) synthesized in vitro and in vivo: E.B. Affar, et al.; Biochim. Biophys. Acta 1428, 137 (1999) Abstract
Further Categories Containing This Product:
Natural Proteins
 
 
ALX-202-044 Revised 25-Oct-06
PARP-1 (bovine) (automodified) Standard
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SYNONYMS Poly(ADP-ribose) Polymerase-1 (bovine) (automodified) Standard
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY PARP-1
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-202-044-R100   100 µl 70.00 USD Add To Cart
Product Specification
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