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AG-AE0631
Revised 11-Jan-08
ACE2 (human) ELISA Kit
SYNONYMS
Angiotensin-converting Enzyme 2 (human) ELISA Kit
SARS Receptor (human) ELISA Kit
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
Angiotensin Converting Enzyme [ACE] & ACE2 / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
AG-AE0631EK-KI01
96 wells
590.00 USD
AG-AE0631TP-KI01
Twin Plex
2x96 wells
890.00 USD
AG-AE0631PP-KI01
Penta Plex
5x96 wells
1'870.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY:
293pg/ml (range 0 to 50ng/ml)
APPLICATION:
For the quantitative determination of ACE2 in human urine samples or cell culture supernatants.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
SARS Coronavirus / Related Products
•
ELISA & EIA Kits
ALX-201-221
Revised 02-Oct-06
Pin1 (human) (recombinant)
SYNONYMS
Peptidyl-prolyl
cis-trans
Isomerase Pin1 (human) (recombinant)
PPIase Pin1 (human) (recombinant)
Peptidyl-prolyl
cis-trans
Isomerase NIMA-interacting 1 (human) (recombinant)
PPIase NIMA-interacting 1 (human) (recombinant)
Rotamase Pin1 (human) (recombinant)
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
Alzheimer Research Other Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
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ALX-201-221-C100
100 µg
325.00 USD
Product Specification
MW:
~18.2kDa
SOURCE/HOST:
Recombinant human peptidyl-prolyl
cis
-
trans
isomerase (PPIase) Pin1 produced in
E. coli
.
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE)
FORMULATION:
Liquid. In 20mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 5mM DTT and 20% glycerol.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Stress & Heat Shock Proteins Other Products
•
Recombinant Proteins / Fusion Proteins
•
Antiviral Signalling / Related Products
•
p53 Other Products
ALX-201-247
Revised 18-Mar-08
NS3-NS4A (HCV) (recombinant) (His)
SYNONYMS
Nonstructural Protein 3-NS4A (HCV) (recombinant) (His)
Hepacivirin-NS4A (HCV) (recombinant) (His)
PRODUCT LINE
Viral Signalling
PRODUCT CATEGORY
Hepatitis Viruses / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-201-247-C100
100 µg
210.00 USD
Product Specification
MW:
~68.7kDa (NS3 subunit); ~6.2kDa (NS4A subunit)
EC:
3.4.21.98
SOURCE/HOST:
Produced in
E. coli
. Recombinant hepatitis C virus (HCV) NS3-NS4A serine protease complex is fused to a His-tag.
CONCENTRATION:
379ng/μl (5µM)
PURITY:
≥85% (SDS-PAGE)
FORMULATION:
Liquid. In 25mM HEPES, pH 7.6, containing 1mM EDTA, 3mM DTT, 0.5M sodium chloride, 0.2% Triton X-100 and 20% glycerol.
BIOLOGICAL ACTIVITY:
IC
50
(lot-specific)
APPLICATION:
Suitable for screenings.
SHIPPING:
SHIPPED ON DRY ICE
LONG TERM STORAGE:
-80°C
HANDLING:
Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
ALX-201-330
Revised 24-Jul-06
ACE2 (human):Fc (human) (recombinant)
SYNONYMS
Angiotensin-converting Enzyme 2 (human):Fc (human) (recombinant)
SARS Receptor (human):Fc (human) (recombinant)
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
Angiotensin Converting Enzyme [ACE] & ACE2 / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-201-330-C050
50 µg
370.00 USD
Product Specification
SOURCE/HOST:
Produced in HEK 293 cells. The signal peptide sequence and the extracellular domain of human ACE2 (angiotensin-converting enzyme 2) (aa 1-740) are fused at the C-terminus to the Fc portion of human IgG1.
CONCENTRATION:
1mg/ml
PURITY:
≥90% (SDS-PAGE)
FORMULATION:
Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT:
<0.1EU/µg protein (LAL test).
BIOLOGICAL ACTIVITY:
Converts angiotensin I to angiotensin-(1-9).
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
BACKGROUND/TECHNICAL INFORMATION
Swiss-Prot link Q9NRA7:
Angiotensin converting enzyme-like protein (human)
MANUFACTURER
Manufactured by Adipogen, Inc.
