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Obesity & Adipokines
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ALX-350-160 Revised 03-Sep-08 New product
Aloeresin A
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Other Natural Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-350-160-M001   1 mg 185.00 USD Add To Cart
Product Specification
FORMULA: C28H28O11
MW: 540.5
CAS NUMBER: 74545-79-2
SOURCE/HOST: Isolated from Aloe sp.
PURITY: ≥97% (HPLC)
APPEARANCE: Brown solid.
SOLUBILITY: Soluble in DMSO or 100% ethanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light.
IDENTITY: Identity determined by 1H-NMR and MS.

Product Description
Metabolite of aloesin (Prod. No. ALX-350-158).  Inhibits α-glucosidases.
Product Specific Literature References
Metabolism of aloesin and related compounds by human intestinal bacteria: a bacterial cleavage of the C-glucosyl bond and the subsequent reduction of the acetonyl side chain: Q.M. Che, et al.; Chem. Pharm. Bull. (Tokyo) 39, 704 (1991) Abstract
Geographical variation in the major compounds of Aloe ferox leaf exudate: B.E. van Wyk, et al.; Planta Med. 61, 250 (1995) Abstract
High-performance liquid chromatographic profiles of aloe constituents and determination of aloin in beverages, with reference to the EEC regulation for flavouring substances: F. Zonta, et al.; J. Chromatogr. A. 718, 99 (1995) Abstract
Determination of aloesin and aloeresin A for the detection of aloe in beverages: M. Dell’Agli, et al.; J. Agric. Food Chem. 55, 3363 (2007) Abstract
A reversed-phase high-performance liquid chromatographic method for the determination of aloesin, aloeresin A and anthraquinone in Aloe ferox: M. Zahn, et al.; Phytochem. Anal. 19, 122 (2008) Abstract
alpha-Glucosidase inhibitor from Chinese aloes: N. Jong-Anurakkun, et al.; Fitoterapia 79, 456 (2008) Abstract
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Further Categories Containing This Product:
Glycosidases / Related Products
 
 
ALX-380-262 Revised 09-Apr-08
Amidepsine A
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Other Natural Products
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ALX-380-262-M001   1 mg 230.00 USD Add To Cart
ALX-380-262-MM25   2.5 mg 470.00 USD Add To Cart
Product Specification
FORMULA: C29H29NO11
MW: 567.6
SOURCE/HOST: Isolated from fungal strain FO-2943.
PURITY: ≥95% (HPLC)
APPEARANCE: Pale white to pale yellow powder.
SOLUBILITY: Soluble in methanol or ethyl acetate; insoluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C

Product Description
Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50=10.2µM) and Raji cells (IC50=15.5µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Product Specific Literature References
Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties: H. Tomoda, et al.; J. Antibiot. 48, 937 (1995) Abstract
Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. II. Structure elucidation of amidepsines A, B and C: H. Tomoda, et al.; J. Antibiot. 48, 942 (1995) Abstract
General Information
MANUFACTURER Fungal strain courtesy of the Kitasato Institute, Tokyo.
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Further Categories Containing This Product:
Lipid Metabolism Other Products
 
 
ALX-380-263 Revised 09-Apr-08
Amidepsine D
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Other Natural Products
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ALX-380-263-M001   1 mg 230.00 USD Add To Cart
ALX-380-263-MM25   2.5 mg 470.00 USD Add To Cart
Product Specification
FORMULA: C26H24O10
MW: 496.5
SOURCE/HOST: Isolated from fungal strain FO-2943.
PURITY: ≥95% (HPLC)
APPEARANCE: White to light pink powder.
SOLUBILITY: Soluble in methanol (1mg/ml); insoluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C

Product Description
Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50=17.5µM) and Raji cells (IC50=2.8µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Product Specific Literature References
Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties: H. Tomoda, et al.; J. Antibiot. 48, 937 (1995) Abstract
Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. II. Structure elucidation of amidepsines A, B and C: H. Tomoda, et al.; J. Antibiot. 48, 942 (1995) Abstract
General Information
MANUFACTURER Fungal strain courtesy of the Kitasato Institute, Tokyo.
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Further Categories Containing This Product:
Lipid Metabolism Other Products
 