Further Categories Containing This Product:
SARS Coronavirus / Related Products
•
Recombinant Proteins / Fusion Proteins
ALX-201-356
Revised 18-Mar-08
ACE2, Soluble (human) (recombinant)
SYNONYMS
Angiotensin-converting Enzyme 2, Soluble (human) (recombinant)
SARS Receptor, Soluble (human) (recombinant)
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
Angiotensin Converting Enzyme [ACE] & ACE2 / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-201-356-C010
10 µg
295.00 USD
ALX-201-356-C050
50 µg
795.00 USD
Product Specification
EC:
3.4.17.-
SOURCE/HOST:
Produced in HEK 293 cells. The signal peptide sequence and the extracellular domain of human ACE2 (angiotensin-converting enzyme 2) (aa 1-740) are fused at the C-terminus to a FLAG
®
-tag.
CONCENTRATION:
1mg/ml
PURITY:
≥90% (SDS-PAGE)
FORMULATION:
Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT:
<0.1EU/µg protein (LAL-test).
BIOLOGICAL ACTIVITY:
Converts angiotensin I to angiotensin-(1-9).
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
General Information
BACKGROUND/TECHNICAL INFORMATION
Swiss-Prot link Q9NRA7:
Angiotensin converting enzyme-like protein (human)
FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER
Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
SARS Coronavirus / Related Products
•
Recombinant Proteins / Fusion Proteins
ALX-210-028
Revised 01-Mar-07
Polyclonal Antibody to TRAF6 (Bur 30)
SYNONYMS
anti-Tumor Necrosis Factor (TNF) Receptor-associated Factor 6 PAb (Bur 30)
anti-RING Finger Protein 85 PAb (Bur 30)
anti-Interleukin-1 Signal Transducer PAb (Bur 30)
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
TRAFs / Related Products
Ordering Information
Product Numbers:
Format:
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ALX-210-028-R050
50 µl
190.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST:
From rabbit.
FORMULATION:
Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 451-469 (D
451
AKPELLAFQRPTIPRNPK
469
) of human TRAF6 (tumor necrosis factor (TNF) receptor-associated factor 6). This sequence is completely conserved in mouse TRAF6.
SPECIFICITY:
Recognizes human and mouse TRAF6. Detects a band of ~65kDa by Western blot. Does not cross-react with other members of the TRAF family.
APPLICATION:
Immunohistochemistry (paraffin sections (1:1'000))
Western Blot (1:500-1:2'000)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-80°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored at -80°C.
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies
:
J.M. Zapata, et al.; J. Immunol.
165
, 5084 (2000)
Abstract
;
Full Text
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Autoimmunity & Self Tolerance Other Products
•
Antiviral Signalling / Related Products
•
Polyclonal Antibodies
ALX-210-352
Revised 30-Oct-06
Polyclonal Antibody to MDA5 (mouse) (AL180)
SYNONYMS
anti-Melanoma Differentiation-associated Gene 5 (mouse) PAb (AL180)
anti-Helicard (mouse) PAb (AL180)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
RNA Helicases / Related Products
Ordering Information
Product Numbers:
Format:
Size:
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ALX-210-352-C100
100 µg
270.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST:
From rabbit.
FORMULATION:
Liquid. Contains 0.02% sodium azide.
IMMUNOGEN:
Recombinant mouse MDA5 (melanoma differentiation-associated gene 5) (aa 2-208).
SPECIFICITY:
Recognizes mouse MDA5.
APPLICATION:
Western Blot
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored as recommended.
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
Overexpression of Helicard, a CARD-Containing Helicase Cleaved during Apoptosis, Accelerates DNA Degradation:
M. Kovacsovics, et al.; Curr. Biol.
12
, 838 (2002)
Abstract
General Information
MDA5 is a highly conserved helicase whose ATPase activity can be stimulated by RNA and less potently by DNA. It contains two N-terminal CARD domains and a C-terminal helicase domain. The helicase domain, once freed from the CARD domains, then translocates from the cytoplasm to the nucleus where it acts on chromatin architecture. This could allow a more easy access of CAD, thereby accelerating the degradation of genomic DNA.
MANUFACTURER
Manufactured by Apotech Corporation.
General Literature References
Mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties
:
D.C. Kang, et al.; PNAS
99
, 637 (2002)
Abstract
Related Products
ALX-210-935
Polyclonal Antibody to MDA5 (human) (AT113)
ALX-804-863
Monoclonal Antibody to MDA5 (human) (Hely-1)
APO-54N-035
MDA5 (human) Detection Set (IntraCellular) [For ELISA Application]
APO-54N-039
MDA5 (human) ELISA Kit (IntraCellular)
Further Categories Containing This Product:
NF-kB Pathway Other Products
•
Antiviral Signalling / Related Products
•
Polyclonal Antibodies
•
Caspase Recruitment Domain [CARD] Proteins / Related Products
•
Interferons & Interferon Receptors Other Products
ALX-210-367
Revised 25-Sep-08
Polyclonal Antibody to Toll-like Receptor 3 (mouse)
SYNONYMS
anti-TLR3 (mouse) PAb
anti-CD283 (mouse) PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
TLR Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-367-R200
200 µl
293.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST:
From rabbit.
CONCENTRATION:
0.5mg/ml
PURITY DETAIL:
Protein G-affinity purified.
FORMULATION:
Liquid. In PBS containing 0.2% gelatin and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptides corresponding to aa 135-150, 828-844 and 876-891 of mouse TLR3 (Toll-like receptor 3).
SPECIFICITY:
Recognizes mouse TLR3. Does not cross-react with human TLR3.
APPLICATION:
Flow Cytometry (cell surface & intracellular (1μg/10
6
cells) (see [2]))
Immunohistochemistry (paraffin sections (1:50), frozen sections (see [1]))
Western Blot (1-3µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for 6 months when stored at +4°C.
HANDLING:
Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
[1]
Viral double-stranded RNA aggravates lupus nephritis through Toll-like receptor 3 on glomerular mesangial cells and antigen-presenting cells:
P.S. Patole, et al.; J. Am. Soc. Nephrol.
16
, 1326 (2005)
Abstract
[2]
Toll-like receptor-7 modulates immune complex glomerulonephritis:
R.D. Pawar, et al.; J. Am. Soc. Nephrol.
17
, 141 (2006)
Abstract
[3]
Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice:
P.S. Patole, et al.; Nephrol. Dial. Transplant.
21
, 3062 (2006)
Abstract
Further Categories Containing This Product:
Polyclonal Antibodies
•
Antiviral Signalling / Related Products
•
CD Antibodies
ALX-210-444
Revised 25-Jul-07
Polyclonal Antibody to ACE2 (human)
SYNONYMS
anti-Angiotensin-converting Enzyme 2 (human) PAb
anti-SARS Receptor (human) PAb
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
Angiotensin Converting Enzyme [ACE] & ACE2 / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-444-C100
100 µg
340.00 USD
ALX-210-444B-C050
Biotin
50 µg
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml.
PURITY DETAIL:
Purified IgG.
FORMULATION:
Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN:
Recombinant human ACE2 (angiotensin-converting enzyme 2).
SPECIFICITY:
Recognizes human ACE2.
APPLICATION:
ELISA
(direct and indirect: 1:2’000-1:10’000)
Western Blot
1:2’000-1:10’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
SARS Coronavirus / Related Products
•
Polyclonal Antibodies
ALX-210-908
Revised 14-Jan-08
Polyclonal Antibody to TRIF (human) (AL227)
SYNONYMS
anti-TICAM-1 (human) PAb (AL227)
anti-TIR-containing Adaptor Molecule-1 (human) PAb (AL227)
anti-Toll-interleukin-1 Receptor [TIR] Domain-containing Adaptor Inducing Interferon-β [IFN-β] (human) PAb (AL227)
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
Toll-IL-1 Receptor Adaptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-908-C050
50 µg
190.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml
PURITY DETAIL:
Affinity purified.
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 4-31 (T
4
GPSLPSAFDIL
GAAGQDKLLYLKHKLK
31
) of N-terminal human TRIF [TICAM-1].
SPECIFICITY:
Recognizes human TRIF.
APPLICATION:
Immunoprecipitation
Western Blot
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored at -20°C.
HANDLING:
Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling:
M. Carty, et al.; Nat. Immunol.
7
, 1074 (2006)
Abstract
Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells:
E. Aksoy, et al.; Blood
109
, 2887 (2007)
Abstract
;
Full Text
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Polyclonal Antibodies
•
Antiviral Signalling / Related Products
ALX-210-929
Revised 16-Apr-08
Polyclonal Antibody to Cardif (human) (AT107)