 
AG-A0722 Revised 15-Feb-08
ANGPTL6 (human) ELISA Kit
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SYNONYMS Angiopoietin-like Protein 6 (human) ELISA Kit
AGF (human) ELISA Kit
Angiopoietin-related Growth Factor (human) ELISA Kit
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
AG-A0722EK-KI01   96 wells 640.00 USD Add To Cart
AG-A0722TP-KI01 Twin Plex 2x96 wells 940.00 USD Add To Cart
AG-A0722PP-KI01 Penta Plex 5x96 wells 1'880.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY: 1.2ng/ml (range 0 to 200ng/ml)
SPECIFICITY: Does not cross-react with mouse and rat sera.
APPLICATION: For the quantitative determination of ANGPTL6 in human serum, plasma or cell culture supernatants.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
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Further Categories Containing This Product:
ELISA & EIA Kits
 
 
AG-A0822 Revised 03-Mar-08
ANGPTL3 (human) ELISA Kit
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SYNONYMS Angiopoietin-like Protein 3 (human) ELISA Kit
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
AG-A0822EK-KI01   96 wells 640.00 USD Add To Cart
AG-A0822TP-KI01 Twin Plex 2x96 wells 940.00 USD Add To Cart
AG-A0822PP-KI01 Penta Plex 5x96 wells 1'880.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY: 150pg/ml (range 0 to 20ng/ml)
SPECIFICITY: Does not cross-react with mouse and rat sera.
APPLICATION: For the quantitative determination of ANGPTL3 in human serum, plasma or cell culture supernatants.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
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Further Categories Containing This Product:
ELISA & EIA Kits
 
 
ALX-201-431 Revised 06-Aug-08 New product
ANGPTL4 (Intact Form) (human) (recombinant) (His)
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SYNONYMS Angiopoietin-like Protein 4 (Intact Form) (human) (recombinant) (His)
FIAF (Intact Form) (human) (recombinant) (His)
Fasting-induced Adipose Factor (Intact Form) (human) (recombinant) (His)
HFARP (Intact Form) (human) (recombinant) (His)
Hepatic Fibrinogen/Angiopoietin-related Protein (Intact Form) (human) (recombinant) (His)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs] / Related Products
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ALX-201-431-C010   10 µg 320.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in CHO cells. The signal peptide and the mature peptide of human ANGPTL4 (aa 1-406) are fused at the C-terminus to a His-tag.
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2μm-filtered solution in PBS.
ENDOTOXIN CONTENT: <1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q9BY76: ANGPTL4 (human)
MANUFACTURER Manufactured by AdipoGen, Inc.
General Literature References
Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation: J.C. Yoon, et al.; Mol. Cell Biol. 20, 5342 (2000) Abstract; Full Text
Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene: S. Kersten, et al.; J. Biol. Chem. 275, 28488 (2000) Abstract; Full Text
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice: A. Xu, et al.; PNAS 102, 6086 (2005) Abstract; Full Text
Genes that mediate breast cancer metastasis to lung: A.J. Minn, et al.; Nature 436, 518 (2005) Abstract; Full Text
Angiopoietin-like-4 is a potential angiogenic mediator in arthritis: L.M. Hermann, et al.; Clin. Immunol. 115, 93 (2005) Abstract
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Recombinant Proteins / Fusion Proteins
 
 
AG-DA0831 Revised 15-Feb-08
ANGPTL3 (mouse/rat) Dual ELISA Kit
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SYNONYMS Angiopoietin-like Protein 3 (mouse/rat) Dual ELISA Kit
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
AG-DA0831EK-KI01   96 wells 640.00 USD Add To Cart
AG-DA0831TP-KI01 Twin Plex 2x96 wells 940.00 USD Add To Cart
AG-DA0831PP-KI01 Penta Plex 5x96 wells 1'880.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
Rat
SENSITIVITY: 15pg/ml (range 0 to 2ng/ml)
SPECIFICITY: Does not cross-react with human sera.
APPLICATION: For the quantitative determination of ANGPTL3 in mouse or rat serum, plasma or cell culture supernatants.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Related Products
Further Categories Containing This Product:
ELISA & EIA Kits
 
 
ALX-201-387 Revised 09-Jul-08
ANGPTL1 (Fibrinogen-like Domain) (human) (recombinant)
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SYNONYMS Angiopoietin-like Protein 1 (Fibrinogen-like Domain) (human) (recombinant)
Angiopoietin-3 (Fibrinogen-like Domain) (human) (recombinant)
ANG-3 (Fibrinogen-like Domain) (human) (recombinant)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs] / Related Products
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ALX-201-387-C010   10 µg 290.00 USD Add To Cart
ALX-201-387-C050   50 µg 810.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. Fibrinogen-like domain of human ANGPTL1 (angiopoietin-like protein 1) (aa 197-491) is fused at the N-terminus to a FLAG®-tag.
CONCENTRATION: 0.3mg/ml
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE